arl13b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	arl13b
Entrez Gene ID	286784
Full Name	ADP-ribosylation factor-like 13b
Synonyms	arl2l1,chunp6872,fc23g07,wu:fc23g07,zgc:123149
General protein information	Preferred Names ADP-ribosylation factor-like 13b Names ADP-ribosylation factor-like protein 13B ADP-ribosylation factor-like 2-like 1 ADP-ribosylation factor-like protein 2-like 1 ARL2-like protein 1 protein scorpion scorpion un-named hi459 unm hi459
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_173272.1	NP_775379.1	ADP-ribosylation factor-like protein 13B

Pathways from BioSystems

Homologies

	ARL13B	XP_001083714.2
Canis lupus familiaris (dog)	ARL13B	XP_005639397.1
Bos taurus (cattle)	ARL13B	XP_002684714.1
Danio rerio (zebrafish)	arl13b	NP_775379.1
Xenopus tropicalis (tropical clawed frog)	arl13b	NP_001184084.1
Homo sapiens (human)	ARL13B	NP_001167621.1
Gallus gallus (chicken)	ARL13B	XP_004938366.1
Pan troglodytes (chimpanzee)	ARL13B	XP_001137759.1
Mus musculus (house mouse)	Arl13b	NP_080853.3
Rattus norvegicus (Norway rat)	Arl13b	NP_001100571.1

Gene Ontology
Bibliography

Related articles in PubMed

Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of
Tavares B, Jacinto R, Sampaio P, Pestana S, Pinto A, Vaz A, Roxo-Rosa M, Gardner R, Lopes T, Schilling B, Henry I, Sa?de L, Lopes SS
eLife6(2017 Sep)

Role of ectonucleotide pyrophosphatase/phosphodiesterase 2 in the midline axis formation of zebrafish.
Frisca F, Colquhoun D, Goldshmit Y, ?nk? ML, P?bay A, Kaslin J
Scientific reports637678(2016 Nov)

Arl13b Interacts With Vangl2 to Regulate Cilia and Photoreceptor Outer Segment Length in Zebrafish.
Song P, Dudinsky L, Fogerty J, Gaivin R, Perkins BD
Investigative ophthalmology & visual science57(10)4517-26(2016 08)

Cilia-Associated Genes Play Differing Roles in Aminoglycoside-Induced Hair Cell Death in Zebrafish.
Stawicki TM, Hernandez L, Esterberg R, Linbo T, Owens KN, Shah AN, Thapa N, Roberts B, Moens CB, Rubel EW, Raible DW
G3 (Bethesda, Md.)6(7)2225-35(2016 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

loss of Arl13b leads to slow photoreceptor degeneration, but can be exacerbated by the loss of vangl2. Importantly, the data show that Arl13b can genetically and physically interact with Vangl2 and this association is important for normal photoreceptor structure.
Title: Arl13b Interacts With Vangl2 to Regulate Cilia and Photoreceptor Outer Segment Length in Zebrafish.

Arl13b is an important effector of ciliary membrane biogenesis and ciliary length regulation.
Title: A function for the Joubert syndrome protein Arl13b in ciliary membrane extension and ciliary length regulation.

Cilia localization is essential for in vivo functions of the Joubert syndrome protein arl13b.
Title: Cilia localization is essential for in vivo functions of the Joubert syndrome protein Arl13b/Scorpion.

The following arl13b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the arl13b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01103	NM_173272.1 Latest version!	Danio rerio ADP-ribosylation factor-like 13b (arl13b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

arl13b ( NM_173272.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_775379.1 Danio rerio ADP-ribosylation factor-like 13b (arl13b), mRNA.

Price & Availability↑

CloneID	ODa01103
Clone ID Related Accession (Same CDS sequence)	NM_173272.1
Accession Version	NM_173272.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1224bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Danio rerio(zebrafish)
Product	ADP-ribosylation factor-like protein 13B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF506213.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF506213.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGTTCAATC TGATGGCGAA CTGTTGCAAC TGGTTGAAAC GATGGAGAGA ACCTGCAAGG 
AAGGTGACAT TAGTAATGGT GGGATTGGAC AATGCTGGAA AAACGGCGAC AGTCAGAGGA 
ATCCAGGGAG AAAGCCCTTT AGATGTAGCA CCTACAGTGG GCTTTTCAAA GGTGGACCTG 
AAGCAGGGAA AGTTTGAGGT CACAATCTTT GACCTGGGTG GCGGGAAGCG TATTCGTGGC 
ATTTGGAAAA ACTACTACTC TGAATCTTAT GGAGTGGTGT TTGTTGTGGA CTCCAGTGAT 
GTCCAGAGAA TCCAGGAGAC CAGAGACACC ATGGCTGAGG TTCTCCGGCA TCCTCGTATT 
GCAGGCAAAC CTGTCTTAGT ACTGGCTAAT AAACAGGACC AAGATGGGGC AATGGCTGAA 
GCAGATATCA TTGAGACCCT GTCATTGGAG AAGCTAGTCA ACGAGAATAA ATGCCTTTGC 
CAGATTGAGC CCTGTTCAGC TGTCTTGGGT TATGGTAAAA AGGTTGACAA ATCCATCAAA 
AATGGCCTTA ACTGGCTCCT AAATAACATT GCCAAGGACT ATGAGGCAAT TTCAGAACGT 
GTGCAAAAAG ATACAGCCGA ACAGAAGGCT CAGGAAGAAC AAGACAAGAA AGAAAGAGCA 
GAGAGAGTTC GGCGGATCAG AGAAGAGAGA GACCGACAGG AACGGGAGGA AGCAGAGCGA 
GAAGGAAGGA CATTAAAAGA GGAAGAGCTA GATGATGTCA ACATGTTCAA CCCCTTTCAA 
CCAATAAACA ATGTTTTGAC TGAGAACCAA GACAGACTAA ACAGAGAAAA AGAGATGCAA 
AGACAGAGGG AAAATGGCCA GCAGGGCAGT GTGCAAGAAC AGATAGCACT TCAAGATGAG 
GAGGAAGAAG AGGAAGATGA AGAGAGTGAG AGACAGACTC CAGAAAGCAC AGAATCAGGA 
GCAGTGGACC AGACCAAAAA GAAAACTAGG AAACTACGGT TGAAACGCAA ACACAGAGTC 
GACCCTCTTA GGATGGAAGA AGCAGCACCC AAAAGCCCCA CGCCTCCTCC TCTGCCAGTT 
GGATGGGCAA CTCCTAAAGT TTCTAGGCTC CCCAAACTTG AGCCTCTTGG AGATACAAGG 
CATTCTGATT TCTATGGCAA ACCTCTCCCA CCTGTAGCAA TTCGGCAGAG GCCGAACAGC 
GATACTCATG ATGTCATTTC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775379.1
CDS	542..1765
Translation	MFNLMANCCNWLKRWREPARKVTLVMVGLDNAGKTATVRGIQGESPLDVAPTVGFSKVDLKQGKFEVTIFDLGGGKRIRGIWKNYYSESYGVVFVVDSSDVQRIQETRDTMAEVLRHPRIAGKPVLVLANKQDQDGAMAEADIIETLSLEKLVNENKCLCQIEPCSAVLGYGKKVDKSIKNGLNWLLNNIAKDYEAISERVQKDTAEQKAQEEQDKKERAERVRRIREERDRQEREEAEREGRTLKEEELDDVNMFNPFQPINNVLTENQDRLNREKEMQRQRENGQQGSVQEQIALQDEEEEEEDEESERQTPESTESGAVDQTKKKTRKLRLKRKHRVDPLRMEEAAPKSPTPPPLPVGWATPKVSRLPKLEPLGDTRHSDFYGKPLPPVAIRQRPNSDTHDVIS

Target ORF information:

RefSeq Version	NM_173272.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio ADP-ribosylation factor-like 13b (arl13b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173272.1

ORF Insert Sequence:

ATGTTCAATC TGATGGCGAA CTGTTGCAAC TGGTTGAAAC GATGGAGAGA ACCTGCAAGG 
AAGGTGACAT TAGTAATGGT GGGATTGGAC AATGCTGGAA AAACGGCGAC AGTCAGAGGA 
ATCCAGGGAG AAAGCCCTTT AGATGTAGCA CCTACAGTGG GCTTTTCAAA GGTGGACCTG 
AAGCAGGGAA AGTTTGAGGT CACAATCTTT GACCTGGGTG GCGGGAAGCG TATTCGTGGC 
ATTTGGAAAA ACTACTACTC TGAATCTTAT GGAGTGGTGT TTGTTGTGGA CTCCAGTGAT 
GTCCAGAGAA TCCAGGAGAC CAGAGACACC ATGGCTGAGG TTCTCCGGCA TCCTCGTATT 
GCAGGCAAAC CTGTCTTAGT ACTGGCTAAT AAACAGGACC AAGATGGGGC AATGGCTGAA 
GCAGATATCA TTGAGACCCT GTCATTGGAG AAGCTAGTCA ACGAGAATAA ATGCCTTTGC 
CAGATTGAGC CCTGTTCAGC TGTCTTGGGT TATGGTAAAA AGGTTGACAA ATCCATCAAA 
AATGGCCTTA ACTGGCTCCT AAATAACATT GCCAAGGACT ATGAGGCAAT TTCAGAACGT 
GTGCAAAAAG ATACAGCCGA ACAGAAGGCT CAGGAAGAAC AAGACAAGAA AGAAAGAGCA 
GAGAGAGTTC GGCGGATCAG AGAAGAGAGA GACCGACAGG AACGGGAGGA AGCAGAGCGA 
GAAGGAAGGA CATTAAAAGA GGAAGAGCTA GATGATGTCA ACATGTTCAA CCCCTTTCAA 
CCAATAAACA ATGTTTTGAC TGAGAACCAA GACAGACTAA ACAGAGAAAA AGAGATGCAA 
AGACAGAGGG AAAATGGCCA GCAGGGCAGT GTGCAAGAAC AGATAGCACT TCAAGATGAG 
GAGGAAGAAG AGGAAGATGA AGAGAGTGAG AGACAGACTC CAGAAAGCAC AGAATCAGGA 
GCAGTGGACC AGACCAAAAA GAAAACTAGG AAACTACGGT TGAAACGCAA ACACAGAGTC 
GACCCTCTTA GGATGGAAGA AGCAGCACCC AAAAGCCCCA CGCCTCCTCC TCTGCCAGTT 
GGATGGGCAA CTCCTAAAGT TTCTAGGCTC CCCAAACTTG AGCCTCTTGG AGATACAAGG 
CATTCTGATT TCTATGGCAA ACCTCTCCCA CCTGTAGCAA TTCGGCAGAG GCCGAACAGC 
GATACTCATG ATGTCATTTC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of
eLife6(2017 Sep)
Tavares B,Jacinto R,Sampaio P,Pestana S,Pinto A,Vaz A,Roxo-Rosa M,Gardner R,Lopes T,Schilling B,Henry I,Sa?de L,Lopes SS

Role of ectonucleotide pyrophosphatase/phosphodiesterase 2 in the midline axis formation of zebrafish.
Scientific reports637678(2016 Nov)
Frisca F,Colquhoun D,Goldshmit Y,?nk? ML,P?bay A,Kaslin J

Arl13b Interacts With Vangl2 to Regulate Cilia and Photoreceptor Outer Segment Length in Zebrafish.
Investigative ophthalmology & visual science57(10)4517-26(2016 08)
Song P,Dudinsky L,Fogerty J,Gaivin R,Perkins BD

Cilia-Associated Genes Play Differing Roles in Aminoglycoside-Induced Hair Cell Death in Zebrafish.
G3 (Bethesda, Md.)6(7)2225-35(2016 07)
Stawicki TM,Hernandez L,Esterberg R,Linbo T,Owens KN,Shah AN,Thapa N,Roberts B,Moens CB,Rubel EW,Raible DW

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arl13b cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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