Gene Symbol | FTH1 |
Entrez Gene ID | 403631 |
Full Name | ferritin, heavy polypeptide 1 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » FTH1 cDNA ORF clone
Gene Symbol | FTH1 |
Entrez Gene ID | 403631 |
Full Name | ferritin, heavy polypeptide 1 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001003080.1 | NP_001003080.1 | ferritin heavy chain |
Hydrogen peroxide and extracellular signal-related kinase 1/2 pathway regulate ferritin levels in retinal pigmented and lens epithelial cells.
Lall MM, Harned J, McGahan MC
Molecular vision192106-12(2013)
Altered ferritin subunit composition: change in iron metabolism in lens epithelial cells and downstream effects on glutathione levels and VEGF secretion.
Harned J, Ferrell J, Lall MM, Fleisher LN, Nagar S, Goralska M, McGahan MC
Investigative ophthalmology & visual science51(9)4437-46(2010 Sep)
Sequence analysis of canine and equine ferritin H and L subunit cDNAs.
Orino K, Miura T, Muto S, Watanabe K
DNA sequence : the journal of DNA sequencing and mapping16(1)58-64(2005 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
This is the first study to demonstrate that hydrogen peroxide and an inhibitor of ERK1/2 activation can increase the levels of the iron storage protein, ferritin.
Title: Hydrogen peroxide and extracellular signal-related kinase 1/2 pathway regulate ferritin levels in retinal pigmented and lens epithelial cells.
Most of the effects of altering the ferritin H:L ratio with the specific siRNAs were due to changes in the availability of iron in a labile pool
Title: Altered ferritin subunit composition: change in iron metabolism in lens epithelial cells and downstream effects on glutathione levels and VEGF secretion.
The following FTH1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FTH1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00255 | |
Clone ID Related Accession (Same CDS sequence) | NM_001003080.1 | |
Accession Version | NM_001003080.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-12-07 | |
Organism | Canis lupus familiaris(dog) | |
Product | ferritin heavy chain | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF285177.1. ##Evidence-Data-START## Transcript exon combination :: AF285177.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGACGACCG CGTCCCCCTC GCAGGTGCGC CAGAACTACC ACCAGGACTC CGAGGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001003080.1 |
CDS | 182..733 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001003080.1 |
1 | ATGACGACCG CGTCCCCCTC GCAGGTGCGC CAGAACTACC ACCAGGACTC CGAGGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Hydrogen peroxide and extracellular signal-related kinase 1/2 pathway regulate ferritin levels in retinal pigmented and lens epithelial cells. |
Altered ferritin subunit composition: change in iron metabolism in lens epithelial cells and downstream effects on glutathione levels and VEGF secretion. |
Sequence analysis of canine and equine ferritin H and L subunit cDNAs. |