rab-10 cDNA ORF clone, Caenorhabditis elegans

Gene
Clones
gRNAs

Summary

Gene Symbol	rab-10
Entrez Gene ID	266836
Full Name	Ras-related protein Rab-10
Gene Type	protein-coding
Organism	Caenorhabditis elegans

mRNA and Protein(s)

mRNA	Protein	Name
NM_059456.4	NP_491857.1	Ras-related protein Rab-10
NM_059456.5	NP_491857.1	Ras-related protein Rab-10

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	RAB10	XP_525714.2
Bos taurus (cattle)	RAB10	NP_001094758.1
Caenorhabditis elegans (roundworm)	rab-10	NP_491857.1
Mus musculus (house mouse)	Rab10	NP_057885.1
Rattus norvegicus (Norway rat)	Rab10	NP_059055.2
Gallus gallus (chicken)	RAB10	NP_001026268.1
Arabidopsis thaliana (thale cress)	RAB8C	NP_195972.1
Arabidopsis thaliana (thale cress)	RABE1e	NP_187601.1
Homo sapiens (human)	RAB10	NP_057215.3
Danio rerio (zebrafish)	rab10	NP_001002566.1
Canis lupus familiaris (dog)	RAB10	NP_001003277.2
Drosophila melanogaster (fruit fly)	Rab10	NP_523419.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000671	XP_311197.3

Gene Ontology
Bibliography

Related articles in PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.

Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

dendritic branch distribution depends on the balance between the molecular motors UNC-116 and dynein, and we propose that RAB-10 regulates dendrite morphology by balancing the activity of these motors to the transmembrane receptor DMA-1.
Title: RAB-10 Regulates Dendritic Branching by Balancing Dendritic Transport.

the loss of TBC-2 or AMPH-1 leads to abnormally high spatial overlap of RAB-5 and RAB-10. RAB-10 and AMPH-1 mediated down-regulation of RAB-5 is an important step in recycling, required for cargo exit from early endosomes
Title: Basolateral Endocytic Recycling Requires RAB-10 and AMPH-1 Mediated Recruitment of RAB-5 GAP TBC-2 to Endosomes.

Together these results suggest a crucial role for the Rab10 GTPase and the exocyst complex in controlling membrane transport from the secretory and/or endosomal compartments that is required for dendritic growth
Title: RAB-10-Dependent Membrane Transport Is Required for Dendrite Arborization.

SEC-10 coordinates with RAB-10 and microtubules to form the endosomal tubular network for efficient recycling of particular clathrin-independent endocytic cargoes.
Title: SEC-10 and RAB-10 coordinate basolateral recycling of clathrin-independent cargo through endosomal tubules in Caenorhabditis elegans.

RAB-5 and RAB-10 cooperate to locally exclude each other at an essential stage during DCV sorting.
Title: RAB-5 and RAB-10 cooperate to regulate neuropeptide release in Caenorhabditis elegans.

The following rab-10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the rab-10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCa336951	NM_059456.5 Latest version!	Caenorhabditis elegans Ras-related protein Rab-10 (rab-10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OCa336951	NM_059456.4	Caenorhabditis elegans Ras-related protein Rab-10 (rab-10), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

rab-10 ( NM_059456.4 ) cDNA ORF clone, Caenorhabditis elegans -> NP_491857.1 Caenorhabditis elegans Ras-related protein Rab-10 (rab-10), partial mRNA.

Price & Availability↑

CloneID	OCa336951
Clone ID Related Accession (Same CDS sequence)	NM_059456.4 , NM_059456.5
Accession Version	NM_059456.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-08
Organism	Caenorhabditis elegans
Product	Ras-related protein Rab-10
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_059456.3. COMPLETENESS: incomplete on both ends.

ATGGCTCGCC GACCGTATGA CATGCTCTTC AAATTGCTGC TAATAGGCGA CTCAGGAGTT 
GGAAAAACTT GCATTCTGTA CAGATTTTCG GATGATGCCT TTAACACCAC ATTCATCTCA 
ACTATTGGAA TCGACTTCAA AATTAAAACT ATCGAATTAA AAGGAAAAAA GATTAAATTA 
CAAATCTGGG ACACAGCTGG ACAAGAACGA TTCCACACAA TCACAACATC ATATTACCGC 
GGAGCAATGG GAATTATGCT GGTTTACGAT ATCACAAATG CGAAAAGTTT TGACAATATT 
GCAAAGTGGT TGCGCAATAT TGACGAACAT GCATCGGAAG ATGTTGTTAA AATGATATTG 
GGAAATAAAT GTGATATGAG TGATAGACGA GTTGTGAGCA GAGAACGAGG AGAGAAGATC 
GCACAAGATC ATGGTATTAG CTTCCACGAG ACTTCAGCTA AATTGAATGT TCACGTCGAT 
ACAGCGTTTT ACGATTTAGC AGAAGCAATT CTGGCTAAGA TGCCTGATTC CACTGACGAG 
CAATCCCGCG ATACGGTGAA TCCAGTGCAA CCACAGAGGC AGAGTAGCAG TGGAGGATGC 
TGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_491857.1
CDS	1..606
Translation	MARRPYDMLFKLLLIGDSGVGKTCILYRFSDDAFNTTFISTIGIDFKIKTIELKGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNAKSFDNIAKWLRNIDEHASEDVVKMILGNKCDMSDRRVVSRERGEKIAQDHGISFHETSAKLNVHVDTAFYDLAEAILAKMPDSTDEQSRDTVNPVQPQRQSSSGGCC

Target ORF information:

RefSeq Version	NM_059456.4
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans Ras-related protein Rab-10 (rab-10), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_059456.4

ORF Insert Sequence:

ATGGCTCGCC GACCGTATGA CATGCTCTTC AAATTGCTGC TAATAGGCGA CTCAGGAGTT 
GGAAAAACTT GCATTCTGTA CAGATTTTCG GATGATGCCT TTAACACCAC ATTCATCTCA 
ACTATTGGAA TCGACTTCAA AATTAAAACT ATCGAATTAA AAGGAAAAAA GATTAAATTA 
CAAATCTGGG ACACAGCTGG ACAAGAACGA TTCCACACAA TCACAACATC ATATTACCGC 
GGAGCAATGG GAATTATGCT GGTTTACGAT ATCACAAATG CGAAAAGTTT TGACAATATT 
GCAAAGTGGT TGCGCAATAT TGACGAACAT GCATCGGAAG ATGTTGTTAA AATGATATTG 
GGAAATAAAT GTGATATGAG TGATAGACGA GTTGTGAGCA GAGAACGAGG AGAGAAGATC 
GCACAAGATC ATGGTATTAG CTTCCACGAG ACTTCAGCTA AATTGAATGT TCACGTCGAT 
ACAGCGTTTT ACGATTTAGC AGAAGCAATT CTGGCTAAGA TGCCTGATTC CACTGACGAG 
CAATCCCGCG ATACGGTGAA TCCAGTGCAA CCACAGAGGC AGAGTAGCAG TGGAGGATGC 
TGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

rab-10 ( NM_059456.5 ) cDNA ORF clone, Caenorhabditis elegans -> NP_491857.1 Caenorhabditis elegans Ras-related protein Rab-10 (rab-10), mRNA.

Price & Availability↑

CloneID	OCa336951
Clone ID Related Accession (Same CDS sequence)	NM_059456.4 , NM_059456.5
Accession Version	NM_059456.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-17
Organism	Caenorhabditis elegans
Product	Ras-related protein Rab-10
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_059456.4.

ATGGCTCGCC GACCGTATGA CATGCTCTTC AAATTGCTGC TAATAGGCGA CTCAGGAGTT 
GGAAAAACTT GCATTCTGTA CAGATTTTCG GATGATGCCT TTAACACCAC ATTCATCTCA 
ACTATTGGAA TCGACTTCAA AATTAAAACT ATCGAATTAA AAGGAAAAAA GATTAAATTA 
CAAATCTGGG ACACAGCTGG ACAAGAACGA TTCCACACAA TCACAACATC ATATTACCGC 
GGAGCAATGG GAATTATGCT GGTTTACGAT ATCACAAATG CGAAAAGTTT TGACAATATT 
GCAAAGTGGT TGCGCAATAT TGACGAACAT GCATCGGAAG ATGTTGTTAA AATGATATTG 
GGAAATAAAT GTGATATGAG TGATAGACGA GTTGTGAGCA GAGAACGAGG AGAGAAGATC 
GCACAAGATC ATGGTATTAG CTTCCACGAG ACTTCAGCTA AATTGAATGT TCACGTCGAT 
ACAGCGTTTT ACGATTTAGC AGAAGCAATT CTGGCTAAGA TGCCTGATTC CACTGACGAG 
CAATCCCGCG ATACGGTGAA TCCAGTGCAA CCACAGAGGC AGAGTAGCAG TGGAGGATGC 
TGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_491857.1
CDS	8..613
Translation	MARRPYDMLFKLLLIGDSGVGKTCILYRFSDDAFNTTFISTIGIDFKIKTIELKGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNAKSFDNIAKWLRNIDEHASEDVVKMILGNKCDMSDRRVVSRERGEKIAQDHGISFHETSAKLNVHVDTAFYDLAEAILAKMPDSTDEQSRDTVNPVQPQRQSSSGGCC

Target ORF information:

RefSeq Version	NM_059456.5
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans Ras-related protein Rab-10 (rab-10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_059456.5

ORF Insert Sequence:

ATGGCTCGCC GACCGTATGA CATGCTCTTC AAATTGCTGC TAATAGGCGA CTCAGGAGTT 
GGAAAAACTT GCATTCTGTA CAGATTTTCG GATGATGCCT TTAACACCAC ATTCATCTCA 
ACTATTGGAA TCGACTTCAA AATTAAAACT ATCGAATTAA AAGGAAAAAA GATTAAATTA 
CAAATCTGGG ACACAGCTGG ACAAGAACGA TTCCACACAA TCACAACATC ATATTACCGC 
GGAGCAATGG GAATTATGCT GGTTTACGAT ATCACAAATG CGAAAAGTTT TGACAATATT 
GCAAAGTGGT TGCGCAATAT TGACGAACAT GCATCGGAAG ATGTTGTTAA AATGATATTG 
GGAAATAAAT GTGATATGAG TGATAGACGA GTTGTGAGCA GAGAACGAGG AGAGAAGATC 
GCACAAGATC ATGGTATTAG CTTCCACGAG ACTTCAGCTA AATTGAATGT TCACGTCGAT 
ACAGCGTTTT ACGATTTAGC AGAAGCAATT CTGGCTAAGA TGCCTGATTC CACTGACGAG 
CAATCCCGCG ATACGGTGAA TCCAGTGCAA CCACAGAGGC AGAGTAGCAG TGGAGGATGC 
TGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

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rab-10 cDNA ORF clone, Caenorhabditis elegans

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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