ntrk1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	ntrk1
Entrez Gene ID	30546
Full Name	neurotrophic tyrosine kinase, receptor, type 1
Synonyms	trk,trka
General protein information	Preferred Names neurotrophic tyrosine kinase, receptor, type 1 Names high affinity nerve growth factor receptor tyrosine kinase receptor A
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001301356.1	NP_001288285.1	high affinity nerve growth factor receptor precursor

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	ntrk1	XP_002939035.1
Pan troglodytes (chimpanzee)	NTRK1	XP_003308563.1
	NTRK1	XP_001114243.2
Mus musculus (house mouse)	Ntrk1	NP_001028296.1
Canis lupus familiaris (dog)	NTRK1	XP_851619.3
Rattus norvegicus (Norway rat)	Ntrk1	NP_067600.1
Homo sapiens (human)	NTRK1	NP_002520.2
Bos taurus (cattle)	NTRK1	XP_002686012.2
Gallus gallus (chicken)	NTRK1	NP_990709.1
Danio rerio (zebrafish)	ntrk1	XP_697246.5

Gene Ontology
Bibliography

Related articles in PubMed

A comprehensive analysis of neurotrophins and neurotrophin tyrosine kinase receptors expression during development of zebrafish.
Nittoli V, Sepe RM, Coppola U, D'Agostino Y, De Felice E, Palladino A, Vassalli QA, Locascio A, Ristoratore F, Spagnuolo A, D'Aniello S, Sordino P
The Journal of comparative neurology(2018 Jan)

Crypt cell markers in the olfactory organ of Poecilia reticulata: analysis and comparison with the fish model Danio rerio.
Bettini S, Milani L, Lazzari M, Maurizii MG, Franceschini V
Brain structure & function222(7)3063-3074(2017 Sep)

An ancient neurotrophin receptor code; a single Runx/Cbf? complex determines somatosensory neuron fate specification in zebrafish.
Gau P, Curtright A, Condon L, Raible DW, Dhaka A
PLoS genetics13(7)e1006884(2017 Jul)

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

By immunohistochemistry, the localization of Neurotrophinss has been observed mainly in Purkinje cells; TrkA and TrkB-receptors in cells and fibers of granular and molecular layers. TrkC was faintly detected
Title: Neurotrophins and their Trk-receptors in the cerebellum of zebrafish.

Present results demonstrate that as for mammals neurotrophins might play a role in sensory cells of the teleostean taste buds.
Title: Neurotrophin receptors in taste buds of adult zebrafish (Danio rerio).

TrkA-like immunoreactivity was the only Trk detected, and it was restricted to the somata of crypt sensory neurons, their central processes being apparently unreactive.
Title: The crypt neurons in the olfactory epithelium of the adult zebrafish express TrkA-like immunoreactivity.

The following ntrk1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ntrk1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa21930	NM_001301356.1 Latest version!	Danio rerio neurotrophic tyrosine kinase, receptor, type 1 (ntrk1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ntrk1 ( NM_001301356.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001288285.1 Danio rerio neurotrophic tyrosine kinase, receptor, type 1 (ntrk1), mRNA.

Price & Availability↑

CloneID	ODa21930
Clone ID Related Accession (Same CDS sequence)	NM_001301356.1
Accession Version	NM_001301356.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2394bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Danio rerio(zebrafish)
Product	high affinity nerve growth factor receptor precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR933818.11. On Aug 12, 2014 this sequence version replaced XM_692154.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2168447, SAMEA3505370 [ECO:0000350] ##Evidence-Data-END##

ATGGCTGACC ATAGGGTGGC CCCGGTTGTG GGTTTTCTCC TTTTTTTGGT TGCACCGGTC 
TGGAGCGGAT GCCCAAGCGC ATGCCGCTGC TCCTTCGCTA TGCTACAATG CCTGGAGTCA 
GATGGCATCA CCAGCATCCC GGCGCTGGCA GCGCAGGAGA GTGAAAACGT CACTGAAATC 
TACATAGAGA GTCAACCCAA CCTGGAGAAC ATCACAGATG TAGACCTCGC CAACTACAGA 
GAACTGAAGA ATCTGACGAT CACAGATTGT GGGTTGGTGT ACATCTCTGA AAATGCCTTT 
CAGCATAACT TCAAGCTGCA GTATGTAAAC CTGGCCTCTA ATGCACTGAC GCACATCAGT 
TGGAGGGTGT TCCAATCTGT GACTCTATTG AGTCTGATTT TGAGGGACAA TCTGCTCACC 
TGCTCGTGTG ACATTTACTG GCTTCAGCAG TGGCACAGAA AAAGACTAAA CGAAATTGAT 
TCTCAGCAAA ATTGCATTTA CAATGGCAGC CAGATTCCGC TGGATTCATT CGAAATGGAT 
AACTGCAGTG TTCCTGAGGT CATGATTGAC CCACCGACAG TGACCACTCA AGAAGGTGGA 
AATTTGACAT TTACCTGCAG AGTGACTGGA GTTCCCACAC CGACGATCCA CTGGAGAACT 
GAGCAGCTTC GGTCCAGCTG GACCCTGGAG CAAGGAATCT GGGGATCAAC CCTGGAGGTG 
GTTCTGCACA TGAGAAATGT GTCTTCTGCT GACAACCTGC ACAACCTCAC CTGTGAAGCG 
GAGAATCGCG CTGGAATGGG AGATGCTGTG GTGCAGCTGG ACATTGAATT TCCAGTGCGG 
ATCATATATC TCAAGAACCC AGAATCTCAA CATCACTGGT GTTTCCCGTT CGCCGTAGAC 
AGCAATCCTC CCGCCAGCAT CAAATGGCTG TACAACAACA TGCCTCTCAC TGAGACCCGC 
TATGCCTACA CTGAACTCAT CAGAGACGTG TACGACGGCT CACAGCAACA CGGCTGTCTG 
TTCCTTAACA AACCCACTCA TCTCAACAAC GGCAACTACA CAATCATCGT GAAGAACAAA 
CTGGGCAGAG ACCAGAGAAC AGTCCGAGCC AAGTTCATGG ACAATCCTTT TGATCCCTCT 
GACCCGGAGG GCATCATCCC TGTGCTCAAT GACGACCCAA CAGCTCCCAC TAACCAATCA 
ACGGAGACGG AGAAAATAGA GAGCAGAGTG TTTGGGGTGT CAGTAGCTGT GGGCCTCGCT 
GTGTTTGCGT GCACATTTCT GCTCATCATG GTTGTTGTCA TTAATAAATG TGGACAGCAC 
TCCAAGTTTG GCATCCACCG TTCATCAGTT CTGGGCACCG AGGATGATCT GGCAGTGTCT 
CTCCGCTTCA TGAACTTCGG TGCTAGTCCT CCATCTTCAG ATGACGGCAC ACTGGATTCT 
GGCTTGTCCA GTTTTGTGGA GAACCCGCAA TATTTCTGTG GCATTATCAA AGATAAAGAC 
ATGTGTGTTC AGCACATTAA AAGAAAAGAC ATTGTTTTGA AGTGGGAACT GGGTGAAGGA 
GCTTTTGGCA AGGTTTATCT GGCTGAATGT GCCAATCTCT GTCCTGATAC TGACAAGATG 
CTGGTTGCTA TCAAGACTTT GAAAATAGCC AATGAGTCCA CCCGGCAGGA CTTCCAGCGC 
GAGGCTGAGC TGCTCACGGT GCTTCAGCAC GAACACATTG TGCGCTTCTA CGGTGTGTGC 
GCAGACGGAG AACCCCTGGC CATGGTGTTT GAGTACATGC GACACGGAGA CCTCAACCGC 
TTTCTAAGGG CTCACGGTCC CGATGCTCGT ATATTAGATG AGATGAAGGT TCCTCCGATG 
GGTCAGTTGA CTCTTCCTCA GATGCTCCAC ATTGCCGCTC AGATCGCCTC AGGAATGGTG 
TACCTGGCGT CCCTTCATTT TGTCCACAGA GACCTGGCCA CAAGGAACTG TCTAGTGGGA 
GAAGGGCTGG TAGTGAAGAT CGGGGACTTT GGGATGTCAA GAGACATTTA CAGTACTGAC 
TACTACAGGG TCGGAGGCAG GACGATGCTG CCCATTCGCT GGATGCCACC GGAAAGCATT 
ATGTACAGGA AGTTCACCAC AGAGAGTGAC ATCTGGAGCT TCGGAGTCGT TTTGTGGGAA 
ATCTTCACCT ATGGCAAACA ACCCTGGTAT CAGCTATCCA ACAGTGAGGC CATTGAGTGC 
ATCACGCAGG GCCGAGAGCT GGAGCGGCCT CGCACCTGCC CAAAAGAAGT GCACCTCCTG 
ATGCAGGGCT GCTGGCAGAG AGAACCACAG CAAAGGTTGG TCATCAAGGA CATCTACAGT 
CGCCTCGTGG CCCTCGTCAA AAACCCACCC GTCTACCTGG ACATCCTGGA GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288285.1
CDS	142..2535
Translation	MADHRVAPVVGFLLFLVAPVWSGCPSACRCSFAMLQCLESDGITSIPALAAQESENVTEIYIESQPNLENITDVDLANYRELKNLTITDCGLVYISENAFQHNFKLQYVNLASNALTHISWRVFQSVTLLSLILRDNLLTCSCDIYWLQQWHRKRLNEIDSQQNCIYNGSQIPLDSFEMDNCSVPEVMIDPPTVTTQEGGNLTFTCRVTGVPTPTIHWRTEQLRSSWTLEQGIWGSTLEVVLHMRNVSSADNLHNLTCEAENRAGMGDAVVQLDIEFPVRIIYLKNPESQHHWCFPFAVDSNPPASIKWLYNNMPLTETRYAYTELIRDVYDGSQQHGCLFLNKPTHLNNGNYTIIVKNKLGRDQRTVRAKFMDNPFDPSDPEGIIPVLNDDPTAPTNQSTETEKIESRVFGVSVAVGLAVFACTFLLIMVVVINKCGQHSKFGIHRSSVLGTEDDLAVSLRFMNFGASPPSSDDGTLDSGLSSFVENPQYFCGIIKDKDMCVQHIKRKDIVLKWELGEGAFGKVYLAECANLCPDTDKMLVAIKTLKIANESTRQDFQREAELLTVLQHEHIVRFYGVCADGEPLAMVFEYMRHGDLNRFLRAHGPDARILDEMKVPPMGQLTLPQMLHIAAQIASGMVYLASLHFVHRDLATRNCLVGEGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESIMYRKFTTESDIWSFGVVLWEIFTYGKQPWYQLSNSEAIECITQGRELERPRTCPKEVHLLMQGCWQREPQQRLVIKDIYSRLVALVKNPPVYLDILE

Target ORF information:

RefSeq Version	NM_001301356.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio neurotrophic tyrosine kinase, receptor, type 1 (ntrk1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301356.1

ORF Insert Sequence:

ATGGCTGACC ATAGGGTGGC CCCGGTTGTG GGTTTTCTCC TTTTTTTGGT TGCACCGGTC 
TGGAGCGGAT GCCCAAGCGC ATGCCGCTGC TCCTTCGCTA TGCTACAATG CCTGGAGTCA 
GATGGCATCA CCAGCATCCC GGCGCTGGCA GCGCAGGAGA GTGAAAACGT CACTGAAATC 
TACATAGAGA GTCAACCCAA CCTGGAGAAC ATCACAGATG TAGACCTCGC CAACTACAGA 
GAACTGAAGA ATCTGACGAT CACAGATTGT GGGTTGGTGT ACATCTCTGA AAATGCCTTT 
CAGCATAACT TCAAGCTGCA GTATGTAAAC CTGGCCTCTA ATGCACTGAC GCACATCAGT 
TGGAGGGTGT TCCAATCTGT GACTCTATTG AGTCTGATTT TGAGGGACAA TCTGCTCACC 
TGCTCGTGTG ACATTTACTG GCTTCAGCAG TGGCACAGAA AAAGACTAAA CGAAATTGAT 
TCTCAGCAAA ATTGCATTTA CAATGGCAGC CAGATTCCGC TGGATTCATT CGAAATGGAT 
AACTGCAGTG TTCCTGAGGT CATGATTGAC CCACCGACAG TGACCACTCA AGAAGGTGGA 
AATTTGACAT TTACCTGCAG AGTGACTGGA GTTCCCACAC CGACGATCCA CTGGAGAACT 
GAGCAGCTTC GGTCCAGCTG GACCCTGGAG CAAGGAATCT GGGGATCAAC CCTGGAGGTG 
GTTCTGCACA TGAGAAATGT GTCTTCTGCT GACAACCTGC ACAACCTCAC CTGTGAAGCG 
GAGAATCGCG CTGGAATGGG AGATGCTGTG GTGCAGCTGG ACATTGAATT TCCAGTGCGG 
ATCATATATC TCAAGAACCC AGAATCTCAA CATCACTGGT GTTTCCCGTT CGCCGTAGAC 
AGCAATCCTC CCGCCAGCAT CAAATGGCTG TACAACAACA TGCCTCTCAC TGAGACCCGC 
TATGCCTACA CTGAACTCAT CAGAGACGTG TACGACGGCT CACAGCAACA CGGCTGTCTG 
TTCCTTAACA AACCCACTCA TCTCAACAAC GGCAACTACA CAATCATCGT GAAGAACAAA 
CTGGGCAGAG ACCAGAGAAC AGTCCGAGCC AAGTTCATGG ACAATCCTTT TGATCCCTCT 
GACCCGGAGG GCATCATCCC TGTGCTCAAT GACGACCCAA CAGCTCCCAC TAACCAATCA 
ACGGAGACGG AGAAAATAGA GAGCAGAGTG TTTGGGGTGT CAGTAGCTGT GGGCCTCGCT 
GTGTTTGCGT GCACATTTCT GCTCATCATG GTTGTTGTCA TTAATAAATG TGGACAGCAC 
TCCAAGTTTG GCATCCACCG TTCATCAGTT CTGGGCACCG AGGATGATCT GGCAGTGTCT 
CTCCGCTTCA TGAACTTCGG TGCTAGTCCT CCATCTTCAG ATGACGGCAC ACTGGATTCT 
GGCTTGTCCA GTTTTGTGGA GAACCCGCAA TATTTCTGTG GCATTATCAA AGATAAAGAC 
ATGTGTGTTC AGCACATTAA AAGAAAAGAC ATTGTTTTGA AGTGGGAACT GGGTGAAGGA 
GCTTTTGGCA AGGTTTATCT GGCTGAATGT GCCAATCTCT GTCCTGATAC TGACAAGATG 
CTGGTTGCTA TCAAGACTTT GAAAATAGCC AATGAGTCCA CCCGGCAGGA CTTCCAGCGC 
GAGGCTGAGC TGCTCACGGT GCTTCAGCAC GAACACATTG TGCGCTTCTA CGGTGTGTGC 
GCAGACGGAG AACCCCTGGC CATGGTGTTT GAGTACATGC GACACGGAGA CCTCAACCGC 
TTTCTAAGGG CTCACGGTCC CGATGCTCGT ATATTAGATG AGATGAAGGT TCCTCCGATG 
GGTCAGTTGA CTCTTCCTCA GATGCTCCAC ATTGCCGCTC AGATCGCCTC AGGAATGGTG 
TACCTGGCGT CCCTTCATTT TGTCCACAGA GACCTGGCCA CAAGGAACTG TCTAGTGGGA 
GAAGGGCTGG TAGTGAAGAT CGGGGACTTT GGGATGTCAA GAGACATTTA CAGTACTGAC 
TACTACAGGG TCGGAGGCAG GACGATGCTG CCCATTCGCT GGATGCCACC GGAAAGCATT 
ATGTACAGGA AGTTCACCAC AGAGAGTGAC ATCTGGAGCT TCGGAGTCGT TTTGTGGGAA 
ATCTTCACCT ATGGCAAACA ACCCTGGTAT CAGCTATCCA ACAGTGAGGC CATTGAGTGC 
ATCACGCAGG GCCGAGAGCT GGAGCGGCCT CGCACCTGCC CAAAAGAAGT GCACCTCCTG 
ATGCAGGGCT GCTGGCAGAG AGAACCACAG CAAAGGTTGG TCATCAAGGA CATCTACAGT 
CGCCTCGTGG CCCTCGTCAA AAACCCACCC GTCTACCTGG ACATCCTGGA GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A comprehensive analysis of neurotrophins and neurotrophin tyrosine kinase receptors expression during development of zebrafish.
The Journal of comparative neurology(2018 Jan)
Nittoli V,Sepe RM,Coppola U,D'Agostino Y,De Felice E,Palladino A,Vassalli QA,Locascio A,Ristoratore F,Spagnuolo A,D'Aniello S,Sordino P

Crypt cell markers in the olfactory organ of Poecilia reticulata: analysis and comparison with the fish model Danio rerio.
Brain structure & function222(7)3063-3074(2017 Sep)
Bettini S,Milani L,Lazzari M,Maurizii MG,Franceschini V

An ancient neurotrophin receptor code; a single Runx/Cbf? complex determines somatosensory neuron fate specification in zebrafish.
PLoS genetics13(7)e1006884(2017 Jul)
Gau P,Curtright A,Condon L,Raible DW,Dhaka A

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

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ntrk1 cDNA ORF clone, Danio rerio(zebrafish)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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