lta cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	lta
Entrez Gene ID	554305
Full Name	lymphotoxin alpha (TNF superfamily, member 1)
Synonyms	TNF-N
General protein information	Preferred Names lymphotoxin alpha (TNF superfamily, member 1) Names lymphotoxin alpha LT-alpha
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_009291801.2	XP_009290076.1	lymphotoxin alpha isoform X1
XM_009291801.3	XP_009290076.1	lymphotoxin alpha isoform X1
NM_001024821.1	NP_001019992.1	lymphotoxin alpha

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Hepatotoxicity of benzotriazole and its effect on the cadmium induced toxicity in zebrafish Danio rerio.
Duan Z, Xing Y, Feng Z, Zhang H, Li C, Gong Z, Wang L, Sun H
Environmental pollution (Barking, Essex : 1987)224706-713(2017 May)

Transcriptome profiling analysis of naked carp (Gymnocypris przewalskii) provides insights into the immune-related genes in highland fish.
Tong C, Zhang C, Zhang R, Zhao K
Fish & shellfish immunology46(2)366-77(2015 Oct)

Evolutionary evidence of tumor necrosis factor super family members in the Japanese pufferfish (Takifugu rubripes): Comprehensive genomic identification and expression analysis.
Biswas G, Kinoshita S, Kono T, Hikima J, Sakai M
Marine genomics2225-36(2015 Aug)

The proprotein convertase subtilisin/kexin furinA regulates zebrafish host response against Mycobacterium marinum.
Ojanen MJ, Turpeinen H, Cordova ZM, Hammar?n MM, Harjula SK, Parikka M, R?met M, Pesu M
Infection and immunity83(4)1431-42(2015 Apr)

Presence of two tumor necrosis factor (tnf)-? homologs on different chromosomes of zebrafish (Danio rerio) and medaka (Oryzias latipes).
Kinoshita S, Biswas G, Kono T, Hikima J, Sakai M
Marine genomics131-9(2014 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following lta gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lta cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa36863	NM_001024821.1 Latest version!	Danio rerio lymphotoxin alpha (TNF superfamily, member 1) (lta), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
ODa36863	XM_009291801.3 Latest version!	Danio rerio lymphotoxin alpha (TNF superfamily, member 1) (lta), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
View Old Accession Versions >>
ODa36863	XM_009291801.2	Danio rerio lymphotoxin alpha (TNF superfamily, member 1) (lta), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

lta ( NM_001024821.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001019992.1 Danio rerio lymphotoxin alpha (TNF superfamily, member 1) (lta), mRNA.

Price & Availability↑

CloneID	ODa36863
Clone ID Related Accession (Same CDS sequence)	XM_009291801.2 , XM_009291801.3 , NM_001024821.1
Accession Version	NM_001024821.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-01-12
Organism	Danio rerio(zebrafish)
Product	lymphotoxin alpha
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB183468.1. On Jul 6, 2005 this sequence version replaced XM_698624.1. ##Evidence-Data-START## Transcript exon combination :: AB183468.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGACCGGCC AGAGTAACCC CAGGTTCCGC CTCCTGATTG GCTGGTGCTG CCTGATGAGC 
TCAGCTCTTT TGATGATGAC CGTATATCTC GCGACAAGTT CGAACAAACA GTCTGAAACA 
AACACGACAA CATCTGAACA CCACAGTTCA GCAGGACCTC AAGAAAAGAG AGTCCAATTT 
TCAGAACTTC AAGCTCTGAA TGTTATCGAC TACATCCGTC TGCTCAAAGA TAAGAAAAAA 
ATCTGGATAT GCACTCAACC ATGCAAAAGC AAAAGGCTTA AACTGAACAA CAGCAGCGTT 
GAAATTGCAA GCACTGGCCT GTACCACATT CATGCTCAGG TCGGCTTTAA GAGACATGAG 
AGCACGCAGG AAACAAAGAA GACTCCACAA AAAAATACTA TTAATTTAAT CAAGAATAAA 
GGTCTCAGTG CACAGAAAAA GTTGAGTGAG GTAATCAGCT TTGAACCAGG AACATTGAGA 
CTGATCCGGC TGGTCAAGCT GAAAGAGGGA GACAGCATCA GCTTGGATAT AAATTACCAA 
AATCAATCCA TGAGCCTATT AGAAGATGAG TACCACACTT ACTGGGAAAT TATCTTGCTT 
AATGAAATAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019992.1
CDS	21..632
Translation	MTGQSNPRFRLLIGWCCLMSSALLMMTVYLATSSNKQSETNTTTSEHHSSAGPQEKRVQFSELQALNVIDYIRLLKDKKKIWICTQPCKSKRLKLNNSSVEIASTGLYHIHAQVGFKRHESTQETKKTPQKNTINLIKNKGLSAQKKLSEVISFEPGTLRLIRLVKLKEGDSISLDINYQNQSMSLLEDEYHTYWEIILLNEI

Target ORF information:

RefSeq Version	NM_001024821.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio lymphotoxin alpha (TNF superfamily, member 1) (lta), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024821.1

ORF Insert Sequence:

ATGACCGGCC AGAGTAACCC CAGGTTCCGC CTCCTGATTG GCTGGTGCTG CCTGATGAGC 
TCAGCTCTTT TGATGATGAC CGTATATCTC GCGACAAGTT CGAACAAACA GTCTGAAACA 
AACACGACAA CATCTGAACA CCACAGTTCA GCAGGACCTC AAGAAAAGAG AGTCCAATTT 
TCAGAACTTC AAGCTCTGAA TGTTATCGAC TACATCCGTC TGCTCAAAGA TAAGAAAAAA 
ATCTGGATAT GCACTCAACC ATGCAAAAGC AAAAGGCTTA AACTGAACAA CAGCAGCGTT 
GAAATTGCAA GCACTGGCCT GTACCACATT CATGCTCAGG TCGGCTTTAA GAGACATGAG 
AGCACGCAGG AAACAAAGAA GACTCCACAA AAAAATACTA TTAATTTAAT CAAGAATAAA 
GGTCTCAGTG CACAGAAAAA GTTGAGTGAG GTAATCAGCT TTGAACCAGG AACATTGAGA 
CTGATCCGGC TGGTCAAGCT GAAAGAGGGA GACAGCATCA GCTTGGATAT AAATTACCAA 
AATCAATCCA TGAGCCTATT AGAAGATGAG TACCACACTT ACTGGGAAAT TATCTTGCTT 
AATGAAATAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

lta ( XM_009291801.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_009290076.1 Danio rerio lymphotoxin alpha (TNF superfamily, member 1) (lta), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa36863
Clone ID Related Accession (Same CDS sequence)	XM_009291801.2 , XM_009291801.3 , NM_001024821.1
Accession Version	XM_009291801.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-23
Organism	Danio rerio(Zebrafish)
Product	lymphotoxin alpha isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007126.6) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_009291801.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCGGCC AGAGTAACCC CAGGTTCCGC CTCCTGATTG GCTGGTGCTG CCTGATGAGC 
TCAGCTCTTT TGATGATGAC CGTATATCTC GCGACAAGTT CGAACAAACA GTCTGAAACA 
AACACGACAA CATCTGAACA CCACAGTTCA GCAGGACCTC AAGAAAAGAG AGTCCAATTT 
TCAGAACTTC AAGCTCTGAA TGTTATCGAC TACATCCGTC TGCTCAAAGA TAAGAAAAAA 
ATCTGGATAT GCACTCAACC ATGCAAAAGC AAAAGGCTTA AACTGAACAA CAGCAGCGTT 
GAAATTGCAA GCACTGGCCT GTACCACATT CATGCTCAGG TCGGCTTTAA GAGACATGAG 
AGCACGCAGG AAACAAAGAA GACTCCACAA AAAAATACTA TTAATTTAAT CAAGAATAAA 
GGTCTCAGTG CACAGAAAAA GTTGAGTGAG GTAATCAGCT TTGAACCAGG AACATTGAGA 
CTGATCCGGC TGGTCAAGCT GAAAGAGGGA GACAGCATCA GCTTGGATAT AAATTACCAA 
AATCAATCCA TGAGCCTATT AGAAGATGAG TACCACACTT ACTGGGAAAT TATCTTGCTT 
AATGAAATAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_009290076.1
CDS	179..790
Translation	MTGQSNPRFRLLIGWCCLMSSALLMMTVYLATSSNKQSETNTTTSEHHSSAGPQEKRVQFSELQALNVIDYIRLLKDKKKIWICTQPCKSKRLKLNNSSVEIASTGLYHIHAQVGFKRHESTQETKKTPQKNTINLIKNKGLSAQKKLSEVISFEPGTLRLIRLVKLKEGDSISLDINYQNQSMSLLEDEYHTYWEIILLNEI

Target ORF information:

RefSeq Version	XM_009291801.2
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio lymphotoxin alpha (TNF superfamily, member 1) (lta), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_009291801.2

ORF Insert Sequence:

ATGACCGGCC AGAGTAACCC CAGGTTCCGC CTCCTGATTG GCTGGTGCTG CCTGATGAGC 
TCAGCTCTTT TGATGATGAC CGTATATCTC GCGACAAGTT CGAACAAACA GTCTGAAACA 
AACACGACAA CATCTGAACA CCACAGTTCA GCAGGACCTC AAGAAAAGAG AGTCCAATTT 
TCAGAACTTC AAGCTCTGAA TGTTATCGAC TACATCCGTC TGCTCAAAGA TAAGAAAAAA 
ATCTGGATAT GCACTCAACC ATGCAAAAGC AAAAGGCTTA AACTGAACAA CAGCAGCGTT 
GAAATTGCAA GCACTGGCCT GTACCACATT CATGCTCAGG TCGGCTTTAA GAGACATGAG 
AGCACGCAGG AAACAAAGAA GACTCCACAA AAAAATACTA TTAATTTAAT CAAGAATAAA 
GGTCTCAGTG CACAGAAAAA GTTGAGTGAG GTAATCAGCT TTGAACCAGG AACATTGAGA 
CTGATCCGGC TGGTCAAGCT GAAAGAGGGA GACAGCATCA GCTTGGATAT AAATTACCAA 
AATCAATCCA TGAGCCTATT AGAAGATGAG TACCACACTT ACTGGGAAAT TATCTTGCTT 
AATGAAATAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

lta ( XM_009291801.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_009290076.1 Danio rerio lymphotoxin alpha (TNF superfamily, member 1) (lta), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa36863
Clone ID Related Accession (Same CDS sequence)	XM_009291801.2 , XM_009291801.3 , NM_001024821.1
Accession Version	XM_009291801.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-14
Organism	Danio rerio(zebrafish)
Product	lymphotoxin alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007126.7) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XM_009291801.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCGGCC AGAGTAACCC CAGGTTCCGC CTCCTGATTG GCTGGTGCTG CCTGATGAGC 
TCAGCTCTTT TGATGATGAC CGTATATCTC GCGACAAGTT CGAACAAACA GTCTGAAACA 
AACACGACAA CATCTGAACA CCACAGTTCA GCAGGACCTC AAGAAAAGAG AGTCCAATTT 
TCAGAACTTC AAGCTCTGAA TGTTATCGAC TACATCCGTC TGCTCAAAGA TAAGAAAAAA 
ATCTGGATAT GCACTCAACC ATGCAAAAGC AAAAGGCTTA AACTGAACAA CAGCAGCGTT 
GAAATTGCAA GCACTGGCCT GTACCACATT CATGCTCAGG TCGGCTTTAA GAGACATGAG 
AGCACGCAGG AAACAAAGAA GACTCCACAA AAAAATACTA TTAATTTAAT CAAGAATAAA 
GGTCTCAGTG CACAGAAAAA GTTGAGTGAG GTAATCAGCT TTGAACCAGG AACATTGAGA 
CTGATCCGGC TGGTCAAGCT GAAAGAGGGA GACAGCATCA GCTTGGATAT AAATTACCAA 
AATCAATCCA TGAGCCTATT AGAAGATGAG TACCACACTT ACTGGGAAAT TATCTTGCTT 
AATGAAATAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_009290076.1
CDS	175..786
Translation	MTGQSNPRFRLLIGWCCLMSSALLMMTVYLATSSNKQSETNTTTSEHHSSAGPQEKRVQFSELQALNVIDYIRLLKDKKKIWICTQPCKSKRLKLNNSSVEIASTGLYHIHAQVGFKRHESTQETKKTPQKNTINLIKNKGLSAQKKLSEVISFEPGTLRLIRLVKLKEGDSISLDINYQNQSMSLLEDEYHTYWEIILLNEI

Target ORF information:

RefSeq Version	XM_009291801.3
Organism	Danio rerio(zebrafish)
Definition	Danio rerio lymphotoxin alpha (TNF superfamily, member 1) (lta), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_009291801.3

ORF Insert Sequence:

ATGACCGGCC AGAGTAACCC CAGGTTCCGC CTCCTGATTG GCTGGTGCTG CCTGATGAGC 
TCAGCTCTTT TGATGATGAC CGTATATCTC GCGACAAGTT CGAACAAACA GTCTGAAACA 
AACACGACAA CATCTGAACA CCACAGTTCA GCAGGACCTC AAGAAAAGAG AGTCCAATTT 
TCAGAACTTC AAGCTCTGAA TGTTATCGAC TACATCCGTC TGCTCAAAGA TAAGAAAAAA 
ATCTGGATAT GCACTCAACC ATGCAAAAGC AAAAGGCTTA AACTGAACAA CAGCAGCGTT 
GAAATTGCAA GCACTGGCCT GTACCACATT CATGCTCAGG TCGGCTTTAA GAGACATGAG 
AGCACGCAGG AAACAAAGAA GACTCCACAA AAAAATACTA TTAATTTAAT CAAGAATAAA 
GGTCTCAGTG CACAGAAAAA GTTGAGTGAG GTAATCAGCT TTGAACCAGG AACATTGAGA 
CTGATCCGGC TGGTCAAGCT GAAAGAGGGA GACAGCATCA GCTTGGATAT AAATTACCAA 
AATCAATCCA TGAGCCTATT AGAAGATGAG TACCACACTT ACTGGGAAAT TATCTTGCTT 
AATGAAATAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hepatotoxicity of benzotriazole and its effect on the cadmium induced toxicity in zebrafish Danio rerio.
Environmental pollution (Barking, Essex : 1987)224706-713(2017 May)
Duan Z,Xing Y,Feng Z,Zhang H,Li C,Gong Z,Wang L,Sun H

Transcriptome profiling analysis of naked carp (Gymnocypris przewalskii) provides insights into the immune-related genes in highland fish.
Fish & shellfish immunology46(2)366-77(2015 Oct)
Tong C,Zhang C,Zhang R,Zhao K

Evolutionary evidence of tumor necrosis factor super family members in the Japanese pufferfish (Takifugu rubripes): Comprehensive genomic identification and expression analysis.
Marine genomics2225-36(2015 Aug)
Biswas G,Kinoshita S,Kono T,Hikima J,Sakai M

The proprotein convertase subtilisin/kexin furinA regulates zebrafish host response against Mycobacterium marinum.
Infection and immunity83(4)1431-42(2015 Apr)
Ojanen MJ,Turpeinen H,Cordova ZM,Hammar?n MM,Harjula SK,Parikka M,R?met M,Pesu M

Presence of two tumor necrosis factor (tnf)-? homologs on different chromosomes of zebrafish (Danio rerio) and medaka (Oryzias latipes).
Marine genomics131-9(2014 Feb)
Kinoshita S,Biswas G,Kono T,Hikima J,Sakai M