Gene Symbol | daf-28 |
Entrez Gene ID | 191014 |
Full Name | hypothetical protein |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » daf-28 cDNA ORF clone
Gene Symbol | daf-28 |
Entrez Gene ID | 191014 |
Full Name | hypothetical protein |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_075439.2 | NP_507840.1 | hypothetical protein |
NM_075439.1 | NP_507840.1 | hypothetical protein |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Using functional, fluorescently-tagged protein, we find that, in animals with mutant DAF-28/IGF, the wild-type DAF-7/TGF-beta is mislocalized to and accumulates in the proximal axon of the ASI neuron. Activation of two different branches of the unfolded protein response can modulate both the developmental phenotype and DAF-7 mislocalization in DAF-28(R37C) animals, but appear to act through divergent mechanisms
Title: A Bystander Mechanism Explains the Specific Phenotype of a Broadly Expressed Misfolded Protein.
Ins-4 and daf-28 function redundantly to regulate C. elegans L1 arrest.
Title: Ins-4 and daf-28 function redundantly to regulate C. elegans L1 arrest.
DAF-8 partners with the nuclear hormone receptor NHR-69, a C. elegans ortholog of mammalian hepatocyte nuclear factor 4alpha HNF4alpha), to repress the exp-2 potassium channel gene and increase insulin secretion
Title: Repression of a potassium channel by nuclear hormone receptor and TGF-? signaling modulates insulin signaling in Caenorhabditis elegans.
conclude that mitochondrial function is required for C. elegans to secrete DAF-28/insulin when food is abundant
Title: Mitochondrial function is required for secretion of DAF-28/insulin in C. elegans.
TRX-1 modulates DAF-28 signaling by contributing to the down-regulation of daf-28 expression during dauer formation.
Title: The thioredoxin TRX-1 modulates the function of the insulin-like neuropeptide DAF-28 during dauer formation in Caenorhabditis elegans.
The following daf-28 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the daf-28 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa360380 | |
Clone ID Related Accession (Same CDS sequence) | NM_075439.2 , NM_075439.1 | |
Accession Version | NM_075439.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 294bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Caenorhabditis elegans | |
Product | hypothetical protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_075439.1. |
1 | ATGAACTGCA AGCTCATCGC CATCTTTGCC GTACTCGTCC TCTCCGTCTC GGCTCATCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_507840.1 |
CDS | 164..457 |
Translation |
Target ORF information:
Target ORF information:
|
NM_075439.2 |
1 | ATGAACTGCA AGCTCATCGC CATCTTTGCC GTACTCGTCC TCTCCGTCTC GGCTCATCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa360380 | |
Clone ID Related Accession (Same CDS sequence) | NM_075439.2 , NM_075439.1 | |
Accession Version | NM_075439.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 294bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-09 | |
Organism | Caenorhabditis elegans | |
Product | hypothetical protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). COMPLETENESS: incomplete on both ends. |
1 | ATGAACTGCA AGCTCATCGC CATCTTTGCC GTACTCGTCC TCTCCGTCTC GGCTCATCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_507840.1 |
CDS | 1..294 |
Translation |
Target ORF information:
Target ORF information:
|
NM_075439.1 |
1 | ATGAACTGCA AGCTCATCGC CATCTTTGCC GTACTCGTCC TCTCCGTCTC GGCTCATCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |