Gene Symbol | TGFB1 |
Entrez Gene ID | 403998 |
Full Name | transforming growth factor beta 1 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » TGFB1 cDNA ORF clone
Gene Symbol | TGFB1 |
Entrez Gene ID | 403998 |
Full Name | transforming growth factor beta 1 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001003309.1 | NP_001003309.1 | transforming growth factor beta-1 proprotein precursor |
Xenopus tropicalis (tropical clawed frog) | tgfb1 | XP_002939433.1 |
Homo sapiens (human) | TGFB1 | NP_000651.3 |
Pan troglodytes (chimpanzee) | TGFB1 | XP_512687.2 |
Danio rerio (zebrafish) | tgfb1a | NP_878293.1 |
Canis lupus familiaris (dog) | TGFB1 | NP_001003309.1 |
Danio rerio (zebrafish) | LOC563884 | XP_692338.3 |
Bos taurus (cattle) | TGFB1 | NP_001159540.1 |
Mus musculus (house mouse) | Tgfb1 | NP_035707.1 |
Rattus norvegicus (Norway rat) | Tgfb1 | NP_067589.1 |
CD61 promotes the differentiation of canine ADMSCs into PGC-like cells through modulation of TGF-? signaling.
Fang J, Wei Y, Lv C, Peng S, Zhao S, Hua J
Scientific reports743851(2017 Mar)
Chronic obstructive sleep apnea accelerates pulmonary remodeling via TGF-?/miR-185/CoLA1 signaling in a canine model.
Ding X, Yu C, Liu Y, Yan S, Li W, Wang D, Sun L, Han Y, Li M, Zhang S, Yun F, Zhao H, Li Y
Oncotarget7(36)57545-57555(2016 Sep)
Apoptosis and abundance of Bcl-2 family and transforming growth factor ?1 signaling proteins in canine myxomatous mitral valves.
Surachetpong S, Jiranantasak T, Rungsipipat A, Orton EC
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology15(3)171-80(2013 Sep)
Celastrol inhibits TGF-?1-induced epithelial-mesenchymal transition by inhibiting Snail and regulating E-cadherin expression.
Kang H, Lee M, Jang SW
Biochemical and biophysical research communications437(4)550-6(2013 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
TGFbeta1 signaling through the canonical SMAD pathway is increased in myxomatous mitral valves, but does not apparently mediate interstitial cell apoptosis in canine MMVD.
Title: Apoptosis and abundance of Bcl-2 family and transforming growth factor ?1 signaling proteins in canine myxomatous mitral valves.
celastrol downregulates Snail expression, thereby inhibiting TGF-beta1-induced EMT in MDCK and A549 cells
Title: Celastrol inhibits TGF-?1-induced epithelial-mesenchymal transition by inhibiting Snail and regulating E-cadherin expression.
IL-6 markedly decreased the nuclear concentration of a TGF-beta signaling transducer, Smad 2/3.
Title: IL-6 restores dendritic cell maturation inhibited by tumor-derived TGF-? through interfering Smad 2/3 nuclear translocation.
PAK2 negatively modulate TGF-beta signaling by attenuating the receptor-Smad interaction and thus Smad activation
Title: p21-Activated kinase 2 (PAK2) inhibits TGF-? signaling in Madin-Darby canine kidney (MDCK) epithelial cells by interfering with the receptor-Smad interaction.
Ostectomy healing with or without platelet-rich plasma as indicated by radiography and expression of PDGF and TGF-beta expression are reported.
Title: Healing and expression of growth factors (TGF-? and PDGF) in canine radial ostectomy gap containing platelet-rich plasma.
The following TGFB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TGFB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00341 | |
Clone ID Related Accession (Same CDS sequence) | NM_001003309.1 | |
Accession Version | NM_001003309.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1173bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-17 | |
Organism | Canis lupus familiaris(dog) | |
Product | transforming growth factor beta-1 proprotein precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L34956.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L34956.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCGCCCT CCGGGCTGCG GCTGCTGCCG CTGCTGCTGC CGCTGCTGCG GCTACTAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001003309.1 |
CDS | 58..1230 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001003309.1 |
1 | ATGCCGCCCT CCGGGCTGCG GCTGCTGCCG CTGCTGCTGC CGCTGCTGCG GCTACTAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CD61 promotes the differentiation of canine ADMSCs into PGC-like cells through modulation of TGF-? signaling. |
Chronic obstructive sleep apnea accelerates pulmonary remodeling via TGF-?/miR-185/CoLA1 signaling in a canine model. |
Apoptosis and abundance of Bcl-2 family and transforming growth factor ?1 signaling proteins in canine myxomatous mitral valves. |
Celastrol inhibits TGF-?1-induced epithelial-mesenchymal transition by inhibiting Snail and regulating E-cadherin expression. |