atox1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	atox1
Entrez Gene ID	558347
Full Name	antioxidant 1 copper chaperone
General protein information	Preferred Names antioxidant 1 copper chaperone Names copper transport protein ATOX1 ATX1 antioxidant protein 1 homolog copper chaperone
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001256633.3	NP_001243562.1	copper transport protein ATOX1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ATOX1	NP_001003119.1
Bos taurus (cattle)	ATOX1	NP_001124230.1
	LOC712464	XP_001101466.2
Danio rerio (zebrafish)	atox1	NP_001243562.1
Homo sapiens (human)	ATOX1	NP_004036.1
Mus musculus (house mouse)	Atox1	NP_033850.1
Xenopus tropicalis (tropical clawed frog)	atox1	NP_001039238.1
Pan troglodytes (chimpanzee)	ATOX1	XP_001169183.1
Rattus norvegicus (Norway rat)	Atox1	NP_445811.1
Gallus gallus (chicken)	ATOX1	NP_001264641.1

Gene Ontology
Bibliography

Related articles in PubMed

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Understanding copper sensitivity in zebrafish (Danio rerio) through the intracellular localization of copper transporters in a hepatocyte cell-line ZFL and the tissue expression profiles of copper transporters.
Leung KP, Chen D, Chan KM
Metallomics : integrated biometal science6(5)1057-67(2014 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following atox1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the atox1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa03333	NM_001256633.3 Latest version!	Danio rerio antioxidant 1 copper chaperone (atox1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

atox1 ( NM_001256633.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001243562.1 Danio rerio antioxidant 1 copper chaperone (atox1), mRNA.

Price & Availability↑

CloneID	ODa03333
Clone ID Related Accession (Same CDS sequence)	NM_001256633.3
Accession Version	NM_001256633.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 204bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Danio rerio(zebrafish)
Product	copper transport protein ATOX1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR954266.16, EH607067.1, EH450861.1 and EH592078.1. On Oct 24, 2014 this sequence version replaced NM_001256633.2. ##Evidence-Data-START## Transcript exon combination :: GDQH01005650.1, EH607067.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476822, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACGACTC ACGAGTTTTT TGTTGACATG ACATGTGAAG GATGCTCTGG TGCAGTCACT 
CGAGTACTTA ATAAACTGGA TGTCAAGTTT GATATCGATC TTCCCAACAA GAAGGTCTTC 
ATTGAGTCAG ACAAAAACAC TGATGTCCTT CTGGAAACAC TAAAAAAGAC TGGAAAAACT 
GTTACCTACA TTGGTACAAA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243562.1
CDS	92..295
Translation	MTTHEFFVDMTCEGCSGAVTRVLNKLDVKFDIDLPNKKVFIESDKNTDVLLETLKKTGKTVTYIGTK

Target ORF information:

RefSeq Version	NM_001256633.3
Organism	Danio rerio(zebrafish)
Definition	Danio rerio antioxidant 1 copper chaperone (atox1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256633.3

ORF Insert Sequence:

ATGACGACTC ACGAGTTTTT TGTTGACATG ACATGTGAAG GATGCTCTGG TGCAGTCACT 
CGAGTACTTA ATAAACTGGA TGTCAAGTTT GATATCGATC TTCCCAACAA GAAGGTCTTC 
ATTGAGTCAG ACAAAAACAC TGATGTCCTT CTGGAAACAC TAAAAAAGAC TGGAAAAACT 
GTTACCTACA TTGGTACAAA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Understanding copper sensitivity in zebrafish (Danio rerio) through the intracellular localization of copper transporters in a hepatocyte cell-line ZFL and the tissue expression profiles of copper transporters.
Metallomics : integrated biometal science6(5)1057-67(2014 May)
Leung KP,Chen D,Chan KM