KL cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	KL
Entrez Gene ID	100685604
Full Name	klotho
General protein information	Preferred Names klotho Names klotho
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
XM_003433309.2	XP_003433357.1	klotho

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	KL	XP_522655.2
	LOC714042	XP_001101127.1
Homo sapiens (human)	KL	NP_004786.2
Canis lupus familiaris (dog)	KL	XP_003433357.1
Bos taurus (cattle)	KL	NP_001178124.1
Mus musculus (house mouse)	Kl	NP_038851.2
Danio rerio (zebrafish)	kl	XP_690797.4
Rattus norvegicus (Norway rat)	Kl	NP_112626.1
Gallus gallus (chicken)	KL	XP_004938814.1
Xenopus tropicalis (tropical clawed frog)	kl	XP_002934067.1

Gene Ontology

The following KL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe25499	XM_003433309.2 Latest version!	Canis lupus familiaris klotho (KL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$510.30 $729.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KL ( XM_003433309.2 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_003433357.1 Canis lupus familiaris klotho (KL), mRNA.

Price & Availability↑

CloneID	OCe25499
Clone ID Related Accession (Same CDS sequence)	XM_003433309.2
Accession Version	XM_003433309.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2595bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	klotho
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006607.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2013 this sequence version replaced XM_003433309.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases ##RefSeq-Attributes-END##

ATGGCCACCT GCATTTTACA GATGAGATTC CTAAGGCTGG GGAAGATACT GTTCCACTCC 
AGCCCACAAA GCACAGGTGG CAGTGGTGGG ACCCGGGGAC CTCGAGCTCC GGCACAGCTG 
CGAACGCAGC GTGGCACAGA TAAGTTAGTT GCTAAGTCAG AGCTCAAGGC TAAAACGGCC 
CACCGCGCGC TGGCCGACCA CTTCAGGGAC TACGCCGAGC TCTGCTTCCG CCACTTCTGC 
GGCCAGGTCA AGTACTGGAT CACCATCGAC AACCCCTACG TGGTGGCCTG GCACGGCTAC 
GCCACCGGGC GCCTGGCCCC CGGCGTCCGG GGCAGCCCGC GGCTCGGGTA CCTGGTGGCG 
CACAACCTCC TCCTGGCTCA CGCCAAAATC TGGCATCTCT ACAATACTTC TTTCCGCCCA 
ACTCAGGGAG GCCAGGTATC CATTGCCCTA AGCTCCCACT GGATCAATCC TCGAAGAATG 
ACCGACCATA GCATCAAAGA ATGTCAAAAA TCTCTTGACT TTGTACTAGG CTGGTTTGCC 
AAGCCCATAT TTATTGATGG TGACTATCCT GAGAGCATGA AGAATAACCT GTCATCTCTT 
CTGCCTGTTT TTACTGAATC TGAGAAAAAG TTCATCAAGG GAACAGCTGA CTTTTTTGCT 
CTTTCTTTTG GACCAACTTT GAGTTTTCAA CTCTTGGACC CTCATATGAA GTTCCACCAA 
TTAGAATCTC CCAGCCTGAG GCAACTCCTT TCTTGGATTG ACCTTGAATA TAACCACCCT 
CAAATATTTA TTGTGGAAAA TGGCTGGTTT GTCTCAGGGA CCACCAAGAG AGATGATGCC 
AAATATATGT ATTACCTCAA AAAATTCATA ATGGAAACCT TAAAAGCCAT CAGGCTGGAT 
GGGGTGGATG TCATAGGATA CACAGCGTGG TCCCTTATGG ATGGCTTCGA GTGGCACAGA 
GGCTACAGCA TCAGACGTGG ACTCTTCTAC GTGGACTTTC TAAGCCAGGA TAAGAAACTG 
TTGCCAAAGT CTTCAGCCTT GTTCTACCAA AAGCTGATAG AGAAAAATGG CTTCCCTCCT 
TTACCTGAAA ATCAGCCCCT AGAAGGGACA TTTCCCTGTG ACTTTGCTTG GGGAATTGTT 
GACAACTACA TTCAAGTGGA CACCACTCTG TCTCAGTTTA CCGACCCGAA CGTTTACCTG 
TGGGACGTCC ATCACAGCAA GAGGCTGATT AAGGTGGACG GGCTGCGGGC CAAGAAGAGG 
AAGCCCTACT GCGTGGACTT TGCCGCCATC GGGCCCCAGG TGGCCCTGCT GCAGGAGATG 
CACGTCTCGC ATTTTCACTT CTCGCTGGAC TGGGCCCTGC TCCTGCCGCT GGGCAACCAG 
TCCCGGGTGA ACCACGCGGC CCTGCACTAC TACGGCTGCG TGGCCAGCGA GCTCCTGCGC 
GCCAACATCA CCCCGGTGGT GGCGCTCTGG CGCCCCGCCG CCGCGCACCA GGGCCTGCCG 
GGGCCGCTGG CCCAGCGCGG CGCCTGGGAG AACCCGCGCA CCGCCCTGGC GTTCGCCGAG 
TACGCGCGCC TGTGCTTCCG CGCCCTGGGC CGCCACGTCA AGGTGTGGAT CACGCTGCGC 
GAGCCGCCCA CGCGGAACCT GACGCTCCGC GCCGGGCACA ACCTGCTGCG GGCGCACGCG 
CTGGCCTGGC GCGTGTACGA CGAGCAGTTC CGGGGCTCGC AGCAGGGGAA GGTGTCCATC 
GCCCTGCAGG CCGACTGGGT GGAGCCCGCC TGCCCCTCCT CCCAGAAGGA CCGCGAAGTG 
GCCGAGAGGG TTCTGGAGTT CGACGTCGGC TGGCTGGCCG AGCCCATCTT CGGCTCCGGG 
GACTACCCGC GGCTGATGCG CGACTGGCTC ACCCGGAGAG ACCATTCCCT CCTGCCCTAT 
TTCACTGACG AAGAGAAGAG GCTAATCCGG GGTTCCTTTG ACTTCCTGGC CTTGAGCCAT 
TACACCACCA TCCTCGTGGA CTGGGAAAAG GAAGACCCAG TCAAATACAA TGATTACCTG 
GAAGTGCAGG AGATGACCGA CATCACCTGG CTCAACTCCC CCAGTCAGGT GGCCGTAGTG 
CCCTGGGGCC TGCGCAAAGT GCTCAACTGG CTCAAGTTCA AGTACGGAGA CCTCCCCATG 
TATATCGTAT CCAACGGCAT AGATGACGAT CCGCGGGCAG CCCAGGACTC GTTGAGGGTG 
TATTACATGC AGAACTATGT AAATGAAGCT CTGAAAGCCT ACGTATTGGA TGGTATCAAT 
CTTTGTGGAT ACTTTGCCTA CTCATTTAAT GATCGCACAG CTCCGAAGTT TGGCCTCTAT 
CATTATGCTG CAAACCAGTT TGAGCCCAAA CCGTCGGTGA AGCATTACAG GAAAATTATT 
GACAACAATG GCTTCCCAGG CCCTGAAACT TTGGGGCGGT TTTGTCCAGA GGAATTCACC 
CTGTGCACCG AATGCAGCTT TTTTCACACC CGAAAGTCTT TACTGGCTTT CATAGCTTTC 
CTACTTTTTG CTTTTATTAT TTCTCTTTCT CTGATTTTCT ACTACTCTAG GAAAGGCAGA 
AGAAGTTATA AATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_003433357.1
CDS	1..2595
Translation	MATCILQMRFLRLGKILFHSSPQSTGGSGGTRGPRAPAQLRTQRGTDKLVAKSELKAKTAHRALADHFRDYAELCFRHFCGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSPRLGYLVAHNLLLAHAKIWHLYNTSFRPTQGGQVSIALSSHWINPRRMTDHSIKECQKSLDFVLGWFAKPIFIDGDYPESMKNNLSSLLPVFTESEKKFIKGTADFFALSFGPTLSFQLLDPHMKFHQLESPSLRQLLSWIDLEYNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKKLLPKSSALFYQKLIEKNGFPPLPENQPLEGTFPCDFAWGIVDNYIQVDTTLSQFTDPNVYLWDVHHSKRLIKVDGLRAKKRKPYCVDFAAIGPQVALLQEMHVSHFHFSLDWALLLPLGNQSRVNHAALHYYGCVASELLRANITPVVALWRPAAAHQGLPGPLAQRGAWENPRTALAFAEYARLCFRALGRHVKVWITLREPPTRNLTLRAGHNLLRAHALAWRVYDEQFRGSQQGKVSIALQADWVEPACPSSQKDREVAERVLEFDVGWLAEPIFGSGDYPRLMRDWLTRRDHSLLPYFTDEEKRLIRGSFDFLALSHYTTILVDWEKEDPVKYNDYLEVQEMTDITWLNSPSQVAVVPWGLRKVLNWLKFKYGDLPMYIVSNGIDDDPRAAQDSLRVYYMQNYVNEALKAYVLDGINLCGYFAYSFNDRTAPKFGLYHYAANQFEPKPSVKHYRKIIDNNGFPGPETLGRFCPEEFTLCTECSFFHTRKSLLAFIAFLLFAFIISLSLIFYYSRKGRRSYK

Target ORF information:

RefSeq Version	XM_003433309.2
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris klotho (KL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_003433309.2

ORF Insert Sequence:

ATGGCCACCT GCATTTTACA GATGAGATTC CTAAGGCTGG GGAAGATACT GTTCCACTCC 
AGCCCACAAA GCACAGGTGG CAGTGGTGGG ACCCGGGGAC CTCGAGCTCC GGCACAGCTG 
CGAACGCAGC GTGGCACAGA TAAGTTAGTT GCTAAGTCAG AGCTCAAGGC TAAAACGGCC 
CACCGCGCGC TGGCCGACCA CTTCAGGGAC TACGCCGAGC TCTGCTTCCG CCACTTCTGC 
GGCCAGGTCA AGTACTGGAT CACCATCGAC AACCCCTACG TGGTGGCCTG GCACGGCTAC 
GCCACCGGGC GCCTGGCCCC CGGCGTCCGG GGCAGCCCGC GGCTCGGGTA CCTGGTGGCG 
CACAACCTCC TCCTGGCTCA CGCCAAAATC TGGCATCTCT ACAATACTTC TTTCCGCCCA 
ACTCAGGGAG GCCAGGTATC CATTGCCCTA AGCTCCCACT GGATCAATCC TCGAAGAATG 
ACCGACCATA GCATCAAAGA ATGTCAAAAA TCTCTTGACT TTGTACTAGG CTGGTTTGCC 
AAGCCCATAT TTATTGATGG TGACTATCCT GAGAGCATGA AGAATAACCT GTCATCTCTT 
CTGCCTGTTT TTACTGAATC TGAGAAAAAG TTCATCAAGG GAACAGCTGA CTTTTTTGCT 
CTTTCTTTTG GACCAACTTT GAGTTTTCAA CTCTTGGACC CTCATATGAA GTTCCACCAA 
TTAGAATCTC CCAGCCTGAG GCAACTCCTT TCTTGGATTG ACCTTGAATA TAACCACCCT 
CAAATATTTA TTGTGGAAAA TGGCTGGTTT GTCTCAGGGA CCACCAAGAG AGATGATGCC 
AAATATATGT ATTACCTCAA AAAATTCATA ATGGAAACCT TAAAAGCCAT CAGGCTGGAT 
GGGGTGGATG TCATAGGATA CACAGCGTGG TCCCTTATGG ATGGCTTCGA GTGGCACAGA 
GGCTACAGCA TCAGACGTGG ACTCTTCTAC GTGGACTTTC TAAGCCAGGA TAAGAAACTG 
TTGCCAAAGT CTTCAGCCTT GTTCTACCAA AAGCTGATAG AGAAAAATGG CTTCCCTCCT 
TTACCTGAAA ATCAGCCCCT AGAAGGGACA TTTCCCTGTG ACTTTGCTTG GGGAATTGTT 
GACAACTACA TTCAAGTGGA CACCACTCTG TCTCAGTTTA CCGACCCGAA CGTTTACCTG 
TGGGACGTCC ATCACAGCAA GAGGCTGATT AAGGTGGACG GGCTGCGGGC CAAGAAGAGG 
AAGCCCTACT GCGTGGACTT TGCCGCCATC GGGCCCCAGG TGGCCCTGCT GCAGGAGATG 
CACGTCTCGC ATTTTCACTT CTCGCTGGAC TGGGCCCTGC TCCTGCCGCT GGGCAACCAG 
TCCCGGGTGA ACCACGCGGC CCTGCACTAC TACGGCTGCG TGGCCAGCGA GCTCCTGCGC 
GCCAACATCA CCCCGGTGGT GGCGCTCTGG CGCCCCGCCG CCGCGCACCA GGGCCTGCCG 
GGGCCGCTGG CCCAGCGCGG CGCCTGGGAG AACCCGCGCA CCGCCCTGGC GTTCGCCGAG 
TACGCGCGCC TGTGCTTCCG CGCCCTGGGC CGCCACGTCA AGGTGTGGAT CACGCTGCGC 
GAGCCGCCCA CGCGGAACCT GACGCTCCGC GCCGGGCACA ACCTGCTGCG GGCGCACGCG 
CTGGCCTGGC GCGTGTACGA CGAGCAGTTC CGGGGCTCGC AGCAGGGGAA GGTGTCCATC 
GCCCTGCAGG CCGACTGGGT GGAGCCCGCC TGCCCCTCCT CCCAGAAGGA CCGCGAAGTG 
GCCGAGAGGG TTCTGGAGTT CGACGTCGGC TGGCTGGCCG AGCCCATCTT CGGCTCCGGG 
GACTACCCGC GGCTGATGCG CGACTGGCTC ACCCGGAGAG ACCATTCCCT CCTGCCCTAT 
TTCACTGACG AAGAGAAGAG GCTAATCCGG GGTTCCTTTG ACTTCCTGGC CTTGAGCCAT 
TACACCACCA TCCTCGTGGA CTGGGAAAAG GAAGACCCAG TCAAATACAA TGATTACCTG 
GAAGTGCAGG AGATGACCGA CATCACCTGG CTCAACTCCC CCAGTCAGGT GGCCGTAGTG 
CCCTGGGGCC TGCGCAAAGT GCTCAACTGG CTCAAGTTCA AGTACGGAGA CCTCCCCATG 
TATATCGTAT CCAACGGCAT AGATGACGAT CCGCGGGCAG CCCAGGACTC GTTGAGGGTG 
TATTACATGC AGAACTATGT AAATGAAGCT CTGAAAGCCT ACGTATTGGA TGGTATCAAT 
CTTTGTGGAT ACTTTGCCTA CTCATTTAAT GATCGCACAG CTCCGAAGTT TGGCCTCTAT 
CATTATGCTG CAAACCAGTT TGAGCCCAAA CCGTCGGTGA AGCATTACAG GAAAATTATT 
GACAACAATG GCTTCCCAGG CCCTGAAACT TTGGGGCGGT TTTGTCCAGA GGAATTCACC 
CTGTGCACCG AATGCAGCTT TTTTCACACC CGAAAGTCTT TACTGGCTTT CATAGCTTTC 
CTACTTTTTG CTTTTATTAT TTCTCTTTCT CTGATTTTCT ACTACTCTAG GAAAGGCAGA 
AGAAGTTATA AATAG