Gene Symbol | sek-1 |
Entrez Gene ID | 181043 |
Full Name | Dual specificity mitogen-activated protein kinase kinase sek-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » sek-1 cDNA ORF clone
Gene Symbol | sek-1 |
Entrez Gene ID | 181043 |
Full Name | Dual specificity mitogen-activated protein kinase kinase sek-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_076921.5 | NP_509322.2 | Dual specificity mitogen-activated protein kinase kinase sek-1 |
NM_076921.4 | NP_509322.2 | Dual specificity mitogen-activated protein kinase kinase sek-1 |
Homo sapiens (human) | MAP2K6 | NP_002749.2 |
MAP2K6 | XP_001083492.1 | |
Caenorhabditis elegans (roundworm) | sek-1 | NP_509322.2 |
Canis lupus familiaris (dog) | MAP2K6 | XP_005624348.1 |
Rattus norvegicus (Norway rat) | Map2k6 | NP_446155.1 |
Xenopus tropicalis (tropical clawed frog) | map2k6 | NP_001005653.1 |
Bos taurus (cattle) | MAP2K6 | NP_001029217.1 |
Gallus gallus (chicken) | MAP2K6 | XP_003642396.1 |
Danio rerio (zebrafish) | map2k6 | NP_571799.1 |
Pan troglodytes (chimpanzee) | MAP2K6 | XP_523699.2 |
Mus musculus (house mouse) | Map2k6 | NP_036073.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
this study shows that sek-1(-) MAP kinase mutant nematodes succumb to infection faster, suggesting that this signaling pathway plays a role in immune activation
Title: Analysis of the Caenorhabditis elegans innate immune response to Coxiella burnetii.
SEK-1 is key player involved in tannic acid (TA)-mediated longevity. It is conceivable that TA mimics pathogen action and therefore activates the SEK-1-mediated pathogen resistance pathway.
Title: The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis.
Reuslts identify four genes to be required for the quercetin derived lifespan extension in C. elegans, namely age-1, daf-2, unc-43 and sek-1.
Title: Quercetin mediated lifespan extension in Caenorhabditis elegans is modulated by age-1, daf-2, sek-1 and unc-43.
oxidative, osmotic, heat shock and starvation stresses induce germ cell apoptosis through a p53 and EGL-1 independent pathway; the MAPK kinases MEK-1 and SEK-1, and the p53 antagonist protein ABL-1, are essential for stress-induced germ cell apoptosis
Title: Stress-induced germ cell apoptosis by a p53 independent pathway in Caenorhabditis elegans.
The following sek-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sek-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa349614 | |
Clone ID Related Accession (Same CDS sequence) | NM_076921.5 , NM_076921.4 | |
Accession Version | NM_076921.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Dual specificity mitogen-activated protein kinase kinase sek-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Sep 4, 2019 this sequence version replaced NM_076921.4. |
1 | ATGGAGCGAA AAGGACGTGA GCGCAAGCTG CCGGGCATGA AGATCGTGAT GCCAACACCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_509322.2 |
CDS | 71..1081 |
Translation |
Target ORF information:
Target ORF information:
|
NM_076921.5 |
1 | ATGGAGCGAA AAGGACGTGA GCGCAAGCTG CCGGGCATGA AGATCGTGAT GCCAACACCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349614 | |
Clone ID Related Accession (Same CDS sequence) | NM_076921.5 , NM_076921.4 | |
Accession Version | NM_076921.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Dual specificity mitogen-activated protein kinase kinase sek-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_076921.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGAGCGAA AAGGACGTGA GCGCAAGCTG CCGGGCATGA AGATCGTGAT GCCAACACCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_509322.2 |
CDS | 1..1011 |
Translation |
Target ORF information:
Target ORF information:
|
NM_076921.4 |
1 | ATGGAGCGAA AAGGACGTGA GCGCAAGCTG CCGGGCATGA AGATCGTGAT GCCAACACCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |