Gene Symbol | GP1BA |
Entrez Gene ID | 403638 |
Full Name | glycoprotein Ib platelet alpha subunit |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » GP1BA cDNA ORF clone
Gene Symbol | GP1BA |
Entrez Gene ID | 403638 |
Full Name | glycoprotein Ib platelet alpha subunit |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001003083.1 | NP_001003083.1 | platelet glycoprotein Ib alpha chain precursor |
Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor.
Shen Y, Cranmer SL, Aprico A, Whisstock JC, Jackson SP, Berndt MC, Andrews RK
The Journal of biological chemistry281(36)26419-23(2006 Sep)
Molecular modeling of the seven tandem leucine-rich repeats within the ligand-binding region of platelet glycoprotein Ib alpha.
Whisstock JC, Shen Y, L?pez JA, Andrews RK, Berndt MC
Thrombosis and haemostasis87(2)329-33(2002 Feb)
Cloning and expression of canine glycoprotein Ibalpha.
Kenny D, Morateck PA, Fahs SA, Warltier DC, Montgomery RR
Thrombosis and haemostasis82(4)1327-33(1999 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data demonstrate that LRR2-4, encompassing a pronounced negative charge patch on human glycoprotein (GP)Ibalpha, is essential for GPIbalpha.von Willebrand factor-dependent adhesion as hydrodynamic shear increases.
Title: Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor.
The following GP1BA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GP1BA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00180 | |
Clone ID Related Accession (Same CDS sequence) | NM_001003083.1 | |
Accession Version | NM_001003083.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2034bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-15 | |
Organism | Canis lupus familiaris(dog) | |
Product | platelet glycoprotein Ib alpha chain precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U19489.1. ##Evidence-Data-START## Transcript exon combination :: U19489.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGCATCTGC TCCTGTGGTT GCTTCTGCTG GCCCGCCTCT GCCGCCCTGA GTTCATCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001003083.1 |
CDS | 52..2085 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001003083.1 |
1 | ATGCATCTGC TCCTGTGGTT GCTTCTGCTG GCCCGCCTCT GCCGCCCTGA GTTCATCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor. |
Molecular modeling of the seven tandem leucine-rich repeats within the ligand-binding region of platelet glycoprotein Ib alpha. |
Cloning and expression of canine glycoprotein Ibalpha. |