oaz2b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	oaz2b
Entrez Gene ID	790945
Full Name	ornithine decarboxylase antizyme 2b
Synonyms	AZR,oaz2l
General protein information	Preferred Names ornithine decarboxylase antizyme 2b Names ornithine decarboxylase antizyme 2b antizyme retina
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)
Summary	The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cells. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. Several antizyme paralogs have been described in zebrafish. This gene encodes a novel antizyme, which is preferentially expressed in the retinal ganglion cell layer of the eye. [provided by RefSeq, Jan 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001080090.1	NP_001073559.1	ornithine decarboxylase antizyme 2b

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Structure-toxicity relationship of cefoperazone and its impurities to developing zebrafish by transcriptome and Raman analysis.
Han Y, Qian J, Zhang J, Hu C, Wang C
Toxicology and applied pharmacology32739-51(2017 07)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Discovery and characterization of novel vascular and hematopoietic genes downstream of etsrp in zebrafish.
Gomez GA, Veldman MB, Zhao Y, Burgess S, Lin S
PloS one4(3)e4994(2009)

Ribosomal frameshifting in decoding antizyme mRNAs from yeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation.
Ivanov IP, Atkins JF
Nucleic acids research35(6)1842-58(2007)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following oaz2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the oaz2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa98442	NM_001080090.1 Latest version!	Danio rerio ornithine decarboxylase antizyme 2b (oaz2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

oaz2b ( NM_001080090.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001073559.1 Danio rerio ornithine decarboxylase antizyme 2b (oaz2b), mRNA.

Price & Availability↑

CloneID	ODa98442
Clone ID Related Accession (Same CDS sequence)	NM_001080090.1
Accession Version	NM_001080090.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	ornithine decarboxylase antizyme 2b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC076348.1, BC122186.1, BC142811.1, EH473981.1 and BI981995.1. On Dec 19, 2008 this sequence version replaced XM_001339413.2. ##Evidence-Data-START## Transcript exon combination :: BC107610.1, CN017320.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## ribosomal slippage :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGATCAACA CACAAGCAAG AGCTGTTCTC CTGGATTCAG CATGTGTGCT CCGCTGGGTC 
AGGCTGCAGG CTCCGGGGCC TCAGTGGTGC TCCGATGCCC CTCATACAAA GATGAGCACA 
GCCGGACAAG ATGTGAACAG GGATCTGAAT CAAGATGTGC TCCTTTACAA GGATGGGAAG 
TTGACAGTGA AACAGGTATC CTCGCTGGAC AGTGACTCAT CAGTTCTGCT CTTTCAGTAC 
GAGCTCAGTG AGCAGTTGTC ATGGAGCATG CAGACTGTGC TTTCTGGCCA CAGCCTCTTT 
GTTGGTTTAC CAAATGGAGA ACTTCTAAAA GGCACCAAAG AAGGGCTCAC TGCTGTTTTG 
GAGTTTGCAG AGGAGAAACT GAAGATCAGT CATGTATTTG TCTGGTTCAT GAAGAACAGG 
CCAGATAAAT TGCTCCTCAC CAGAACATTC TTCTACCTTG GCTTTGAACT TGTAAAACCA 
GATCATCTTA TAGCATCGAT AGCAGGAGAT TTGCGTCTTA TGGTCTACAC AATACAACAA 
ACTCACTCAT CTGAGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073559.1
CDS	join(90..182,184..651)
Translation	MINTQARAVLLDSACVLRWVRLQAPGPQWCSDAPHTKMSTAGQDVNRDLNQDVLLYKDGKLTVKQVSSLDSDSSVLLFQYELSEQLSWSMQTVLSGHSLFVGLPNGELLKGTKEGLTAVLEFAEEKLKISHVFVWFMKNRPDKLLLTRTFFYLGFELVKPDHLIASIAGDLRLMVYTIQQTHSSEE

Target ORF information:

RefSeq Version	NM_001080090.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio ornithine decarboxylase antizyme 2b (oaz2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080090.1

ORF Insert Sequence:

ATGATCAACA CACAAGCAAG AGCTGTTCTC CTGGATTCAG CATGTGTGCT CCGCTGGGTC 
AGGCTGCAGG CTCCGGGGCC TCAGTGGTGC TCCGATGCCC CTCATACAAA GATGAGCACA 
GCCGGACAAG ATGTGAACAG GGATCTGAAT CAAGATGTGC TCCTTTACAA GGATGGGAAG 
TTGACAGTGA AACAGGTATC CTCGCTGGAC AGTGACTCAT CAGTTCTGCT CTTTCAGTAC 
GAGCTCAGTG AGCAGTTGTC ATGGAGCATG CAGACTGTGC TTTCTGGCCA CAGCCTCTTT 
GTTGGTTTAC CAAATGGAGA ACTTCTAAAA GGCACCAAAG AAGGGCTCAC TGCTGTTTTG 
GAGTTTGCAG AGGAGAAACT GAAGATCAGT CATGTATTTG TCTGGTTCAT GAAGAACAGG 
CCAGATAAAT TGCTCCTCAC CAGAACATTC TTCTACCTTG GCTTTGAACT TGTAAAACCA 
GATCATCTTA TAGCATCGAT AGCAGGAGAT TTGCGTCTTA TGGTCTACAC AATACAACAA 
ACTCACTCAT CTGAGGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structure-toxicity relationship of cefoperazone and its impurities to developing zebrafish by transcriptome and Raman analysis.
Toxicology and applied pharmacology32739-51(2017 07)
Han Y,Qian J,Zhang J,Hu C,Wang C

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Discovery and characterization of novel vascular and hematopoietic genes downstream of etsrp in zebrafish.
PloS one4(3)e4994(2009)
Gomez GA,Veldman MB,Zhao Y,Burgess S,Lin S

Ribosomal frameshifting in decoding antizyme mRNAs from yeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation.
Nucleic acids research35(6)1842-58(2007)
Ivanov IP,Atkins JF

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oaz2b cDNA ORF clone, Danio rerio(zebrafish)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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