hbae1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	hbae1
Entrez Gene ID	30597
Full Name	hemoglobin, alpha embryonic 1
Synonyms	HBA2r,HBAA1,SI:dZ118J2.10,SI:dZ118J2.8,dZ118J2.6,hba2,si:by119c3.1,si:by119c3.3,si:xx-119c3.3,wu:fa12a11,wu:fb74f06,zgc:86936
General protein information	Preferred Names hemoglobin, alpha embryonic 1 Names hemoglobin, alpha embryonic 1 HbA alphae1globin etID40432.3 globin alphae1 hemoglobin alpha-2 chain
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_182940.3	NP_891985.1	hemoglobin, alpha embryonic 1.1
NM_182940.2	NP_891985.1	hemoglobin, alpha embryonic 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	HBZ	NP_005323.1
Canis lupus familiaris (dog)	LOC100855634	XP_003639178.1
Xenopus tropicalis (tropical clawed frog)	hba4	NP_001135556.1
Xenopus tropicalis (tropical clawed frog)	hbz	NP_001005092.1
Xenopus tropicalis (tropical clawed frog)	hba-l5	NP_001016009.1
Xenopus tropicalis (tropical clawed frog)	hba2	NP_001135724.1
Gallus gallus (chicken)	LOC100858080	XP_003643241.1
Danio rerio (zebrafish)	si:xx-by187g17.1	NP_001028265.1
Danio rerio (zebrafish)	LOC100334599	XP_002661306.1
Danio rerio (zebrafish)	si:ch211-5k11.2	XP_001333555.1
Xenopus tropicalis (tropical clawed frog)	hba-l2	NP_001107321.1
Xenopus tropicalis (tropical clawed frog)	hba3	NP_001015904.1
Gallus gallus (chicken)	HBZ	NP_001004374.1
Pan troglodytes (chimpanzee)	HBZ	XP_001151351.1
Rattus norvegicus (Norway rat)	Hbz	NP_001166316.1
Danio rerio (zebrafish)	si:ch211-5k11.6	XP_005164395.1
Danio rerio (zebrafish)	hbae1	NP_891985.1
Xenopus tropicalis (tropical clawed frog)	hba-l4	NP_001165374.1
Xenopus tropicalis (tropical clawed frog)	hba-l3	NP_001165373.1
Canis lupus familiaris (dog)	LOC100855600	XP_003639176.1
Mus musculus (house mouse)	Hba-x	NP_034535.1
Danio rerio (zebrafish)	hbaa1	NP_571332.2
Danio rerio (zebrafish)	hbz	XP_685362.2

Gene Ontology
Bibliography

Related articles in PubMed

Computational and functional analysis of biopharmaceutical drugs in zebrafish: Erythropoietin as a test model.
Guarienti M, Giacopuzzi E, Gianoncelli A, Sigala S, Spano P, Pecorelli S, Pani L, Memo M
Pharmacological research10212-21(2015 Dec)

Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction.
Jia XE, Ma K, Xu T, Gao L, Wu S, Fu C, Zhang W, Wang Z, Liu K, Dong M, Jing C, Ren C, Dong Z, Chen Y, Jin Y, Huang Q, Chang X, Deng M, Li L, Luo L, Zhu J, Dang Y, Chang HC, Zon LI, Zhou Y, Chen S, Pan W
Cell research25(8)946-62(2015 Aug)

Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress.
Rissone A, Weinacht KG, la Marca G, Bishop K, Giocaliere E, Jagadeesh J, Felgentreff K, Dobbs K, Al-Herz W, Jones M, Chandrasekharappa S, Kirby M, Wincovitch S, Simon KL, Itan Y, DeVine A, Schlaeger T, Schambach A, Sood R, Notarangelo LD, Candotti F
The Journal of experimental medicine212(8)1185-202(2015 Jul)

TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis.
Gao L, Li D, Ma K, Zhang W, Xu T, Fu C, Jing C, Jia X, Wu S, Sun X, Dong M, Deng M, Chen Y, Zhu W, Peng J, Wan F, Zhou Y, Zon LI, Pan W
PLoS genetics11(7)e1005346(2015 Jul)

Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish.
Seiler C, Gebhart N, Zhang Y, Shinton SA, Li YS, Ross NL, Liu X, Li Q, Bilbee AN, Varshney GK, LaFave MC, Burgess SM, Balciuniene J, Balciunas D, Hardy RR, Kappes DJ, Wiest DL, Rhodes J
PloS one10(7)e0131908(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that during embryonic development, depletion of Grx3 severely impairs the maturation of hemoglobin, the major iron-consuming process.
Title: Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation.

The following hbae1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the hbae1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa00891	NM_182940.2 Latest version!	Danio rerio hemoglobin, alpha embryonic 1 (hbae1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
ODa159703	NM_182940.3 Latest version!	Danio rerio hemoglobin, alpha embryonic 1.1 (hbae1.1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

hbae1 ( NM_182940.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_891985.1 Danio rerio hemoglobin, alpha embryonic 1 (hbae1), mRNA.

Price & Availability↑

CloneID	ODa00891
Clone ID Related Accession (Same CDS sequence)	NM_182940.2
Accession Version	NM_182940.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 432bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-07-02
Organism	Danio rerio(zebrafish)
Product	hemoglobin, alpha embryonic 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC071550.1. On Oct 3, 2004 this sequence version replaced NM_182940.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC071550.1, FP214026.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END##

ATGAGTCTCT CTGCCAAAGA CAAAGCTGCC GTCAAAACCC TGTGGGCCAA GATCGCTGGA 
AAGGCTGACG ACATCGGTCA CGATGCTCTC TCCAGGATGT TGATTGTCTA CCCCCAGACC 
AAGACCTACT TCTCTCACTG GAAAGACCTG AGCCCAGGCT CTGCCCCAGT GAGGAAACAC 
GGCAAGACTG TGATGGGTGG CGTTGCTGAG GCTGTCAGCA AAATCGATGA CCTTAATGCC 
GGACTCCTGA ACCTCAGTGA GCTCCATGCT TTCCAGCTGC GTGTGGACCC CGCCAATTTC 
AAGATTCTGT CCCACAACAT CCTCGTGGTT CTGGCCACTT TGTTCCCCGC CGACTTCACT 
CCTGAAGCTC ATGTTGCAAT GGACAAGTTC CTCTCAGCTC TGGCTCTGGC CATGTCTGAG 
AAGTACAGAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_891985.1
CDS	33..464
Translation	MSLSAKDKAAVKTLWAKIAGKADDIGHDALSRMLIVYPQTKTYFSHWKDLSPGSAPVRKHGKTVMGGVAEAVSKIDDLNAGLLNLSELHAFQLRVDPANFKILSHNILVVLATLFPADFTPEAHVAMDKFLSALALAMSEKYR

Target ORF information:

RefSeq Version	NM_182940.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio hemoglobin, alpha embryonic 1 (hbae1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182940.2

ORF Insert Sequence:

ATGAGTCTCT CTGCCAAAGA CAAAGCTGCC GTCAAAACCC TGTGGGCCAA GATCGCTGGA 
AAGGCTGACG ACATCGGTCA CGATGCTCTC TCCAGGATGT TGATTGTCTA CCCCCAGACC 
AAGACCTACT TCTCTCACTG GAAAGACCTG AGCCCAGGCT CTGCCCCAGT GAGGAAACAC 
GGCAAGACTG TGATGGGTGG CGTTGCTGAG GCTGTCAGCA AAATCGATGA CCTTAATGCC 
GGACTCCTGA ACCTCAGTGA GCTCCATGCT TTCCAGCTGC GTGTGGACCC CGCCAATTTC 
AAGATTCTGT CCCACAACAT CCTCGTGGTT CTGGCCACTT TGTTCCCCGC CGACTTCACT 
CCTGAAGCTC ATGTTGCAAT GGACAAGTTC CTCTCAGCTC TGGCTCTGGC CATGTCTGAG 
AAGTACAGAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

hbae1 ( NM_182940.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_891985.1 Danio rerio hemoglobin, alpha embryonic 1.1 (hbae1.1), mRNA.

Price & Availability↑

CloneID	ODa159703
Clone ID Related Accession (Same CDS sequence)	NM_182940.3
Accession Version	NM_182940.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 432bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-20
Organism	Danio rerio(zebrafish)
Product	hemoglobin, alpha embryonic 1.1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL935210.8. On Aug 18, 2018 this sequence version replaced NM_182940.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC071550.1, EB869891.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END##

ATGAGTCTCT CTGCCAAAGA CAAAGCTGCC GTCAAAACCC TGTGGGCCAA GATCGCTGGA 
AAGGCTGACG ACATCGGACA CGATGCTCTC TCCAGGATGT TGATTGTCTA CCCCCAGACC 
AAGACCTACT TCTCTCACTG GAAAGACCTG AGCCCAGGCT CTGCCCCAGT GAGGAAACAC 
GGCAAGACTG TGATGGGAGG CGTTGCTGAG GCTGTCAGCA AAATCGATGA CCTTAATGCC 
GGACTCCTGA ACCTCAGTGA GCTCCATGCT TTCCAGCTGC GTGTGGACCC CGCCAATTTC 
AAGATTCTGT CCCACAACAT CCTCGTGGTT CTGGCCACTT TGTTCCCCGC CGATTTCACT 
CCTGAGGCTC ATGTTGCAAT GGACAAGTTC CTCTCAGCTC TGGCTCTGGC CATGTCTGAG 
AAGTACAGAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_891985.1
CDS	33..464
Translation	MSLSAKDKAAVKTLWAKIAGKADDIGHDALSRMLIVYPQTKTYFSHWKDLSPGSAPVRKHGKTVMGGVAEAVSKIDDLNAGLLNLSELHAFQLRVDPANFKILSHNILVVLATLFPADFTPEAHVAMDKFLSALALAMSEKYR

Target ORF information:

RefSeq Version	NM_182940.3
Organism	Danio rerio(zebrafish)
Definition	Danio rerio hemoglobin, alpha embryonic 1.1 (hbae1.1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182940.3

ORF Insert Sequence:

ATGAGTCTCT CTGCCAAAGA CAAAGCTGCC GTCAAAACCC TGTGGGCCAA GATCGCTGGA 
AAGGCTGACG ACATCGGACA CGATGCTCTC TCCAGGATGT TGATTGTCTA CCCCCAGACC 
AAGACCTACT TCTCTCACTG GAAAGACCTG AGCCCAGGCT CTGCCCCAGT GAGGAAACAC 
GGCAAGACTG TGATGGGAGG CGTTGCTGAG GCTGTCAGCA AAATCGATGA CCTTAATGCC 
GGACTCCTGA ACCTCAGTGA GCTCCATGCT TTCCAGCTGC GTGTGGACCC CGCCAATTTC 
AAGATTCTGT CCCACAACAT CCTCGTGGTT CTGGCCACTT TGTTCCCCGC CGATTTCACT 
CCTGAGGCTC ATGTTGCAAT GGACAAGTTC CTCTCAGCTC TGGCTCTGGC CATGTCTGAG 
AAGTACAGAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Computational and functional analysis of biopharmaceutical drugs in zebrafish: Erythropoietin as a test model.
Pharmacological research10212-21(2015 Dec)
Guarienti M,Giacopuzzi E,Gianoncelli A,Sigala S,Spano P,Pecorelli S,Pani L,Memo M

Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction.
Cell research25(8)946-62(2015 Aug)
Jia XE,Ma K,Xu T,Gao L,Wu S,Fu C,Zhang W,Wang Z,Liu K,Dong M,Jing C,Ren C,Dong Z,Chen Y,Jin Y,Huang Q,Chang X,Deng M,Li L,Luo L,Zhu J,Dang Y,Chang HC,Zon LI,Zhou Y,Chen S,Pan W

Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress.
The Journal of experimental medicine212(8)1185-202(2015 Jul)
Rissone A,Weinacht KG,la Marca G,Bishop K,Giocaliere E,Jagadeesh J,Felgentreff K,Dobbs K,Al-Herz W,Jones M,Chandrasekharappa S,Kirby M,Wincovitch S,Simon KL,Itan Y,DeVine A,Schlaeger T,Schambach A,Sood R,Notarangelo LD,Candotti F

TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis.
PLoS genetics11(7)e1005346(2015 Jul)
Gao L,Li D,Ma K,Zhang W,Xu T,Fu C,Jing C,Jia X,Wu S,Sun X,Dong M,Deng M,Chen Y,Zhu W,Peng J,Wan F,Zhou Y,Zon LI,Pan W

Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish.
PloS one10(7)e0131908(2015)
Seiler C,Gebhart N,Zhang Y,Shinton SA,Li YS,Ross NL,Liu X,Li Q,Bilbee AN,Varshney GK,LaFave MC,Burgess SM,Balciuniene J,Balciunas D,Hardy RR,Kappes DJ,Wiest DL,Rhodes J

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

hbae1 cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報