swa cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	swa
Entrez Gene ID	31580
Full Name	swallow
Synonyms	CG3429,Dmel\CG3429,Swa,anon-WO0140519.70,fs(1)1497,fs(1)1502,fs(1)M11-999,fs(1)M13C82,fs(1)M44,fs(1)m44,sww
General protein information	Preferred Names swallow Names CG3429 gene product from transcript CG3429-RA CG3429-PA swa-PA
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: X Map Location: 5F4-5F4\|1-15.9 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_078505.4	NP_511060.2	swallow

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Swa is crucial for the organization of actin networks that lead to the formation of a specialized microtubule population, while Ovhts-RC acts to modulate spatially restricted actin filament growth at the oocyte cortex.
Title: Distinct roles for hu li tai shao and swallow in cytoskeletal organization during Drosophila oogenesis.

Results exclude a role for Swallow in linking bicoid mRNA to the dynein motor.
Title: Distinguishing direct from indirect roles for bicoid mRNA localization factors.

binding of LC8 to Swallow serves another function, possibly that of a dimerization engine, which is independent of its role in dynein
Title: Structure and dynamics of LC8 complexes with KXTQT-motif peptides: swallow and dynein intermediate chain compete for a common site.

The weak coiled-coil domain of Drosophila swallow binds tightly to LC8 and becomes significantly more stable in vitro, less susceptible to proteolysis, and more capable of binding other macromolecules in the dynein complex.
Title: Dynein light chain LC8 promotes assembly of the coiled-coil domain of swallow protein.

Molecular characterization of alleles of swallow that may affect swallow function.
Title: Identification of hypomorphic and null alleles of swallow via molecular and phenotypic analyses.

The following swa gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the swa cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa03136	NM_078505.4 Latest version!	Drosophila melanogaster swallow (swa), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

swa ( NM_078505.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_511060.2 Drosophila melanogaster swallow (swa), mRNA.

Price & Availability↑

CloneID	OFa03136
Clone ID Related Accession (Same CDS sequence)	NM_078505.4
Accession Version	NM_078505.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1647bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	swallow
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Jul 15, 2014 this sequence version replaced NM_078505.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGAGTCTAC AGGACGAGAG TTTTCCGACG GACGAGCTGT TTGACCAGCT GAACAATTTG 
AGTAGCAGTG GCGCCAGGAA TACCTGGTTC GCGGAGCACC ATAAGCCCGC AGTCTTCGAG 
CGGGATACAG CGCCATTTTT GGAGATCTGC TACGCGGATC CAGACTTTGA TGCGGATGGG 
GATGTGGCCA ACAAGAGCGC CAAGACATGC GTAAGCGATC CCGTGGGTCG TGATCAGGAG 
GATGAGGACG ACTATGATGA GGATGTCGAT GGCGATGATC ATAAACTGGG TTGCGAGAAG 
GCTCCATTGG GCAGCGGGCG CTCCAGCAAG GCGGTCTCTT ACCAGGACAT CCATTCGGCC 
TACACGAAGC GCCGCTTCCA GCACGTGACC AGCAAGGTGG GCCAGTACAT AGCGGAGATC 
CAGGCGCAGG ACCAAAAGAG ACGCAATGTG AAGTTCGCCG GATTCCAGCG AGTGAACTCT 
ATGCCGGAGA GTCTAACGCC CACATTGCAG CAGGTGTATG TCCATGATGG TGACTTCAAG 
GTGGACAAAA ACTGCCAGAC TCACTCCAAC TCCGATTCGA ATTACAATTC CAATTCAAAC 
AACTCTAGCA GCAGCTTTGA TCGATTGCTG GCCGAGAACG AGAGCCTGCA GCAAAAGATC 
AACTCATTGA GAGTAGAAGC GAAGCGTCTG CAGGGCTTCA ACGAGTATGT CCAGGAACGA 
CTGGACAGAA AGACAGATGA TTTTGTGAAG ATGAAGTGCA ATTTCGAGAC CCTGCGCACC 
GAGCTAAGCG AATGCCAGCA GAAGCTTAGG CGCCAGCAGG ACAACTCACA GCACCACTTC 
ATGTACCACA TTCGATCGGC GACCAGTGCC AAGGCCACTC AAACGGATTT CCTGGTGGAC 
ACCATACCCG CCTCCGGAAA CGTCCTGGTC ACACCCCATC CCCTGGGCGA CCTGACCTAC 
AACAGCAGCA AAGGATCCAT CGAGTTGGCA CTGCTCAGTG TGGCGCCTTC TGCCCGAGTG 
GCCCAGAATC CCGTCCAGGT CCAACGCGCG ATTCATCCAC AATCTTTGGA CTTTAGCAGC 
GTTAGCACCG AAGCTGATGG CAGCGGTAGT GGCGAACATC GTGTGGAAAC CTCATCCAGG 
GCCTTGGTCA GAAGAACCCC GGCGCCCAAC AACTCGGAAA CCAGCCAGCC GAGCAGCAAC 
GACTCGGCCA TCGAGGTGGA GGCGCACGAG GAGGAGCGAC CCAGCTCCAG GCGGCAGTGG 
GAACAACAGG GGGAGCTCAT CTCGCCCAGG CAATGGGGCC AGCATGAGGG CATGTACTAC 
TTTGACAAGC GCAACAACCG AGTCATCGAG GTGATGGGCT TCAATATCAG TCAGGGGCGC 
AATCAGAGCC ATGACACCAT TCATAATCAG AGCATCAACG ATAGTCAGAC GCGTCTGCTG 
GTCCACTCGA TGTCGATGTC GCATTTGGAG GCGCATGACC ACTTTAGGAG TAAAAGGACG 
ACACTGGGCA GTCGGATGCT ACGATTCCTG GGGCCCTGCG TTCGCTGCCG TAATGGTGAT 
CCATTGAACC GCAGCAATGT CACATACAAG GATGGTTTGC CTGCGATGCC CGAGGAGGAG 
TTCGTTGACC AAAGGAACCA GCGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_511060.2
CDS	113..1759
Translation	MSLQDESFPTDELFDQLNNLSSSGARNTWFAEHHKPAVFERDTAPFLEICYADPDFDADGDVANKSAKTCVSDPVGRDQEDEDDYDEDVDGDDHKLGCEKAPLGSGRSSKAVSYQDIHSAYTKRRFQHVTSKVGQYIAEIQAQDQKRRNVKFAGFQRVNSMPESLTPTLQQVYVHDGDFKVDKNCQTHSNSDSNYNSNSNNSSSSFDRLLAENESLQQKINSLRVEAKRLQGFNEYVQERLDRKTDDFVKMKCNFETLRTELSECQQKLRRQQDNSQHHFMYHIRSATSAKATQTDFLVDTIPASGNVLVTPHPLGDLTYNSSKGSIELALLSVAPSARVAQNPVQVQRAIHPQSLDFSSVSTEADGSGSGEHRVETSSRALVRRTPAPNNSETSQPSSNDSAIEVEAHEEERPSSRRQWEQQGELISPRQWGQHEGMYYFDKRNNRVIEVMGFNISQGRNQSHDTIHNQSINDSQTRLLVHSMSMSHLEAHDHFRSKRTTLGSRMLRFLGPCVRCRNGDPLNRSNVTYKDGLPAMPEEEFVDQRNQR

Target ORF information:

RefSeq Version	NM_078505.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster swallow (swa), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_078505.4

ORF Insert Sequence:

ATGAGTCTAC AGGACGAGAG TTTTCCGACG GACGAGCTGT TTGACCAGCT GAACAATTTG 
AGTAGCAGTG GCGCCAGGAA TACCTGGTTC GCGGAGCACC ATAAGCCCGC AGTCTTCGAG 
CGGGATACAG CGCCATTTTT GGAGATCTGC TACGCGGATC CAGACTTTGA TGCGGATGGG 
GATGTGGCCA ACAAGAGCGC CAAGACATGC GTAAGCGATC CCGTGGGTCG TGATCAGGAG 
GATGAGGACG ACTATGATGA GGATGTCGAT GGCGATGATC ATAAACTGGG TTGCGAGAAG 
GCTCCATTGG GCAGCGGGCG CTCCAGCAAG GCGGTCTCTT ACCAGGACAT CCATTCGGCC 
TACACGAAGC GCCGCTTCCA GCACGTGACC AGCAAGGTGG GCCAGTACAT AGCGGAGATC 
CAGGCGCAGG ACCAAAAGAG ACGCAATGTG AAGTTCGCCG GATTCCAGCG AGTGAACTCT 
ATGCCGGAGA GTCTAACGCC CACATTGCAG CAGGTGTATG TCCATGATGG TGACTTCAAG 
GTGGACAAAA ACTGCCAGAC TCACTCCAAC TCCGATTCGA ATTACAATTC CAATTCAAAC 
AACTCTAGCA GCAGCTTTGA TCGATTGCTG GCCGAGAACG AGAGCCTGCA GCAAAAGATC 
AACTCATTGA GAGTAGAAGC GAAGCGTCTG CAGGGCTTCA ACGAGTATGT CCAGGAACGA 
CTGGACAGAA AGACAGATGA TTTTGTGAAG ATGAAGTGCA ATTTCGAGAC CCTGCGCACC 
GAGCTAAGCG AATGCCAGCA GAAGCTTAGG CGCCAGCAGG ACAACTCACA GCACCACTTC 
ATGTACCACA TTCGATCGGC GACCAGTGCC AAGGCCACTC AAACGGATTT CCTGGTGGAC 
ACCATACCCG CCTCCGGAAA CGTCCTGGTC ACACCCCATC CCCTGGGCGA CCTGACCTAC 
AACAGCAGCA AAGGATCCAT CGAGTTGGCA CTGCTCAGTG TGGCGCCTTC TGCCCGAGTG 
GCCCAGAATC CCGTCCAGGT CCAACGCGCG ATTCATCCAC AATCTTTGGA CTTTAGCAGC 
GTTAGCACCG AAGCTGATGG CAGCGGTAGT GGCGAACATC GTGTGGAAAC CTCATCCAGG 
GCCTTGGTCA GAAGAACCCC GGCGCCCAAC AACTCGGAAA CCAGCCAGCC GAGCAGCAAC 
GACTCGGCCA TCGAGGTGGA GGCGCACGAG GAGGAGCGAC CCAGCTCCAG GCGGCAGTGG 
GAACAACAGG GGGAGCTCAT CTCGCCCAGG CAATGGGGCC AGCATGAGGG CATGTACTAC 
TTTGACAAGC GCAACAACCG AGTCATCGAG GTGATGGGCT TCAATATCAG TCAGGGGCGC 
AATCAGAGCC ATGACACCAT TCATAATCAG AGCATCAACG ATAGTCAGAC GCGTCTGCTG 
GTCCACTCGA TGTCGATGTC GCATTTGGAG GCGCATGACC ACTTTAGGAG TAAAAGGACG 
ACACTGGGCA GTCGGATGCT ACGATTCCTG GGGCCCTGCG TTCGCTGCCG TAATGGTGAT 
CCATTGAACC GCAGCAATGT CACATACAAG GATGGTTTGC CTGCGATGCC CGAGGAGGAG 
TTCGTTGACC AAAGGAACCA GCGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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swa cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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