Gene Symbol | CD4 |
Entrez Gene ID | 403931 |
Full Name | CD4 molecule |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » CD4 cDNA ORF clone
Gene Symbol | CD4 |
Entrez Gene ID | 403931 |
Full Name | CD4 molecule |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001003252.1 | NP_001003252.1 | T-cell surface glycoprotein CD4 precursor |
Rattus norvegicus (Norway rat) | Cd4 | NP_036837.1 |
Bos taurus (cattle) | CD4 | NP_001096695.1 |
Pan troglodytes (chimpanzee) | CD4 | NP_001009043.1 |
CD4 | NP_001036127.1 | |
Canis lupus familiaris (dog) | CD4 | NP_001003252.1 |
Homo sapiens (human) | CD4 | NP_000607.1 |
Mus musculus (house mouse) | Cd4 | NP_038516.1 |
Gallus gallus (chicken) | CD4 | NP_989980.1 |
Increased numbers of FoxP3-expressing CD4+ CD25+ regulatory T cells in peripheral blood from dogs with atopic dermatitis and its correlation with disease severity.
Hauck V, H?gli P, Meli ML, Rostaher A, Fischer N, Hofmann-Lehmann R, Favrot C
Veterinary dermatology27(1)26-e9(2016 Feb)
The level of CD4 surface protein influences T cell selection in the thymus.
Frank GD, Parnes JR
Journal of immunology (Baltimore, Md. : 1950)160(2)634-42(1998 Jan)
Isolation and expression of cDNA encoding the canine CD4 and CD8 alpha antigens.
Gorman SD, Frewin MR, Cobbold SP, Waldmann H
Tissue antigens43(3)184-8(1994 Mar)
Primary structure of the canine CD4 antigen.
Milde KF, Conner GE, Mintz DH, Alejandro R
Biochimica et biophysica acta1172(3)315-8(1993 Mar)
Signal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tail.
Seong RH, Chamberlain JW, Parnes JR
Nature356(6371)718-20(1992 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data suggest that in dogs, as in humans, CD4(+) CD25(+) FoxP3(+) Tregs may contribute to the pathogenesis of canine atopic dermatitis as indicated by an association between Treg frequency and disease severity
Title: Increased numbers of FoxP3-expressing CD4+ CD25+ regulatory T cells in peripheral blood from dogs with atopic dermatitis and its correlation with disease severity.
The following CD4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CD4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00019 | |
Clone ID Related Accession (Same CDS sequence) | NM_001003252.1 | |
Accession Version | NM_001003252.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1392bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Canis lupus familiaris(dog) | |
Product | T-cell surface glycoprotein CD4 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L06130.1. On Jan 12, 2005 this sequence version replaced XM_534906.1. ##Evidence-Data-START## Transcript exon combination :: L06130.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAATCAAG AAGCGGCTTT TAGGCACCTG CTCCTGATGC TGCAATTGGT GATGCTCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001003252.1 |
CDS | 159..1550 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001003252.1 |
1 | ATGAATCAAG AAGCGGCTTT TAGGCACCTG CTCCTGATGC TGCAATTGGT GATGCTCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Increased numbers of FoxP3-expressing CD4+ CD25+ regulatory T cells in peripheral blood from dogs with atopic dermatitis and its correlation with disease severity. |
The level of CD4 surface protein influences T cell selection in the thymus. |
Isolation and expression of cDNA encoding the canine CD4 and CD8 alpha antigens. |
Primary structure of the canine CD4 antigen. |
Signal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tail. |