ccdc80 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	ccdc80
Entrez Gene ID	368419
Full Name	coiled-coil domain containing 80
Synonyms	CL2,SSG-1,si:bz20i5.2,ssg1,zgc:113236
General protein information	Preferred Names coiled-coil domain containing 80 Names coiled-coil domain-containing protein 80 steroid sensitive gene 1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001007198.1	NP_001007199.1	coiled-coil domain-containing protein 80 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	CCDC80	NP_955805.1
Mus musculus (house mouse)	Ccdc80	NP_080715.2
Danio rerio (zebrafish)	ccdc80	NP_001007199.1
Canis lupus familiaris (dog)	CCDC80	XP_005639700.1
Rattus norvegicus (Norway rat)	Ccdc80	NP_071988.2
Pan troglodytes (chimpanzee)	CCDC80	XP_001156251.2
	CCDC80	XP_002802691.1
Bos taurus (cattle)	CCDC80	NP_001092452.1
Gallus gallus (chicken)	CCDC80	NP_989762.1

Gene Ontology
Bibliography

Related articles in PubMed

Comparative Transcriptome Analysis Identifies CCDC80 as a Novel Gene Associated with Pulmonary Arterial Hypertension.
Sasagawa S, Nishimura Y, Sawada H, Zhang E, Okabe S, Murakami S, Ashikawa Y, Yuge M, Kawaguchi K, Kawase R, Mitani Y, Maruyama K, Tanaka T
Frontiers in pharmacology7142(2016)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

scaRNAs regulate splicing and vertebrate heart development.
Patil P, Kibiryeva N, Uechi T, Marshall J, O'Brien JE Jr, Artman M, Kenmochi N, Bittel DC
Biochimica et biophysica acta1852(8)1619-29(2015 Aug)

The Coiled-Coil Domain Containing 80 (ccdc80) gene regulates gadd45?2 expression in the developing somites of zebrafish as a new player of the hedgehog pathway.
Della Noce I, Carra S, Brusegan C, Critelli R, Frassine A, De Lorenzo C, Giordano A, Bellipanni G, Villa E, Cotelli F, Pistocchi A, Schepis F
Journal of cellular physiology230(4)821-30(2015 Apr)

Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish.
Musso G, Tasan M, Mosimann C, Beaver JE, Plovie E, Carr LA, Chua HN, Dunham J, Zuberi K, Rodriguez H, Morris Q, Zon L, Roth FP, MacRae CA
Development (Cambridge, England)141(1)224-35(2014 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

investigated the functional effects of Coiled-Coil Domain Containing 80-loss-of-function during embryonic development and verified its interaction with gadd45beta2 in somitogenesis
Title: The Coiled-Coil Domain Containing 80 (ccdc80) gene regulates gadd45?2 expression in the developing somites of zebrafish as a new player of the hedgehog pathway.

analysis of zebrafish Ccdc80 and Ccdc80-like1 (Ccdc80-l1) proteins; Ccdc80-l1 is involved in axon pathfinding of zebrafish motoneurons
Title: Ccdc80-l1 Is involved in axon pathfinding of zebrafish motoneurons.

The following ccdc80 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ccdc80 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa00876	NM_001007198.1 Latest version!	Danio rerio coiled-coil domain containing 80 (ccdc80), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$510.30 $729.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ccdc80 ( NM_001007198.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001007199.1 Danio rerio coiled-coil domain containing 80 (ccdc80), mRNA.

Price & Availability↑

CloneID	ODa00876
Clone ID Related Accession (Same CDS sequence)	NM_001007198.1
Accession Version	NM_001007198.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2604bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Danio rerio(zebrafish)
Product	coiled-coil domain-containing protein 80 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL590146.2. ##Evidence-Data-START## Transcript exon combination :: BC171523.1, EU269066.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGAGGGCAC GGTATATGCT TGGTTTCGGT GTTTTGTGTC TGTTGACATG GGCTGTTTAC 
GTGTCAGAAA GCAGCCCGAC CGATAAACAG GCTAAACTCA GACTGATGTC CGTACGACGA 
GCAAGACAAA ACAAATCCCG ACAGGGTCAG ATCATTAAAA CACGTGCTTC TTCTACATGG 
ATCAATGATA AACGCCAACA GATGCAGGGA GACGAAGGTG TACAATTTAG AAGGAATGTC 
CAATCCAGAA AGGTCTTGGC ACAAAGGAGA CCAGCACAGG GTGGGACAAG GAATCCAATC 
CAGCAAGATG ATGGAACACC TGGAGCCAGG GCCAGAGTGT CCCGCATGCC AAGCAGTGCT 
GGTTCTCCAA ACCTACTGGC GTCATTTGCA GGGAAAAACC GCCTACTGGT TATTTCCGCA 
CCTCACGACT CTGATGGCTA CTACAGATTG ATGATGAGTC TGCTTAAACC TGAGGTTTAC 
TGTGAGTTGG CTGAGCGGCA CGTGCACCAG ATTGTCATGT TCCATCAGGA AGGAGAGTTG 
GGTGGGAAAA TCAGACGCAT TACTAATGAA GGGAAAGTGA TGGAAGAGCC ATTAGATACT 
GCTCTCATTC CCAGGCTCAT GACCTTTCTA AAATTAGAGA AAGGAAAGTT TGGGATGGTT 
CTTCTTAAGA AGACGCTTCA GGTGGAGGAA CGGTATCCAT ACCCGGTCCG ACTGGAAGCA 
ATGTATGAAG TTATCGACCA GTCACCTATG CGCAAAATGG AAAAAGTACG GCAGAAAGGC 
TTTGTGCAGA AGTGTAAAGG GGCTGGGGTG GAGGGTCAGG TGGTTGAGGG TGTCCTGACC 
ACTGATTCCC AGGTGGACCC ACCAACAGAA AGGAGAAAAG AGATTCGGAA ACCCATTCGA 
AGACCAACAA CAACTACCAC TCCAGCTCCA ACAAGACCAA CAACTACCAC CACCACTACC 
AAAGCAACTA CTACCACCAC AACACGTCCC CCAACTACAA CCCGATCTAC CACCACCACA 
ACAACAACGA CAACAACAAC AACGCGGCCA ACCACAACAA CAACACGGAC CACCACCACT 
CCAAGGACTA CCAGAGCTAA TACTACCCCT CAATGGATCC CAGCCCACAA GACCACTGCC 
GAACCTTACT ATTACAATCG TAGGGACAGA TACCAGACCA CCTCACCCCC AACTGACTCA 
GCAAGATACA GAGACAACCA CACTTCTAAA AAAGAATACA ACCATAGACA TACCAACACT 
ATACCAACAC AACACAAGCC AACTAAAGTA AGGCCTACAA AGAAAAAGAA TGGCGATAAA 
GATATTAGCA ACGCGTATGA GGAGAAATAT GACGTAGGTG TGCCTACCGA TGCCTATCCT 
GAAGAAAAAG AGGAAGAAAT CGTGCCCACC AAAAGAGGCA AGGGCAAAAC AGATAAAAAG 
AAGAAAAAGG ACAAGACAGA TAAGCTGTCT AAAAAGGACA AAGCAGAGAG GAGAGGAAAA 
GATGGAAAGG GTGGTAAGAA AAATGGAAAG AAAGTTCCAA AGATTCTTGA GAAAGAAGAT 
TATCAGAAAC CAACAAAAAG ACCACCACCG CCACCGCCAC CTAAAGGAAC TCTGGCAACC 
TTTTTGGACT ATTTTGAAAG CAGGAGGAGA TTAATTTTGA TCACCTCTCC AACAGAGGAG 
AACAGCATGT ATATTCAGCA GAGGGATGAA TACTTGGAGC ACGTGTGTGA AATGGCAATC 
AGGAAAGTAA CCATCATCAC CATCTTTGGC ACATTTAGGA ATAGCACCAT GAAAATTGAT 
CATTACCAGC TTGAGAAGGA CAAGCCCATG AAAGGTCTGA GACAGGAGGA TTTGGAGAAC 
CAGGATCTCA TCATGGAGCT GAGGAAAGAG TACGGAATGA CCTACAACGA TTTCTACGTG 
GTCCTCACAG ATCTGGACAT GAAGGCGAAG CAATACTATG AAGTGCCAAT TGCAATGAAG 
GCTGTGTTCG ACTACATCGA CACGTTTTCA TCACGTATCA GAGAGATGGA GCAACAGAAG 
AGGGATGGGG TGACGTGCAA AAAAGAAGAC AAGCCCAGAT CATTGGAGAA CTTCCTTTCC 
AGATTCCGCT GGAGACGCAG GTTGTTTGTC ATATCTGCAC CAAACGATGA GGAATGGGCC 
TATCAGCAAC AGCTTTATGC ACTGACCAGT CAGGCCTGCA ACCTGGGTCT TCGTCATGTG 
TCCGTGCTGA AGCTGGTCGG TACAGACCTG TTAGACATGG GAGGAGTGTT AGAGCTTTAC 
CCCATCAACG GTAGTGCAAC GGTGGAGCGT GAGGGTATCT CTGCCACTCT AGTAAGAGAC 
ATCAGAAACT ACTTCCAGAT CAGCCCCGAG TACTTTTCCA TGCTGCTGGT TGGAAAAGAC 
GGAAATGTCA AATCCTGGTA CCCGTCACCC ATGTGGTCCA TGGCCATCAT CTATGACCTG 
ATCGACTCCA TGCAGCTCCG CAGACAGGAA ATGGCCATCC AGCAGTCTCT AGGTATGCGC 
TGCCCTGAGG ATGAGTACGG TGGATATGGT TATCATCATC ATGAGGGTTA CCAGGAAGGT 
TATCATCAGG GTTATGGATA TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007199.1
CDS	1..2604
Translation	MRARYMLGFGVLCLLTWAVYVSESSPTDKQAKLRLMSVRRARQNKSRQGQIIKTRASSTWINDKRQQMQGDEGVQFRRNVQSRKVLAQRRPAQGGTRNPIQQDDGTPGARARVSRMPSSAGSPNLLASFAGKNRLLVISAPHDSDGYYRLMMSLLKPEVYCELAERHVHQIVMFHQEGELGGKIRRITNEGKVMEEPLDTALIPRLMTFLKLEKGKFGMVLLKKTLQVEERYPYPVRLEAMYEVIDQSPMRKMEKVRQKGFVQKCKGAGVEGQVVEGVLTTDSQVDPPTERRKEIRKPIRRPTTTTTPAPTRPTTTTTTTKATTTTTTRPPTTTRSTTTTTTTTTTTTRPTTTTTRTTTTPRTTRANTTPQWIPAHKTTAEPYYYNRRDRYQTTSPPTDSARYRDNHTSKKEYNHRHTNTIPTQHKPTKVRPTKKKNGDKDISNAYEEKYDVGVPTDAYPEEKEEEIVPTKRGKGKTDKKKKKDKTDKLSKKDKAERRGKDGKGGKKNGKKVPKILEKEDYQKPTKRPPPPPPPKGTLATFLDYFESRRRLILITSPTEENSMYIQQRDEYLEHVCEMAIRKVTIITIFGTFRNSTMKIDHYQLEKDKPMKGLRQEDLENQDLIMELRKEYGMTYNDFYVVLTDLDMKAKQYYEVPIAMKAVFDYIDTFSSRIREMEQQKRDGVTCKKEDKPRSLENFLSRFRWRRRLFVISAPNDEEWAYQQQLYALTSQACNLGLRHVSVLKLVGTDLLDMGGVLELYPINGSATVEREGISATLVRDIRNYFQISPEYFSMLLVGKDGNVKSWYPSPMWSMAIIYDLIDSMQLRRQEMAIQQSLGMRCPEDEYGGYGYHHHEGYQEGYHQGYGY

Target ORF information:

RefSeq Version	NM_001007198.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio coiled-coil domain containing 80 (ccdc80), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007198.1

ORF Insert Sequence:

ATGAGGGCAC GGTATATGCT TGGTTTCGGT GTTTTGTGTC TGTTGACATG GGCTGTTTAC 
GTGTCAGAAA GCAGCCCGAC CGATAAACAG GCTAAACTCA GACTGATGTC CGTACGACGA 
GCAAGACAAA ACAAATCCCG ACAGGGTCAG ATCATTAAAA CACGTGCTTC TTCTACATGG 
ATCAATGATA AACGCCAACA GATGCAGGGA GACGAAGGTG TACAATTTAG AAGGAATGTC 
CAATCCAGAA AGGTCTTGGC ACAAAGGAGA CCAGCACAGG GTGGGACAAG GAATCCAATC 
CAGCAAGATG ATGGAACACC TGGAGCCAGG GCCAGAGTGT CCCGCATGCC AAGCAGTGCT 
GGTTCTCCAA ACCTACTGGC GTCATTTGCA GGGAAAAACC GCCTACTGGT TATTTCCGCA 
CCTCACGACT CTGATGGCTA CTACAGATTG ATGATGAGTC TGCTTAAACC TGAGGTTTAC 
TGTGAGTTGG CTGAGCGGCA CGTGCACCAG ATTGTCATGT TCCATCAGGA AGGAGAGTTG 
GGTGGGAAAA TCAGACGCAT TACTAATGAA GGGAAAGTGA TGGAAGAGCC ATTAGATACT 
GCTCTCATTC CCAGGCTCAT GACCTTTCTA AAATTAGAGA AAGGAAAGTT TGGGATGGTT 
CTTCTTAAGA AGACGCTTCA GGTGGAGGAA CGGTATCCAT ACCCGGTCCG ACTGGAAGCA 
ATGTATGAAG TTATCGACCA GTCACCTATG CGCAAAATGG AAAAAGTACG GCAGAAAGGC 
TTTGTGCAGA AGTGTAAAGG GGCTGGGGTG GAGGGTCAGG TGGTTGAGGG TGTCCTGACC 
ACTGATTCCC AGGTGGACCC ACCAACAGAA AGGAGAAAAG AGATTCGGAA ACCCATTCGA 
AGACCAACAA CAACTACCAC TCCAGCTCCA ACAAGACCAA CAACTACCAC CACCACTACC 
AAAGCAACTA CTACCACCAC AACACGTCCC CCAACTACAA CCCGATCTAC CACCACCACA 
ACAACAACGA CAACAACAAC AACGCGGCCA ACCACAACAA CAACACGGAC CACCACCACT 
CCAAGGACTA CCAGAGCTAA TACTACCCCT CAATGGATCC CAGCCCACAA GACCACTGCC 
GAACCTTACT ATTACAATCG TAGGGACAGA TACCAGACCA CCTCACCCCC AACTGACTCA 
GCAAGATACA GAGACAACCA CACTTCTAAA AAAGAATACA ACCATAGACA TACCAACACT 
ATACCAACAC AACACAAGCC AACTAAAGTA AGGCCTACAA AGAAAAAGAA TGGCGATAAA 
GATATTAGCA ACGCGTATGA GGAGAAATAT GACGTAGGTG TGCCTACCGA TGCCTATCCT 
GAAGAAAAAG AGGAAGAAAT CGTGCCCACC AAAAGAGGCA AGGGCAAAAC AGATAAAAAG 
AAGAAAAAGG ACAAGACAGA TAAGCTGTCT AAAAAGGACA AAGCAGAGAG GAGAGGAAAA 
GATGGAAAGG GTGGTAAGAA AAATGGAAAG AAAGTTCCAA AGATTCTTGA GAAAGAAGAT 
TATCAGAAAC CAACAAAAAG ACCACCACCG CCACCGCCAC CTAAAGGAAC TCTGGCAACC 
TTTTTGGACT ATTTTGAAAG CAGGAGGAGA TTAATTTTGA TCACCTCTCC AACAGAGGAG 
AACAGCATGT ATATTCAGCA GAGGGATGAA TACTTGGAGC ACGTGTGTGA AATGGCAATC 
AGGAAAGTAA CCATCATCAC CATCTTTGGC ACATTTAGGA ATAGCACCAT GAAAATTGAT 
CATTACCAGC TTGAGAAGGA CAAGCCCATG AAAGGTCTGA GACAGGAGGA TTTGGAGAAC 
CAGGATCTCA TCATGGAGCT GAGGAAAGAG TACGGAATGA CCTACAACGA TTTCTACGTG 
GTCCTCACAG ATCTGGACAT GAAGGCGAAG CAATACTATG AAGTGCCAAT TGCAATGAAG 
GCTGTGTTCG ACTACATCGA CACGTTTTCA TCACGTATCA GAGAGATGGA GCAACAGAAG 
AGGGATGGGG TGACGTGCAA AAAAGAAGAC AAGCCCAGAT CATTGGAGAA CTTCCTTTCC 
AGATTCCGCT GGAGACGCAG GTTGTTTGTC ATATCTGCAC CAAACGATGA GGAATGGGCC 
TATCAGCAAC AGCTTTATGC ACTGACCAGT CAGGCCTGCA ACCTGGGTCT TCGTCATGTG 
TCCGTGCTGA AGCTGGTCGG TACAGACCTG TTAGACATGG GAGGAGTGTT AGAGCTTTAC 
CCCATCAACG GTAGTGCAAC GGTGGAGCGT GAGGGTATCT CTGCCACTCT AGTAAGAGAC 
ATCAGAAACT ACTTCCAGAT CAGCCCCGAG TACTTTTCCA TGCTGCTGGT TGGAAAAGAC 
GGAAATGTCA AATCCTGGTA CCCGTCACCC ATGTGGTCCA TGGCCATCAT CTATGACCTG 
ATCGACTCCA TGCAGCTCCG CAGACAGGAA ATGGCCATCC AGCAGTCTCT AGGTATGCGC 
TGCCCTGAGG ATGAGTACGG TGGATATGGT TATCATCATC ATGAGGGTTA CCAGGAAGGT 
TATCATCAGG GTTATGGATA TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Comparative Transcriptome Analysis Identifies CCDC80 as a Novel Gene Associated with Pulmonary Arterial Hypertension.
Frontiers in pharmacology7142(2016)
Sasagawa S,Nishimura Y,Sawada H,Zhang E,Okabe S,Murakami S,Ashikawa Y,Yuge M,Kawaguchi K,Kawase R,Mitani Y,Maruyama K,Tanaka T

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

scaRNAs regulate splicing and vertebrate heart development.
Biochimica et biophysica acta1852(8)1619-29(2015 Aug)
Patil P,Kibiryeva N,Uechi T,Marshall J,O'Brien JE Jr,Artman M,Kenmochi N,Bittel DC

The Coiled-Coil Domain Containing 80 (ccdc80) gene regulates gadd45?2 expression in the developing somites of zebrafish as a new player of the hedgehog pathway.
Journal of cellular physiology230(4)821-30(2015 Apr)
Della Noce I,Carra S,Brusegan C,Critelli R,Frassine A,De Lorenzo C,Giordano A,Bellipanni G,Villa E,Cotelli F,Pistocchi A,Schepis F

Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish.
Development (Cambridge, England)141(1)224-35(2014 Jan)
Musso G,Tasan M,Mosimann C,Beaver JE,Plovie E,Carr LA,Chua HN,Dunham J,Zuberi K,Rodriguez H,Morris Q,Zon L,Roth FP,MacRae CA

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ccdc80 cDNA ORF clone, Danio rerio(zebrafish)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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