her4.4 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	her4.4
Entrez Gene ID	100149066
Full Name	hairy-related 4, tandem duplicate 4
Synonyms	si:ch73-21g5.5
General protein information	Preferred Names hairy-related 4, tandem duplicate 4 Names hairy-related 4, tandem duplicate 4 hairy-related 4.2-like
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001128390.1	NP_001121862.1	hairy-related 4, tandem duplicate 4

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	LOC100149066	NP_001121862.1
Homo sapiens (human)	HES5	NP_001010926.1
Mus musculus (house mouse)	Hes5	NP_034549.1
Danio rerio (zebrafish)	her4.2	NP_571165.3
Danio rerio (zebrafish)	her4.3	NP_001154880.1
Xenopus tropicalis (tropical clawed frog)	hes5	XP_004916212.1
Pan troglodytes (chimpanzee)	HES5	XP_524847.2
Canis lupus familiaris (dog)	HES5	XP_546734.2
Bos taurus (cattle)	HES5	NP_001098937.1
Rattus norvegicus (Norway rat)	Hes5	NP_077359.1
Gallus gallus (chicken)	HES5	NP_001012713.1
Xenopus tropicalis (tropical clawed frog)	hes5.1	NP_001037880.1
Danio rerio (zebrafish)	LOC100149863	NP_001096598.1
Danio rerio (zebrafish)	LOC100148329	NP_001154881.1

Gene Ontology
Bibliography

Related articles in PubMed

Tracking the fate of her4 expressing cells in the regenerating retina using her4:Kaede zebrafish.
Wilson SG, Wen W, Pillai-Kastoori L, Morris AC
Experimental eye research14575-87(2016 04)

Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches.
Diotel N, Rodriguez Viales R, Armant O, M?rz M, Ferg M, Rastegar S, Str?hle U
The Journal of comparative neurology523(8)1202-21(2015 Jun)

Comparative and evolutionary analysis of the HES/HEY gene family reveal exon/intron loss and teleost specific duplication events.
Zhou M, Yan J, Ma Z, Zhou Y, Abbood NN, Liu J, Su L, Jia H, Guo AY
PloS one7(7)e40649(2012)

Her4 is necessary for establishing peripheral projections of the trigeminal ganglia in zebrafish.
So JH, Chun HS, Bae YK, Kim HS, Park YM, Huh TL, Chitnis AB, Kim CH, Yeo SY
Biochemical and biophysical research communications379(1)22-6(2009 Jan)

Two linked hairy/Enhancer of split-related zebrafish genes, her1 and her7, function together to refine alternating somite boundaries.
Henry CA, Urban MK, Dill KK, Merlie JP, Page MF, Kimmel CB, Amacher SL
Development (Cambridge, England)129(15)3693-704(2002 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following her4.4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the her4.4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa04218	NM_001128390.1 Latest version!	Danio rerio hairy-related 4, tandem duplicate 4 (her4.4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

her4.4 ( NM_001128390.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001121862.1 Danio rerio hairy-related 4, tandem duplicate 4 (her4.4), mRNA.

Price & Availability↑

CloneID	ODa04218
Clone ID Related Accession (Same CDS sequence)	NM_001128390.1
Accession Version	NM_001128390.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-07-05
Organism	Danio rerio(zebrafish)
Product	hairy-related 4, tandem duplicate 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CU062502.10. On Jul 31, 2008 this sequence version replaced XM_001921267.1. ##Evidence-Data-START## Transcript exon combination :: BC071288.1, GW710422.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505374, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END##

ATGACTCCTA CAATCACTGG ATCAATCAGC AGCAGAGAAA CTCTACTGAC AAACAAGCTG 
AGAAAGCCCA TGGTGGAGAA GATCCGCCGA GAGCGAATCA ACAGCAGCAT CGAGAAGCTC 
AAGACTCTTC TGGCTCAAGA GTTCGTCAAG CAGCAGCCCG ACTCCAGACA GGAGAAAGCT 
GATATCCTGG AGATGACGCT TGATTTCTTG AGACGCTCTC AGAAAAGCAG TGCGGCTGGT 
GACGGACGCT CCAGATGTGT GCAGGAGGCC GTCAGCTTTC TGTCTCAGTG CCCAGTGCAG 
ACGCAGAGCC ACACAAGACT GATGAAGCTC TTCCTGCACA TGCAGACTCC TGCAGACCAG 
CACACACGTG TGGACAATCC TCAGACCACT GAAAAACACG CAAACAGCAG CGCCAAACAA 
CACACTCCAG CCCGCAGTCA CATCTGGAGA CCCTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001121862.1
CDS	51..509
Translation	MTPTITGSISSRETLLTNKLRKPMVEKIRRERINSSIEKLKTLLAQEFVKQQPDSRQEKADILEMTLDFLRRSQKSSAAGDGRSRCVQEAVSFLSQCPVQTQSHTRLMKLFLHMQTPADQHTRVDNPQTTEKHANSSAKQHTPARSHIWRPW

Target ORF information:

RefSeq Version	NM_001128390.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio hairy-related 4, tandem duplicate 4 (her4.4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128390.1

ORF Insert Sequence:

ATGACTCCTA CAATCACTGG ATCAATCAGC AGCAGAGAAA CTCTACTGAC AAACAAGCTG 
AGAAAGCCCA TGGTGGAGAA GATCCGCCGA GAGCGAATCA ACAGCAGCAT CGAGAAGCTC 
AAGACTCTTC TGGCTCAAGA GTTCGTCAAG CAGCAGCCCG ACTCCAGACA GGAGAAAGCT 
GATATCCTGG AGATGACGCT TGATTTCTTG AGACGCTCTC AGAAAAGCAG TGCGGCTGGT 
GACGGACGCT CCAGATGTGT GCAGGAGGCC GTCAGCTTTC TGTCTCAGTG CCCAGTGCAG 
ACGCAGAGCC ACACAAGACT GATGAAGCTC TTCCTGCACA TGCAGACTCC TGCAGACCAG 
CACACACGTG TGGACAATCC TCAGACCACT GAAAAACACG CAAACAGCAG CGCCAAACAA 
CACACTCCAG CCCGCAGTCA CATCTGGAGA CCCTGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tracking the fate of her4 expressing cells in the regenerating retina using her4:Kaede zebrafish.
Experimental eye research14575-87(2016 04)
Wilson SG,Wen W,Pillai-Kastoori L,Morris AC

Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches.
The Journal of comparative neurology523(8)1202-21(2015 Jun)
Diotel N,Rodriguez Viales R,Armant O,M?rz M,Ferg M,Rastegar S,Str?hle U

Comparative and evolutionary analysis of the HES/HEY gene family reveal exon/intron loss and teleost specific duplication events.
PloS one7(7)e40649(2012)
Zhou M,Yan J,Ma Z,Zhou Y,Abbood NN,Liu J,Su L,Jia H,Guo AY

Her4 is necessary for establishing peripheral projections of the trigeminal ganglia in zebrafish.
Biochemical and biophysical research communications379(1)22-6(2009 Jan)
So JH,Chun HS,Bae YK,Kim HS,Park YM,Huh TL,Chitnis AB,Kim CH,Yeo SY

Two linked hairy/Enhancer of split-related zebrafish genes, her1 and her7, function together to refine alternating somite boundaries.
Development (Cambridge, England)129(15)3693-704(2002 Aug)
Henry CA,Urban MK,Dill KK,Merlie JP,Page MF,Kimmel CB,Amacher SL