TAS1R3 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	TAS1R3
Entrez Gene ID	489594
Full Name	taste 1 receptor member 3
General protein information	Preferred Names taste 1 receptor member 3 Names taste receptor type 1 member 3 sweet taste receptor T1R3 taste receptor, type 1, member 3
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001031821.1	NP_001026991.1	taste receptor type 1 member 3 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TAS1R3	XP_003307796.1
Gallus gallus (chicken)	TAS1R3	XP_425740.2
Danio rerio (zebrafish)	tas1r3	NP_001034717.1
Canis lupus familiaris (dog)	TAS1R3	NP_001026991.1
Mus musculus (house mouse)	Tas1r3	NP_114078.1
Rattus norvegicus (Norway rat)	Tas1r3	NP_570831.1
Homo sapiens (human)	TAS1R3	NP_689414.1
	TAS1R3	XP_001094084.2

Gene Ontology
Bibliography

Related articles in PubMed

Sodium/glucose cotransporter-1, sweet receptor, and disaccharidase expression in the intestine of the domestic dog and cat: two species of different dietary habit.
Batchelor DJ, Al-Rammahi M, Moran AW, Brand JG, Li X, Haskins M, German AJ, Shirazi-Beechey SP
American journal of physiology. Regulatory, integrative and comparative physiology300(1)R67-75(2011 Jan)

Cats lack a sweet taste receptor.
Li X, Li W, Wang H, Bayley DL, Cao J, Reed DR, Bachmanov AA, Huang L, Legrand-Defretin V, Beauchamp GK, Brand JG
The Journal of nutrition136(7 Suppl)1932S-1934S(2006 Jul)

Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar.
Li X, Li W, Wang H, Cao J, Maehashi K, Huang L, Bachmanov AA, Reed DR, Legrand-Defretin V, Beauchamp GK, Brand JG
PLoS genetics1(1)27-35(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Both cats and dogs express T1R3 in a subset of intestinal epithelial cells, and dogs, but not cats, express T1R2.
Title: Sodium/glucose cotransporter-1, sweet receptor, and disaccharidase expression in the intestine of the domestic dog and cat: two species of different dietary habit.

The following TAS1R3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TAS1R3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe00218	NM_001031821.1 Latest version!	Canis lupus familiaris taste 1 receptor member 3 (TAS1R3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$510.30 $729.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TAS1R3 ( NM_001031821.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001026991.1 Canis lupus familiaris taste 1 receptor member 3 (TAS1R3), mRNA.

Price & Availability↑

CloneID	OCe00218
Clone ID Related Accession (Same CDS sequence)	NM_001031821.1
Accession Version	NM_001031821.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2538bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Canis lupus familiaris(dog)
Product	taste receptor type 1 member 3 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY916759.1. On Aug 19, 2005 this sequence version replaced XM_546714.1. ##Evidence-Data-START## Transcript exon combination :: AY916759.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCAGGCC TGATGCTCCT GAGCCTCATG GCTCTCTTGG GCCTTGGAGC AGGCGCCCCA 
TTGTGCTTAT CCCGGCAGCT CAGGATGCAA GGGGACTATG TGCTGGGCGG GCTCTTCCCC 
CTGGGCACAG CTGAGGACAC AGGTCTCAGT GACAGGACAC AGCCCAATGC CACTGTGTGC 
ACCAGGTTCT CGTCCCTCGG CCTGCTCTGG GCGCTGGCCA TGAAGATGGC GGTGGAGGAG 
GTCAACAACA GGTCCACGCT GCTGCCAGGA CTGCGCCTGG GCTACGACCT CTTTGACACA 
TGTTCGGAGC CTGTGGTGGC CATGAAGCCC AGCCTCATGT TCATGGCCAA AGCGGGCAGC 
TGCGACATCG CCGCCTACTG CAACTACACG CAGTACCAGC CCCGTGTGCT GGCAGTCATT 
GGGCCACACT CATCTGAGCT CGCCCTCATC ACCGGCAAGT TCTTCAGCTT CTTCCTCATG 
CCTCAGGTCA GCTACGGGGC CAGCACCGAC CGGCTGAGCA ACCGGGAGAC GTTCCCATCC 
TTCTTCCGCA CGGTGTCCAG CGACCGCGTA CAGGCAGTGG CCATGGTGGA GCTGCTGCAG 
GAGCTTGGCT GGAACTGGGT GGCTGCAGTG GGCAGCGATG ACGAGTATGG CCGGCAGGGC 
CTGAGCCTCT TCTCCAGCCT GGCCAATGCC AGGGGCATCT GTATTGCGCA TGAGGGCCTG 
GTGCCATTGC CGCACACGAG TAGCCTGCGG CTGGGCACTG TCCAGGGCCT ACTGCACCAG 
GTAAACCAGA GCAGCGTGCA GGTGGTGGTG CTTTTCTCTT CCACTCGTGC TGCCCGCACC 
CTCTTCAGCT ACAGCATCCA CTGCAGGCTC TCGCCCAAGG TTTGGGTGGC CAGTGAGGCC 
TGGCTGACCT CGGACCTGGT CATGACGCTG CCTGGCATGG CTGAGGTGGG CACCGTGCTT 
GGCTTTCTGC AGCAGGGCGC CCCAATACCC GAGTTCCCAT CCTATGTGCA GACCTGCCTG 
GCCCTGGCTG CTGACCCTGC CTTTTGCGCC TCACTGGATG CAGAGCAGCC GGGCCTGGAA 
GAGCACGTGG TGGGGCCCCG CTGTCCCCAG TGTGACCACG TCACTCTGGA GGCTATGTCT 
GCAGGGCTGC TGCACCACCA GACCTTCGCG GCCTACGCAG CCGTGTATGG CGTGGCCCAG 
GCCCTCCACA ACACACTGCT CTGCAATGCC TCAGGCTGCC CCCCACGGGA GCCAGTGCGG 
CCCTGGCAGC TCCTAGAAAA CATGTACAAC TTGACCTTCC GTGTGCGCGG CTTAGCACTG 
CAGTTCGATG CCAGGGGGAA CGTGAATATG GATTATGACC TGAAACTGTG GGTGTGGCGG 
GACCTGAAGC CCGAGTTGCG CACCGTAGGT GCCTTCAACG GCCGCCTGAA GGTCTGGCAC 
TCCCAGATGT CCTGGCACAC ACCTGGGAAC CAGCGGCCCG TGTCCCAGTG CTCCCGGCAG 
TGCGGGGAGG GCCAGGTGCG CCGTGTGAAG GGCTTCCACT CCTGCTGCTA TGACTGCGTG 
GACTGCAAGG CGGGCACCTA TCAGCGCAGC CCAGATGACC TCCTCTGCAC CCAGTGTGAC 
CAGAACCAGT GGTCCCCAGA CCGGAGCACA CGCTGCTTCC CCCGCAGGCT CACTTTCCTG 
GCATGGGGGC AGCCGGCTGT GCTGGTGCTG CTTATACTGC TGGCTCTGGC GCTGGGCCTG 
GTGCTGGTGG CCCTGGGGCT CTTTATTAGG CACCGGGACA GCCCACTGGT TCAGGCCTCA 
GGGGGGCCAC GGGCCTGCTT TGGCTTGGCC TGCCTGGGCC TTGTCTGCCT CAGTGTCCTT 
CTGTTCCCTG GCCAGCCGGG CCCTGCCAGC TGCCTGGCCC AGCAGCCACT GCTTCACCTT 
CCACTCACTG GCTGTCTGAG CACACTTTTC CTGCAAGCGG CCCAGATATT TGTGGGTTCA 
GAGCTGCCAT CAAGCTGGGC AGATCAGCTG CGTAGGTGCC TGCAGGGGCC CTGGGCCTGG 
TTGCTGGTGC TGCTTGCTTT GCTGGCGGAA GCGGCATTAT GTGCCTGGTA CCTGGTGGCC 
TTTCCACCAG AGGTGGTGAC AGACTGGTGG GTGCTACCCA CGCAAGTGCT GGTGCACTGC 
CGAATGCGCT CCTGGATCAG CTTTGGCCTA TTGCATGCCA TCAATGCCAT GCTGGCCTTC 
CTCTGCTTCC TGGGCACGTT CTTGGTGCAG AGCCGGCCAG GCCGCTACAA TGGCGCCCGG 
GGTCTCACTT TTGCCATGCT GGCCTACTTC ATCACCTGGA TCTCCTTTGT CCCTCTCTTT 
GCCAATGTGC ATGTGGCCTA CCAGCCCACT GTGCAGATGG CCGCCATCCT CCTCTGTGCC 
CTGGGCATCC TGGCCACCTT CCACCTGCCC AAGTGCTACC TGCTGCTGCA GCAGCTGGAG 
CTCAACAACC CGGAGTTCTT CCTAGGAGAT GATGCCAGAG GACAGGGCAG CAGTGGTAGT 
GGGGGGAAGG AGACTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001026991.1
CDS	1..2538
Translation	MAGLMLLSLMALLGLGAGAPLCLSRQLRMQGDYVLGGLFPLGTAEDTGLSDRTQPNATVCTRFSSLGLLWALAMKMAVEEVNNRSTLLPGLRLGYDLFDTCSEPVVAMKPSLMFMAKAGSCDIAAYCNYTQYQPRVLAVIGPHSSELALITGKFFSFFLMPQVSYGASTDRLSNRETFPSFFRTVSSDRVQAVAMVELLQELGWNWVAAVGSDDEYGRQGLSLFSSLANARGICIAHEGLVPLPHTSSLRLGTVQGLLHQVNQSSVQVVVLFSSTRAARTLFSYSIHCRLSPKVWVASEAWLTSDLVMTLPGMAEVGTVLGFLQQGAPIPEFPSYVQTCLALAADPAFCASLDAEQPGLEEHVVGPRCPQCDHVTLEAMSAGLLHHQTFAAYAAVYGVAQALHNTLLCNASGCPPREPVRPWQLLENMYNLTFRVRGLALQFDARGNVNMDYDLKLWVWRDLKPELRTVGAFNGRLKVWHSQMSWHTPGNQRPVSQCSRQCGEGQVRRVKGFHSCCYDCVDCKAGTYQRSPDDLLCTQCDQNQWSPDRSTRCFPRRLTFLAWGQPAVLVLLILLALALGLVLVALGLFIRHRDSPLVQASGGPRACFGLACLGLVCLSVLLFPGQPGPASCLAQQPLLHLPLTGCLSTLFLQAAQIFVGSELPSSWADQLRRCLQGPWAWLLVLLALLAEAALCAWYLVAFPPEVVTDWWVLPTQVLVHCRMRSWISFGLLHAINAMLAFLCFLGTFLVQSRPGRYNGARGLTFAMLAYFITWISFVPLFANVHVAYQPTVQMAAILLCALGILATFHLPKCYLLLQQLELNNPEFFLGDDARGQGSSGSGGKET

Target ORF information:

RefSeq Version	NM_001031821.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris taste 1 receptor member 3 (TAS1R3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001031821.1

ORF Insert Sequence:

ATGGCAGGCC TGATGCTCCT GAGCCTCATG GCTCTCTTGG GCCTTGGAGC AGGCGCCCCA 
TTGTGCTTAT CCCGGCAGCT CAGGATGCAA GGGGACTATG TGCTGGGCGG GCTCTTCCCC 
CTGGGCACAG CTGAGGACAC AGGTCTCAGT GACAGGACAC AGCCCAATGC CACTGTGTGC 
ACCAGGTTCT CGTCCCTCGG CCTGCTCTGG GCGCTGGCCA TGAAGATGGC GGTGGAGGAG 
GTCAACAACA GGTCCACGCT GCTGCCAGGA CTGCGCCTGG GCTACGACCT CTTTGACACA 
TGTTCGGAGC CTGTGGTGGC CATGAAGCCC AGCCTCATGT TCATGGCCAA AGCGGGCAGC 
TGCGACATCG CCGCCTACTG CAACTACACG CAGTACCAGC CCCGTGTGCT GGCAGTCATT 
GGGCCACACT CATCTGAGCT CGCCCTCATC ACCGGCAAGT TCTTCAGCTT CTTCCTCATG 
CCTCAGGTCA GCTACGGGGC CAGCACCGAC CGGCTGAGCA ACCGGGAGAC GTTCCCATCC 
TTCTTCCGCA CGGTGTCCAG CGACCGCGTA CAGGCAGTGG CCATGGTGGA GCTGCTGCAG 
GAGCTTGGCT GGAACTGGGT GGCTGCAGTG GGCAGCGATG ACGAGTATGG CCGGCAGGGC 
CTGAGCCTCT TCTCCAGCCT GGCCAATGCC AGGGGCATCT GTATTGCGCA TGAGGGCCTG 
GTGCCATTGC CGCACACGAG TAGCCTGCGG CTGGGCACTG TCCAGGGCCT ACTGCACCAG 
GTAAACCAGA GCAGCGTGCA GGTGGTGGTG CTTTTCTCTT CCACTCGTGC TGCCCGCACC 
CTCTTCAGCT ACAGCATCCA CTGCAGGCTC TCGCCCAAGG TTTGGGTGGC CAGTGAGGCC 
TGGCTGACCT CGGACCTGGT CATGACGCTG CCTGGCATGG CTGAGGTGGG CACCGTGCTT 
GGCTTTCTGC AGCAGGGCGC CCCAATACCC GAGTTCCCAT CCTATGTGCA GACCTGCCTG 
GCCCTGGCTG CTGACCCTGC CTTTTGCGCC TCACTGGATG CAGAGCAGCC GGGCCTGGAA 
GAGCACGTGG TGGGGCCCCG CTGTCCCCAG TGTGACCACG TCACTCTGGA GGCTATGTCT 
GCAGGGCTGC TGCACCACCA GACCTTCGCG GCCTACGCAG CCGTGTATGG CGTGGCCCAG 
GCCCTCCACA ACACACTGCT CTGCAATGCC TCAGGCTGCC CCCCACGGGA GCCAGTGCGG 
CCCTGGCAGC TCCTAGAAAA CATGTACAAC TTGACCTTCC GTGTGCGCGG CTTAGCACTG 
CAGTTCGATG CCAGGGGGAA CGTGAATATG GATTATGACC TGAAACTGTG GGTGTGGCGG 
GACCTGAAGC CCGAGTTGCG CACCGTAGGT GCCTTCAACG GCCGCCTGAA GGTCTGGCAC 
TCCCAGATGT CCTGGCACAC ACCTGGGAAC CAGCGGCCCG TGTCCCAGTG CTCCCGGCAG 
TGCGGGGAGG GCCAGGTGCG CCGTGTGAAG GGCTTCCACT CCTGCTGCTA TGACTGCGTG 
GACTGCAAGG CGGGCACCTA TCAGCGCAGC CCAGATGACC TCCTCTGCAC CCAGTGTGAC 
CAGAACCAGT GGTCCCCAGA CCGGAGCACA CGCTGCTTCC CCCGCAGGCT CACTTTCCTG 
GCATGGGGGC AGCCGGCTGT GCTGGTGCTG CTTATACTGC TGGCTCTGGC GCTGGGCCTG 
GTGCTGGTGG CCCTGGGGCT CTTTATTAGG CACCGGGACA GCCCACTGGT TCAGGCCTCA 
GGGGGGCCAC GGGCCTGCTT TGGCTTGGCC TGCCTGGGCC TTGTCTGCCT CAGTGTCCTT 
CTGTTCCCTG GCCAGCCGGG CCCTGCCAGC TGCCTGGCCC AGCAGCCACT GCTTCACCTT 
CCACTCACTG GCTGTCTGAG CACACTTTTC CTGCAAGCGG CCCAGATATT TGTGGGTTCA 
GAGCTGCCAT CAAGCTGGGC AGATCAGCTG CGTAGGTGCC TGCAGGGGCC CTGGGCCTGG 
TTGCTGGTGC TGCTTGCTTT GCTGGCGGAA GCGGCATTAT GTGCCTGGTA CCTGGTGGCC 
TTTCCACCAG AGGTGGTGAC AGACTGGTGG GTGCTACCCA CGCAAGTGCT GGTGCACTGC 
CGAATGCGCT CCTGGATCAG CTTTGGCCTA TTGCATGCCA TCAATGCCAT GCTGGCCTTC 
CTCTGCTTCC TGGGCACGTT CTTGGTGCAG AGCCGGCCAG GCCGCTACAA TGGCGCCCGG 
GGTCTCACTT TTGCCATGCT GGCCTACTTC ATCACCTGGA TCTCCTTTGT CCCTCTCTTT 
GCCAATGTGC ATGTGGCCTA CCAGCCCACT GTGCAGATGG CCGCCATCCT CCTCTGTGCC 
CTGGGCATCC TGGCCACCTT CCACCTGCCC AAGTGCTACC TGCTGCTGCA GCAGCTGGAG 
CTCAACAACC CGGAGTTCTT CCTAGGAGAT GATGCCAGAG GACAGGGCAG CAGTGGTAGT 
GGGGGGAAGG AGACTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Sodium/glucose cotransporter-1, sweet receptor, and disaccharidase expression in the intestine of the domestic dog and cat: two species of different dietary habit.
American journal of physiology. Regulatory, integrative and comparative physiology300(1)R67-75(2011 Jan)
Batchelor DJ,Al-Rammahi M,Moran AW,Brand JG,Li X,Haskins M,German AJ,Shirazi-Beechey SP

Cats lack a sweet taste receptor.
The Journal of nutrition136(7 Suppl)1932S-1934S(2006 Jul)
Li X,Li W,Wang H,Bayley DL,Cao J,Reed DR,Bachmanov AA,Huang L,Legrand-Defretin V,Beauchamp GK,Brand JG

Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar.
PLoS genetics1(1)27-35(2005 Jul)
Li X,Li W,Wang H,Cao J,Maehashi K,Huang L,Bachmanov AA,Reed DR,Legrand-Defretin V,Beauchamp GK,Brand JG

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TAS1R3 cDNA ORF clone, Canis lupus familiaris(dog)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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