Gene Symbol | trx-1 |
Entrez Gene ID | 181863 |
Full Name | Thioredoxin-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » trx-1 cDNA ORF clone
Gene Symbol | trx-1 |
Entrez Gene ID | 181863 |
Full Name | Thioredoxin-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001026714.3 | NP_001021885.1 | Thioredoxin-1 |
NM_001026714.4 | NP_001021885.1 | Thioredoxin-1 |
NM_001026715.4 | NP_001021886.1 | Thioredoxin-1 |
NM_001026715.5 | NP_001021886.1 | Thioredoxin-1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Trx-1 regulates intestinal SKN-1 nuclear localization in a cell non-autonomous manner.
Title: TRX-1 Regulates SKN-1 Nuclear Localization Cell Non-autonomously in Caenorhabditis elegans.
Dietary restriction activates TRX-1 in ASJ neurons during aging, which in turn triggers TRX-1-dependent mechanisms to extend adult lifespan in the worm.
Title: The thioredoxin TRX-1 regulates adult lifespan extension induced by dietary restriction in Caenorhabditis elegans.
TRX-1 acts as a fluctuating neuronal signaling modulator within ASJ neurons to monitor the adjustment of neuropeptide expression, including insulin-like proteins, during dauer formation in response to adverse environmental conditions.
Title: The thioredoxin TRX-1 modulates the function of the insulin-like neuropeptide DAF-28 during dauer formation in Caenorhabditis elegans.
Suppression of the C. elegans thioredoxin orthologs trx-1 and trx-2, involved in the redox chaperone activity of exo-3, overrides the protective effect of cep-1 RNAi treatment on neuronal integrity, neuronal function, mean and maximum life span.
Title: Apurinic/apyrimidinic endonuclease 1, p53, and thioredoxin are linked in control of aging in C. elegans.
Data describe a Caenorhabditis elegans thioredoxin (TRX-1), encoded by the gene B0228.5, that is expressed in ASJ ciliated sensory neurons.
Title: Lifespan decrease in a Caenorhabditis elegans mutant lacking TRX-1, a thioredoxin expressed in ASJ sensory neurons.
The following trx-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the trx-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa338363 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026714.3 , NM_001026714.4 | |
Accession Version | NM_001026714.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 348bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Thioredoxin-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_001026714.2. COMPLETENESS: incomplete on both ends. |
1 | ATGTTGAAAC GATGCAACTT CAAAAATCAA GTAAAATATT TTCAGAGTGA CTTTGAGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021885.1 |
CDS | 1..348 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026714.3 |
1 | ATGTTGAAAC GATGCAACTT CAAAAATCAA GTAAAATATT TTCAGAGTGA CTTTGAGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa338363 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026714.3 , NM_001026714.4 | |
Accession Version | NM_001026714.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 348bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Thioredoxin-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_001026714.3. |
1 | ATGTTGAAAC GATGCAACTT CAAAAATCAA GTAAAATATT TTCAGAGTGA CTTTGAGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021885.1 |
CDS | 25..372 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026714.4 |
1 | ATGTTGAAAC GATGCAACTT CAAAAATCAA GTAAAATATT TTCAGAGTGA CTTTGAGCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa338364 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026715.4 , NM_001026715.5 | |
Accession Version | NM_001026715.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 345bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Thioredoxin-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_001026715.3. COMPLETENESS: incomplete on both ends. |
1 | ATGTCTCTCA CCAAGGAGCC TATTCTGGAG CTTGCTGATA TGAGTGACTT TGAGCAATTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021886.1 |
CDS | 1..345 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026715.4 |
1 | ATGTCTCTCA CCAAGGAGCC TATTCTGGAG CTTGCTGATA TGAGTGACTT TGAGCAATTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa338364 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026715.4 , NM_001026715.5 | |
Accession Version | NM_001026715.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 345bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Thioredoxin-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_001026715.4. |
1 | ATGTCTCTCA CCAAGGAGCC TATTCTGGAG CTTGCTGATA TGAGTGACTT TGAGCAATTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021886.1 |
CDS | 69..413 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026715.5 |
1 | ATGTCTCTCA CCAAGGAGCC TATTCTGGAG CTTGCTGATA TGAGTGACTT TGAGCAATTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |