apobec2a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	apobec2a
Entrez Gene ID	503736
Full Name	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a
Synonyms	zgc:110762
General protein information	Preferred Names apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a Names apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a apo2a apolipoprotein B-editing catalytic subunit 2a
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001013314.2	NP_001013332.1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a

Pathways from BioSystems

Homologies

	APOBEC2	XP_001117195.1
Bos taurus (cattle)	APOBEC2	NP_001029527.1
Rattus norvegicus (Norway rat)	Apobec2	NP_001100353.1
Pan troglodytes (chimpanzee)	APOBEC2	XP_003311341.1
Canis lupus familiaris (dog)	APOBEC2	XP_538909.2
Mus musculus (house mouse)	Apobec2	NP_033824.1
Gallus gallus (chicken)	APOBEC2	XP_418038.1
Xenopus tropicalis (tropical clawed frog)	apobec2	NP_001006722.1
Homo sapiens (human)	APOBEC2	NP_006780.1
Danio rerio (zebrafish)	LOC567047	NP_001161935.1
Danio rerio (zebrafish)	apobec2a	NP_001013332.1

Gene Ontology
Bibliography

Related articles in PubMed

Parental vitamin deficiency affects the embryonic gene expression of immune-, lipid transport- and apolipoprotein genes.
Skj?rven KH, Jakt LM, Dahl JA, Espe M, Aanes H, Hamre K, Fernandes JM
Scientific reports634535(2016 Oct)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Eumetazoan cryptochrome phylogeny and evolution.
Haug MF, Gesemann M, Lazovi? V, Neuhauss SC
Genome biology and evolution7(2)601-19(2015 Jan)

Zinc-binding domain-dependent, deaminase-independent actions of apolipoprotein B mRNA-editing enzyme, catalytic polypeptide 2 (Apobec2), mediate its effect on zebrafish retina regeneration.
Powell C, Cornblath E, Goldman D
The Journal of biological chemistry289(42)28924-41(2014 Oct)

No evidence for AID/MBD4-coupled DNA demethylation in zebrafish embryos.
Shimoda N, Hirose K, Kaneto R, Izawa T, Yokoi H, Hashimoto N, Kikuchi Y
PloS one9(12)e114816(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The data of this study demonistrated that the apobec2a is essential for retina and optic nerve regeneration.
Title: Injury-dependent M?ller glia and ganglion cell reprogramming during tissue regeneration requires Apobec2a and Apobec2b.

The following apobec2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the apobec2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa31735	NM_001013314.2 Latest version!	Danio rerio apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a (apobec2a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

apobec2a ( NM_001013314.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001013332.1 Danio rerio apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a (apobec2a), mRNA.

Price & Availability↑

CloneID	ODa31735
Clone ID Related Accession (Same CDS sequence)	NM_001013314.2
Accession Version	NM_001013314.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 750bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-08-05
Organism	Danio rerio(zebrafish)
Product	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC090758.1. On Aug 30, 2012 this sequence version replaced NM_001013314.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC090758.1, EH578854.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168447, SAMEA2168448 [ECO:0000348] ##Evidence-Data-END##

ATGGCCGATA GAAAGGGCAG CAGCGGCGTC AGCTCTCGTC TGAGCGTCAG GAGGAAGGAA 
AAGGCAGAAA ATGATGCCAA GAAAGAGGAG AAAAGCCCAA CAGAAGCGGA GAAACCCGAA 
GTGAATGGGA AAGAAGTGCC GATGGAGAAC GGAGAGGCCG GAGCTGCTGC TGCAGACGGA 
GAAAAACCAG AACCTATAGA GCTGCCGCCG TTCGAGACCA TCACAGGGGA TCGCATGGAC 
CCGTTTTTCT TCAAGTTCCA GTTCAAGAAC GTGGAGTACT CGTCCGGCCG GAATAAAACC 
TTCCTGTGTT ACCTGGTGGA CCACGGCGGC GAAGGCCTGA TGAGGGGCTA CATTGAGGAC 
GAGCACGCTG GCGGACACGC AGAGGAAGCC TTTTTCCAGC AGATCCTGAC CAACTACGAC 
CCGGCCTGCA AATACACCAT CACCTGGTAC ATGTCCTCCA GTCCCTGCGC CAACTGCGCA 
ACCAAGCTGG CGGAGATCCT GCGCTCCAGG AAGAACATCC GGCTGGCCAT CTTTTCGTCG 
CGGCTGTTCG AGTGGGAGGA GCCTGAGATC CAGGCAGGGC TGAAGCTACT AGCGTCCGTC 
GGCTGCAAAC TGCGCATGAT GAAGCCGCTG GATTTCACCT ACACCTGGGA CACGTTCGTG 
GAGAGCGACG AACAGCAGTT CACACCCTGG GAGGACTGTC AGGAGAACTA CGAGTACTAC 
CAGGACAAAC TGGCCGACAT CCTGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013332.1
CDS	11..760
Translation	MADRKGSSGVSSRLSVRRKEKAENDAKKEEKSPTEAEKPEVNGKEVPMENGEAGAAAADGEKPEPIELPPFETITGDRMDPFFFKFQFKNVEYSSGRNKTFLCYLVDHGGEGLMRGYIEDEHAGGHAEEAFFQQILTNYDPACKYTITWYMSSSPCANCATKLAEILRSRKNIRLAIFSSRLFEWEEPEIQAGLKLLASVGCKLRMMKPLDFTYTWDTFVESDEQQFTPWEDCQENYEYYQDKLADILQ

Target ORF information:

RefSeq Version	NM_001013314.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a (apobec2a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013314.2

ORF Insert Sequence:

ATGGCCGATA GAAAGGGCAG CAGCGGCGTC AGCTCTCGTC TGAGCGTCAG GAGGAAGGAA 
AAGGCAGAAA ATGATGCCAA GAAAGAGGAG AAAAGCCCAA CAGAAGCGGA GAAACCCGAA 
GTGAATGGGA AAGAAGTGCC GATGGAGAAC GGAGAGGCCG GAGCTGCTGC TGCAGACGGA 
GAAAAACCAG AACCTATAGA GCTGCCGCCG TTCGAGACCA TCACAGGGGA TCGCATGGAC 
CCGTTTTTCT TCAAGTTCCA GTTCAAGAAC GTGGAGTACT CGTCCGGCCG GAATAAAACC 
TTCCTGTGTT ACCTGGTGGA CCACGGCGGC GAAGGCCTGA TGAGGGGCTA CATTGAGGAC 
GAGCACGCTG GCGGACACGC AGAGGAAGCC TTTTTCCAGC AGATCCTGAC CAACTACGAC 
CCGGCCTGCA AATACACCAT CACCTGGTAC ATGTCCTCCA GTCCCTGCGC CAACTGCGCA 
ACCAAGCTGG CGGAGATCCT GCGCTCCAGG AAGAACATCC GGCTGGCCAT CTTTTCGTCG 
CGGCTGTTCG AGTGGGAGGA GCCTGAGATC CAGGCAGGGC TGAAGCTACT AGCGTCCGTC 
GGCTGCAAAC TGCGCATGAT GAAGCCGCTG GATTTCACCT ACACCTGGGA CACGTTCGTG 
GAGAGCGACG AACAGCAGTT CACACCCTGG GAGGACTGTC AGGAGAACTA CGAGTACTAC 
CAGGACAAAC TGGCCGACAT CCTGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Parental vitamin deficiency affects the embryonic gene expression of immune-, lipid transport- and apolipoprotein genes.
Scientific reports634535(2016 Oct)
Skj?rven KH,Jakt LM,Dahl JA,Espe M,Aanes H,Hamre K,Fernandes JM

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Eumetazoan cryptochrome phylogeny and evolution.
Genome biology and evolution7(2)601-19(2015 Jan)
Haug MF,Gesemann M,Lazovi? V,Neuhauss SC

Zinc-binding domain-dependent, deaminase-independent actions of apolipoprotein B mRNA-editing enzyme, catalytic polypeptide 2 (Apobec2), mediate its effect on zebrafish retina regeneration.
The Journal of biological chemistry289(42)28924-41(2014 Oct)
Powell C,Cornblath E,Goldman D

No evidence for AID/MBD4-coupled DNA demethylation in zebrafish embryos.
PloS one9(12)e114816(2014)
Shimoda N,Hirose K,Kaneto R,Izawa T,Yokoi H,Hashimoto N,Kikuchi Y