ildr1a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	ildr1a
Entrez Gene ID	393364
Full Name	immunoglobulin-like domain containing receptor 1a
Synonyms	zgc:64227
General protein information	Preferred Names immunoglobulin-like domain containing receptor 1a Names immunoglobulin-like domain containing receptor 1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_200393.1	NP_956687.1	immunoglobulin-like domain containing receptor 1 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Ildr1	NP_001272717.1
Rattus norvegicus (Norway rat)	Ildr1	NP_001121008.2
Canis lupus familiaris (dog)	ILDR1	XP_005639611.1
Homo sapiens (human)	ILDR1	NP_001186728.1
Pan troglodytes (chimpanzee)	ILDR1	XP_526282.3
	ILDR1	XP_001111791.1
Danio rerio (zebrafish)	ildr1b	NP_001004642.1
Danio rerio (zebrafish)	ildr1a	NP_956687.1
Xenopus tropicalis (tropical clawed frog)	LOC100486057	XP_002940967.1
Bos taurus (cattle)	ILDR1	NP_001095684.1
Gallus gallus (chicken)	ILDR1	XP_004938277.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.
Varshney GK, Pei W, LaFave MC, Idol J, Xu L, Gallardo V, Carrington B, Bishop K, Jones M, Li M, Harper U, Huang SC, Prakash A, Chen W, Sood R, Ledin J, Burgess SM
Genome research25(7)1030-42(2015 Jul)

Ildr1b is essential for semicircular canal development, migration of the posterior lateral line primordium and hearing ability in zebrafish: implications for a role in the recessive hearing impairment DFNB42.
Sang Q, Zhang J, Feng R, Wang X, Li Q, Zhao X, Xing Q, Chen W, Du J, Sun S, Chai R, Liu D, Jin L, He L, Li H, Wang L
Human molecular genetics23(23)6201-11(2014 Dec)

Loss-of-function mutations of ILDR1 cause autosomal-recessive hearing impairment DFNB42.
Borck G, Ur Rehman A, Lee K, Pogoda HM, Kakar N, von Ameln S, Grillet N, Hildebrand MS, Ahmed ZM, N?rnberg G, Ansar M, Basit S, Javed Q, Morell RJ, Nasreen N, Shearer AE, Ahmad A, Kahrizi K, Shaikh RS, Ali RA, Khan SN, Goebel I, Meyer NC, Kimberling WJ, Webster JA, Stephan DA, Schiller MR, Bahlo M, Najmabadi H, Gillespie PG, N?rnberg P, Wollnik B, Riazuddin S, Smith RJ, Ahmad W, M?ller U, Hammerschmidt M, Friedman TB, Riazuddin S, Leal SM, Ahmad J, Kubisch C
American journal of human genetics88(2)127-37(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ildr1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ildr1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa34801	NM_200393.1 Latest version!	Danio rerio immunoglobulin-like domain containing receptor 1a (ildr1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ildr1a ( NM_200393.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_956687.1 Danio rerio immunoglobulin-like domain containing receptor 1a (ildr1a), mRNA.

Price & Availability↑

CloneID	ODa34801
Clone ID Related Accession (Same CDS sequence)	NM_200393.1
Accession Version	NM_200393.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-07
Organism	Danio rerio(zebrafish)
Product	immunoglobulin-like domain containing receptor 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC053314.1. ##Evidence-Data-START## Transcript exon combination :: BC053314.1, CU458974.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGATGAGGG GAATGATCAG GTGTGTGCTG CTGCTGCTGA GTGTGCTGAT CTCAGATGTT 
ATGTCTATCC AGGTGATTCT GACCAATCAG CAGATGAGCA CGACTCTGTT CGCCACGGTG 
ACGCTGCGCT GTGATTACTC CACCTCCGCT CAGCTGCAGA ATGTTCTGGT CACCTGGGTT 
TACAAGTCCT TCTGCAAAGA CCCTGTTCTG GACTACTACT CTGCAGCGTA TCAGTCTGCT 
CTGCAGCTGG GTCAGAACCC CGCCAATGAC TGCACGGACT CGCAGCGCAC CATCCGGACA 
GTGGCTCAGA AACTGGGCAC TAATGAGGCG GTGCTGGGGG CCGAATACCG GGACCGCAAG 
ATCTACATCC AGAACAAGGC GGACCTGGTG ATCCAAGAGG TGATGTGGTG GGATAACGGT 
GTGTATTACT GTAAAGTGGA CGCGCCCGGA GACACCATCG GAGACCCAGA CAAGGAGATG 
AACCTCATCG TCTACAACTG GCTGACGGTG CTCCTGATAC TCATCGGTGC GCTGCTCCTC 
ATCATCCTCT TCTGCATCTG CTGCTGCCAG TGCTGCCCAC AGAAGTGCTG CTGTTACGTG 
CGCTGCCCGT GCTGCCCGCA GACCTGCTGC TGCCCGGAGA AAGCTGTGAT GCAGCACCGG 
CTGATGAAGG AGGCGCAGAG GGCCATGACG CCCTGGATGA ACGGGCAGCC GCTGTACGCC 
CCCATGAGCA ACCACAGCTC CAGCTACCAG ATGAACCCGC TGCTGTACGC AGGCTCCACC 
GCAGGTAAGG GCCCCATGAC GCCACTGCCG CTGCCGCCTC CGCAGATGCC CGTCACACAG 
ATGCCCCTCA TGCAGATGCC TCCTCCCAGC ATGCACGGCA ATGGCAGCGC CCATGGCACC 
AATCAGGTCC TGGACTACCT GGAGAACCAG ATGCGGGGCA TAGACGTGAA CAGCCCGCTC 
CTGCCCCCTC CACCGCAGCA TGTGCCCCAG CACGTGCCCT TCTCCGCCGG GCCACCCAGC 
ATGCTCTCTG GGCTGGAGGA TGTCCCCGCG AAGCGTCCCC GTGGCCACCC GCACGCAAAC 
TCCAGCGGCT CCTCAGCGTA CGGCCCACGC CGCGGCCCCC CCACCTCGCT GCCGCGCAGC 
TACAGCCAGG AGGATGTGTT GGAGGGCCGC AGGGGCGCCG GAGCTCACAG ACCCCGCTCG 
CGCTCCAGAG ACGACCTGCT GCACACCGGC CCCCAGTACA GTCCGGCCCG CCGCGGCTCC 
TGGAGCTCCA CTGATGAGGG CAGCCGGCGC GGGCCATGGG GGGGCAGGGA GTACGAGCCC 
GGGAAGAAGC CAGCGAAGCG ACCCGAAAGA TTCTCTGATA AGGGCTCTCG CAGTGGAAAC 
AGCATCATCA TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_956687.1
CDS	140..1534
Translation	MMRGMIRCVLLLLSVLISDVMSIQVILTNQQMSTTLFATVTLRCDYSTSAQLQNVLVTWVYKSFCKDPVLDYYSAAYQSALQLGQNPANDCTDSQRTIRTVAQKLGTNEAVLGAEYRDRKIYIQNKADLVIQEVMWWDNGVYYCKVDAPGDTIGDPDKEMNLIVYNWLTVLLILIGALLLIILFCICCCQCCPQKCCCYVRCPCCPQTCCCPEKAVMQHRLMKEAQRAMTPWMNGQPLYAPMSNHSSSYQMNPLLYAGSTAGKGPMTPLPLPPPQMPVTQMPLMQMPPPSMHGNGSAHGTNQVLDYLENQMRGIDVNSPLLPPPPQHVPQHVPFSAGPPSMLSGLEDVPAKRPRGHPHANSSGSSAYGPRRGPPTSLPRSYSQEDVLEGRRGAGAHRPRSRSRDDLLHTGPQYSPARRGSWSSTDEGSRRGPWGGREYEPGKKPAKRPERFSDKGSRSGNSIII

Target ORF information:

RefSeq Version	NM_200393.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio immunoglobulin-like domain containing receptor 1a (ildr1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_200393.1

ORF Insert Sequence:

ATGATGAGGG GAATGATCAG GTGTGTGCTG CTGCTGCTGA GTGTGCTGAT CTCAGATGTT 
ATGTCTATCC AGGTGATTCT GACCAATCAG CAGATGAGCA CGACTCTGTT CGCCACGGTG 
ACGCTGCGCT GTGATTACTC CACCTCCGCT CAGCTGCAGA ATGTTCTGGT CACCTGGGTT 
TACAAGTCCT TCTGCAAAGA CCCTGTTCTG GACTACTACT CTGCAGCGTA TCAGTCTGCT 
CTGCAGCTGG GTCAGAACCC CGCCAATGAC TGCACGGACT CGCAGCGCAC CATCCGGACA 
GTGGCTCAGA AACTGGGCAC TAATGAGGCG GTGCTGGGGG CCGAATACCG GGACCGCAAG 
ATCTACATCC AGAACAAGGC GGACCTGGTG ATCCAAGAGG TGATGTGGTG GGATAACGGT 
GTGTATTACT GTAAAGTGGA CGCGCCCGGA GACACCATCG GAGACCCAGA CAAGGAGATG 
AACCTCATCG TCTACAACTG GCTGACGGTG CTCCTGATAC TCATCGGTGC GCTGCTCCTC 
ATCATCCTCT TCTGCATCTG CTGCTGCCAG TGCTGCCCAC AGAAGTGCTG CTGTTACGTG 
CGCTGCCCGT GCTGCCCGCA GACCTGCTGC TGCCCGGAGA AAGCTGTGAT GCAGCACCGG 
CTGATGAAGG AGGCGCAGAG GGCCATGACG CCCTGGATGA ACGGGCAGCC GCTGTACGCC 
CCCATGAGCA ACCACAGCTC CAGCTACCAG ATGAACCCGC TGCTGTACGC AGGCTCCACC 
GCAGGTAAGG GCCCCATGAC GCCACTGCCG CTGCCGCCTC CGCAGATGCC CGTCACACAG 
ATGCCCCTCA TGCAGATGCC TCCTCCCAGC ATGCACGGCA ATGGCAGCGC CCATGGCACC 
AATCAGGTCC TGGACTACCT GGAGAACCAG ATGCGGGGCA TAGACGTGAA CAGCCCGCTC 
CTGCCCCCTC CACCGCAGCA TGTGCCCCAG CACGTGCCCT TCTCCGCCGG GCCACCCAGC 
ATGCTCTCTG GGCTGGAGGA TGTCCCCGCG AAGCGTCCCC GTGGCCACCC GCACGCAAAC 
TCCAGCGGCT CCTCAGCGTA CGGCCCACGC CGCGGCCCCC CCACCTCGCT GCCGCGCAGC 
TACAGCCAGG AGGATGTGTT GGAGGGCCGC AGGGGCGCCG GAGCTCACAG ACCCCGCTCG 
CGCTCCAGAG ACGACCTGCT GCACACCGGC CCCCAGTACA GTCCGGCCCG CCGCGGCTCC 
TGGAGCTCCA CTGATGAGGG CAGCCGGCGC GGGCCATGGG GGGGCAGGGA GTACGAGCCC 
GGGAAGAAGC CAGCGAAGCG ACCCGAAAGA TTCTCTGATA AGGGCTCTCG CAGTGGAAAC 
AGCATCATCA TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.
Genome research25(7)1030-42(2015 Jul)
Varshney GK,Pei W,LaFave MC,Idol J,Xu L,Gallardo V,Carrington B,Bishop K,Jones M,Li M,Harper U,Huang SC,Prakash A,Chen W,Sood R,Ledin J,Burgess SM

Ildr1b is essential for semicircular canal development, migration of the posterior lateral line primordium and hearing ability in zebrafish: implications for a role in the recessive hearing impairment DFNB42.
Human molecular genetics23(23)6201-11(2014 Dec)
Sang Q,Zhang J,Feng R,Wang X,Li Q,Zhao X,Xing Q,Chen W,Du J,Sun S,Chai R,Liu D,Jin L,He L,Li H,Wang L

Loss-of-function mutations of ILDR1 cause autosomal-recessive hearing impairment DFNB42.
American journal of human genetics88(2)127-37(2011 Feb)
Borck G,Ur Rehman A,Lee K,Pogoda HM,Kakar N,von Ameln S,Grillet N,Hildebrand MS,Ahmed ZM,N?rnberg G,Ansar M,Basit S,Javed Q,Morell RJ,Nasreen N,Shearer AE,Ahmad A,Kahrizi K,Shaikh RS,Ali RA,Khan SN,Goebel I,Meyer NC,Kimberling WJ,Webster JA,Stephan DA,Schiller MR,Bahlo M,Najmabadi H,Gillespie PG,N?rnberg P,Wollnik B,Riazuddin S,Smith RJ,Ahmad W,M?ller U,Hammerschmidt M,Friedman TB,Riazuddin S,Leal SM,Ahmad J,Kubisch C

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ildr1a cDNA ORF clone, Danio rerio(zebrafish)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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