Gene Symbol | TIMP2 |
Entrez Gene ID | 403633 |
Full Name | TIMP metallopeptidase inhibitor 2 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » TIMP2 cDNA ORF clone
Gene Symbol | TIMP2 |
Entrez Gene ID | 403633 |
Full Name | TIMP metallopeptidase inhibitor 2 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001003082.1 | NP_001003082.1 | metalloproteinase inhibitor 2 precursor |
Homo sapiens (human) | TIMP2 | NP_003246.1 |
Bos taurus (cattle) | TIMP2 | NP_776897.2 |
Pan troglodytes (chimpanzee) | TIMP2 | XP_001146829.2 |
TIMP2 | XP_001106657.2 | |
Gallus gallus (chicken) | TIMP2 | NP_989629.1 |
Danio rerio (zebrafish) | timp2a | NP_878294.1 |
Xenopus tropicalis (tropical clawed frog) | timp2 | NP_001015760.1 |
Canis lupus familiaris (dog) | TIMP2 | NP_001003082.1 |
Mus musculus (house mouse) | Timp2 | NP_035724.2 |
Rattus norvegicus (Norway rat) | Timp2 | NP_068824.1 |
Cryoplasty for Canine Iliac Artery Stenosis and its Impact on Expression of TIMP-2 and MMP-2.
Wu Z, Zang S, Liu W, Jiang N, Yang W
Vascular and endovascular surgery49(5-6)135-41(2015 Jul-Aug)
Dynamic alterations of connexin43, matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 during ventricular fibrillation in canine.
Wang J, Li JS, Liu HZ, Yi SL, Su GY, Zhang Y, Zhong JQ
Molecular and cellular biochemistry391(1-2)259-66(2014 Jun)
Expression of matrix metalloproteinases, tissue inhibitors of metalloproteinases and vascular endothelial growth factor in canine mast cell tumours.
Giantin M, Aresu L, Benali S, Aric? A, Morello EM, Martano M, Vascellari M, Castagnaro M, Lopparelli RM, Zancanella V, Granato A, Mutinelli F, Dacasto M
Journal of comparative pathology147(4)419-29(2012 Nov)
Soluble factors-mediated immunomodulatory effects of canine adipose tissue-derived mesenchymal stem cells.
Kang JW, Kang KS, Koo HC, Park JR, Choi EW, Park YH
Stem cells and development17(4)681-93(2008 Aug)
The cloning and expression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase 2 in normal canine lymph nodes and in canine lymphoma.
Newman RG, Kitchell BE, Wallig MA, Paria B
Research in veterinary science84(2)206-14(2008 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Suggest cryoplasty increases the expression of TIMP-2 and decreases the expression of MMP-2, thereby inhibiting vascular hyperplasia and collagen fibers synthesis in the stenotic vessels.
Title: Cryoplasty for Canine Iliac Artery Stenosis and its Impact on Expression of TIMP-2 and MMP-2.
the alteration of Cx43 and/or phosphorylated Cx43 levels and the imbalance of MMP-2 and TIMP-2 may contribute to the initiation and/or persistence of ventricular fibrillation.
Title: Dynamic alterations of connexin43, matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 during ventricular fibrillation in canine.
This study demonstrates that MMP-9, TIMP-2 and VEGF-A expression is related to histological grade in canine mast cell tumors.
Title: Expression of matrix metalloproteinases, tissue inhibitors of metalloproteinases and vascular endothelial growth factor in canine mast cell tumours.
Adipose tissue-derived mesenchymal stem cells expressed the mRNA of transforming growth factor beta (TGF-beta), IL-6, IL-8, CCL2, CCL5, VEGF,HGF, tissue inhibitor metalloproteinase-1/2, and cyclooxygenase-2 but not that of IL-10.
Title: Soluble factors-mediated immunomodulatory effects of canine adipose tissue-derived mesenchymal stem cells.
The cloning of matrix metallopeptidase 2 (MMP2)and its expression with tissue inhibitor of matrix metalloproteinase 2 (TIMP2) in canine lymph nodes and lymphomas are reported.
Title: The cloning and expression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase 2 in normal canine lymph nodes and in canine lymphoma.
The following TIMP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TIMP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00153 | |
Clone ID Related Accession (Same CDS sequence) | NM_001003082.1 | |
Accession Version | NM_001003082.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 663bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-23 | |
Organism | Canis lupus familiaris(dog) | |
Product | metalloproteinase inhibitor 2 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF112115.1. ##Evidence-Data-START## Transcript exon combination :: AF112115.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCGCCG CGGCCCGCAG CCTGCGCCTG GCGCTCGGCC TCCTGCTGCT GGCGACGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001003082.1 |
CDS | 3..665 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001003082.1 |
1 | ATGGGCGCCG CGGCCCGCAG CCTGCGCCTG GCGCTCGGCC TCCTGCTGCT GGCGACGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cryoplasty for Canine Iliac Artery Stenosis and its Impact on Expression of TIMP-2 and MMP-2. |
Dynamic alterations of connexin43, matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 during ventricular fibrillation in canine. |
Expression of matrix metalloproteinases, tissue inhibitors of metalloproteinases and vascular endothelial growth factor in canine mast cell tumours. |
Soluble factors-mediated immunomodulatory effects of canine adipose tissue-derived mesenchymal stem cells. |
The cloning and expression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase 2 in normal canine lymph nodes and in canine lymphoma. |