pah cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	pah
Entrez Gene ID	378962
Full Name	phenylalanine hydroxylase
Synonyms	cb877,wu:fb02f10,zgc:65981
General protein information	Preferred Names phenylalanine hydroxylase Names phenylalanine-4-hydroxylase
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_200551.1	NP_956845.1	phenylalanine-4-hydroxylase

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PAH	XP_001156919.1
Rattus norvegicus (Norway rat)	Pah	NP_036751.2
Danio rerio (zebrafish)	pah	NP_956845.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005712	XP_315722.4
Caenorhabditis elegans (roundworm)	pah-1	NP_001254185.1
Xenopus tropicalis (tropical clawed frog)	pah	NP_001027484.1
Bos taurus (cattle)	PAH	NP_001039523.1
Mus musculus (house mouse)	Pah	NP_032803.2
	PAH	XP_001094859.1
Canis lupus familiaris (dog)	PAH	XP_532671.3
Homo sapiens (human)	PAH	NP_000268.1
Gallus gallus (chicken)	PAH	NP_001001298.1
Drosophila melanogaster (fruit fly)	Hn	NP_001261542.1

Gene Ontology
Bibliography

Related articles in PubMed

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Dynamic gene expression by putative hair-cell progenitors during regeneration in the zebrafish lateral line.
Steiner AB, Kim T, Cabot V, Hudspeth AJ
Proceedings of the National Academy of Sciences of the United States of America111(14)E1393-401(2014 Apr)

Zebrafish tyrosine hydroxylase 2 gene encodes tryptophan hydroxylase.
Ren G, Li S, Zhong H, Lin S
The Journal of biological chemistry288(31)22451-9(2013 Aug)

Transcriptome profiling of zebrafish infected with Streptococcus suis.
Wu Z, Zhang W, Lu Y, Lu C
Microbial pathogenesis48(5)178-87(2010 May)

Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology.
Lam SH, Mathavan S, Tong Y, Li H, Karuturi RK, Wu Y, Vega VB, Liu ET, Gong Z
PLoS genetics4(7)e1000121(2008 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following pah gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pah cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa37110	NM_200551.1 Latest version!	Danio rerio phenylalanine hydroxylase (pah), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

pah ( NM_200551.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_956845.1 Danio rerio phenylalanine hydroxylase (pah), mRNA.

Price & Availability↑

CloneID	ODa37110
Clone ID Related Accession (Same CDS sequence)	NM_200551.1
Accession Version	NM_200551.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1350bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	phenylalanine-4-hydroxylase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC056537.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC056537.1, BC064329.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGGACGCAG GACTCACTCA GATAAACGGG GGATTGGAGA GAAAGGGCTC TCTGACCTCA 
TCCTACCTGG AAGAACCATT AAACAAATCA GGAGTGGTGT CCTGCATTTT CTCTCTGAAG 
GAAGAAGTTG GAGCTCTCGT GGAAGCTCTG AAACTATTTG AGGAGAAAGG CATTAACCTG 
ACGCACATTG AGTCCCGTCC ATCACGCAAG AACAATGAAG AGTACGAGTT CTTCATCAGC 
GTGGATCAAG CCTCCTCTAA AGTTCTGGAT GAAATCGTTG ATGGTCTTCG CACCCAGATC 
AGGGGCCAAG TTCACGAGCT ATCCCGCAAC AAACAGAAAG ACACAGTCCC ATGGTTCCCC 
AATGACATCC AGGACTTGGA CCGATTTGCC AACCAAATCC TGAGTTATGG ATCCGAGCTG 
GACGCAGACC ATCCAGGTTT CACTGACACC GTCTACCGGG CCAGGAGGAA GGAATTTGCT 
GACATTGCTT ACAACTACAG ACATGGACAG CCTATTCCAC GTGTTGAATA CACAGCTGAA 
GAGAAGGCCA CATGGGGGAC AGTTTTCAGA GAGCTGAAGA CTCTGTACCC CACACATGCC 
TGCCGTGAAC ACAACCGTGT CTTTCCGCTG CTTGAGAAAT ACTGTGGGTA TCGTGAGGAC 
AACATCCCAC AGCTGGAGGA CATCTCACAC TACCTGCAAT CATGCACAGG TTTCCGTCTG 
CGTCCTGTGG CCGGTCTCCT CTCCTCAAGG GACTTCTTAG CTGGTCTGGC CTTTCGAGTG 
TTTCACTCGA CCCAGTACAT TCGCCACAGC TCCAAACCCA TGTACACACC TGAGCCGGAT 
ATCTGTCATG AGCTGCTGGG TCATGTGCCG TTGTTTGCTG ACCCAAATTT TGCCCAGTTC 
TCTCAGGAAA TTGGGCTCGC TTCTCTGGGC GCCCCTGATG AGTTCATAGA GAAGCTGGCT 
ACAGTCTACT GGTTCACTGT GGAATTTGGT CTGTGCAAGC AAGGAAATGA AGTGAAGGCT 
TATGGTGCAG GTCTGCTGTC ATCCTTTGGT GAACTGCAGT ACTGTCTGAC GAACGAGCCT 
AAACTTCAGC CCTTTGAGCC AGAGAAGACC TGCCAGCAGA AGTATCCTAT TACGGAGTTC 
CAGCCCGTTT ACTTTGTGGC AGAAAGTTTT GAAGACGCCA AAGAGAAAGT CCGGAGATTT 
GCCACTACCA TCCCCAGGCC TTTCTCTGTA CGCTATAATG CATACACACA GAGAATTGAG 
ATGCTGGACA ATGCACAACA GCTGAAGAAC CTGGCTGACA GCATCAATGG TGAGATCTCA 
ATCCTGTGCA ATGCCCTGCG GAAGATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_956845.1
CDS	36..1385
Translation	MDAGLTQINGGLERKGSLTSSYLEEPLNKSGVVSCIFSLKEEVGALVEALKLFEEKGINLTHIESRPSRKNNEEYEFFISVDQASSKVLDEIVDGLRTQIRGQVHELSRNKQKDTVPWFPNDIQDLDRFANQILSYGSELDADHPGFTDTVYRARRKEFADIAYNYRHGQPIPRVEYTAEEKATWGTVFRELKTLYPTHACREHNRVFPLLEKYCGYREDNIPQLEDISHYLQSCTGFRLRPVAGLLSSRDFLAGLAFRVFHSTQYIRHSSKPMYTPEPDICHELLGHVPLFADPNFAQFSQEIGLASLGAPDEFIEKLATVYWFTVEFGLCKQGNEVKAYGAGLLSSFGELQYCLTNEPKLQPFEPEKTCQQKYPITEFQPVYFVAESFEDAKEKVRRFATTIPRPFSVRYNAYTQRIEMLDNAQQLKNLADSINGEISILCNALRKM

Target ORF information:

RefSeq Version	NM_200551.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio phenylalanine hydroxylase (pah), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_200551.1

ORF Insert Sequence:

ATGGACGCAG GACTCACTCA GATAAACGGG GGATTGGAGA GAAAGGGCTC TCTGACCTCA 
TCCTACCTGG AAGAACCATT AAACAAATCA GGAGTGGTGT CCTGCATTTT CTCTCTGAAG 
GAAGAAGTTG GAGCTCTCGT GGAAGCTCTG AAACTATTTG AGGAGAAAGG CATTAACCTG 
ACGCACATTG AGTCCCGTCC ATCACGCAAG AACAATGAAG AGTACGAGTT CTTCATCAGC 
GTGGATCAAG CCTCCTCTAA AGTTCTGGAT GAAATCGTTG ATGGTCTTCG CACCCAGATC 
AGGGGCCAAG TTCACGAGCT ATCCCGCAAC AAACAGAAAG ACACAGTCCC ATGGTTCCCC 
AATGACATCC AGGACTTGGA CCGATTTGCC AACCAAATCC TGAGTTATGG ATCCGAGCTG 
GACGCAGACC ATCCAGGTTT CACTGACACC GTCTACCGGG CCAGGAGGAA GGAATTTGCT 
GACATTGCTT ACAACTACAG ACATGGACAG CCTATTCCAC GTGTTGAATA CACAGCTGAA 
GAGAAGGCCA CATGGGGGAC AGTTTTCAGA GAGCTGAAGA CTCTGTACCC CACACATGCC 
TGCCGTGAAC ACAACCGTGT CTTTCCGCTG CTTGAGAAAT ACTGTGGGTA TCGTGAGGAC 
AACATCCCAC AGCTGGAGGA CATCTCACAC TACCTGCAAT CATGCACAGG TTTCCGTCTG 
CGTCCTGTGG CCGGTCTCCT CTCCTCAAGG GACTTCTTAG CTGGTCTGGC CTTTCGAGTG 
TTTCACTCGA CCCAGTACAT TCGCCACAGC TCCAAACCCA TGTACACACC TGAGCCGGAT 
ATCTGTCATG AGCTGCTGGG TCATGTGCCG TTGTTTGCTG ACCCAAATTT TGCCCAGTTC 
TCTCAGGAAA TTGGGCTCGC TTCTCTGGGC GCCCCTGATG AGTTCATAGA GAAGCTGGCT 
ACAGTCTACT GGTTCACTGT GGAATTTGGT CTGTGCAAGC AAGGAAATGA AGTGAAGGCT 
TATGGTGCAG GTCTGCTGTC ATCCTTTGGT GAACTGCAGT ACTGTCTGAC GAACGAGCCT 
AAACTTCAGC CCTTTGAGCC AGAGAAGACC TGCCAGCAGA AGTATCCTAT TACGGAGTTC 
CAGCCCGTTT ACTTTGTGGC AGAAAGTTTT GAAGACGCCA AAGAGAAAGT CCGGAGATTT 
GCCACTACCA TCCCCAGGCC TTTCTCTGTA CGCTATAATG CATACACACA GAGAATTGAG 
ATGCTGGACA ATGCACAACA GCTGAAGAAC CTGGCTGACA GCATCAATGG TGAGATCTCA 
ATCCTGTGCA ATGCCCTGCG GAAGATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Dynamic gene expression by putative hair-cell progenitors during regeneration in the zebrafish lateral line.
Proceedings of the National Academy of Sciences of the United States of America111(14)E1393-401(2014 Apr)
Steiner AB,Kim T,Cabot V,Hudspeth AJ

Zebrafish tyrosine hydroxylase 2 gene encodes tryptophan hydroxylase.
The Journal of biological chemistry288(31)22451-9(2013 Aug)
Ren G,Li S,Zhong H,Lin S

Transcriptome profiling of zebrafish infected with Streptococcus suis.
Microbial pathogenesis48(5)178-87(2010 May)
Wu Z,Zhang W,Lu Y,Lu C

Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology.
PLoS genetics4(7)e1000121(2008 Jul)
Lam SH,Mathavan S,Tong Y,Li H,Karuturi RK,Wu Y,Vega VB,Liu ET,Gong Z