Gene Symbol | SREBF1 |
Entrez Gene ID | 100860908 |
Full Name | sterol regulatory element binding transcription factor 1 |
Synonyms | SREBP-1 |
Gene Type | protein-coding |
Organism | Capra hircus(goat) |
ORF » Species Summary » Capra hircus » SREBF1 cDNA ORF clone
Gene Symbol | SREBF1 |
Entrez Gene ID | 100860908 |
Full Name | sterol regulatory element binding transcription factor 1 |
Synonyms | SREBP-1 |
Gene Type | protein-coding |
Organism | Capra hircus(goat) |
mRNA | Protein | Name |
---|---|---|
NM_001285755.1 | NP_001272684.1 | sterol regulatory element-binding protein 1 |
Acyl-CoA synthetase short-chain family member 2 (ACSS2) is regulated by SREBP-1 and plays a role in fatty acid synthesis in caprine mammary epithelial cells.
Xu H, Luo J, Ma G, Zhang X, Yao D, Li M, Loor JJ
Journal of cellular physiology233(2)1005-1016(2018 Feb)
SCD1 Alters Long-Chain Fatty Acid (LCFA) Composition and Its Expression Is Directly Regulated by SREBP-1 and PPAR? 1 in Dairy Goat Mammary Cells.
Yao D, Luo J, He Q, Shi H, Li J, Wang H, Xu H, Chen Z, Yi Y, Loor JJ
Journal of cellular physiology232(3)635-649(2017 Mar)
Overexpression of SREBP1 (sterol regulatory element binding protein 1) promotes de novo fatty acid synthesis and triacylglycerol accumulation in goat mammary epithelial cells.
Xu HF, Luo J, Zhao WS, Yang YC, Tian HB, Shi HB, Bionaz M
Journal of dairy science99(1)783-95(2016 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
SREBP-1 may regulate mammary gland fatty acid and triacylglycerol synthesis by regulating the expression of ACSS2.
Title: Acyl-CoA synthetase short-chain family member 2 (ACSS2) is regulated by SREBP-1 and plays a role in fatty acid synthesis in caprine mammary epithelial cells.
SCD1 could markedly affect the fatty acid composition and rate of triacylglycerol synthesis through direct regulation via SREBP-1 and PPARG1.
Title: SCD1 Alters Long-Chain Fatty Acid (LCFA) Composition and Its Expression Is Directly Regulated by SREBP-1 and PPAR? 1 in Dairy Goat Mammary Cells.
Overexpression of nSREBP1 increased the expression of genes related to milk fat synthesis, cellular triacylglycerol content, and the amounts of C16:0 and C18:1.
Title: Overexpression of SREBP1 (sterol regulatory element binding protein 1) promotes de novo fatty acid synthesis and triacylglycerol accumulation in goat mammary epithelial cells.
The following SREBF1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SREBF1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa156930 | |
Clone ID Related Accession (Same CDS sequence) | NM_001285755.1 | |
Accession Version | NM_001285755.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3441bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-23 | |
Organism | Capra hircus(goat) | |
Product | sterol regulatory element-binding protein 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from HM443643.1. On Oct 23, 2013 this sequence version replaced XM_005694253.1. ##Evidence-Data-START## Transcript exon combination :: HM443643.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01086873, SAMN01086875 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGACGAGC CACCCTTCAA CGAAGCGGCC TTGGAGCTGG CGCTGGCCGA GCCGTGCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001272684.1 |
CDS | 1..3441 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001285755.1 |
1 | ATGGACGAGC CACCCTTCAA CGAAGCGGCC TTGGAGCTGG CGCTGGCCGA GCCGTGCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Acyl-CoA synthetase short-chain family member 2 (ACSS2) is regulated by SREBP-1 and plays a role in fatty acid synthesis in caprine mammary epithelial cells. |
SCD1 Alters Long-Chain Fatty Acid (LCFA) Composition and Its Expression Is Directly Regulated by SREBP-1 and PPAR? 1 in Dairy Goat Mammary Cells. |
Overexpression of SREBP1 (sterol regulatory element binding protein 1) promotes de novo fatty acid synthesis and triacylglycerol accumulation in goat mammary epithelial cells. |