Gene Symbol | acr-2 |
Entrez Gene ID | 180936 |
Full Name | Acetylcholine receptor subunit beta-type acr-2 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » acr-2 cDNA ORF clone
Gene Symbol | acr-2 |
Entrez Gene ID | 180936 |
Full Name | Acetylcholine receptor subunit beta-type acr-2 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_076727.5 | NP_509128.1 | Acetylcholine receptor subunit beta-type acr-2 |
NM_076727.7 | NP_509128.1 | Acetylcholine receptor subunit beta-type acr-2 |
Danio rerio (zebrafish) | chrnb2a | XP_001343044.4 |
Caenorhabditis elegans (roundworm) | lev-1 | NP_001255705.1 |
Caenorhabditis elegans (roundworm) | acr-3 | NP_509129.1 |
Caenorhabditis elegans (roundworm) | acr-2 | NP_509128.1 |
Caenorhabditis elegans (roundworm) | unc-29 | NP_492399.1 |
Danio rerio (zebrafish) | LOC569662 | XP_698151.5 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
ACR-2(gf) in A and B class motor neurons induces aberrant synchronous activity in both ventral- and dorsal-innervating B and A class motor neurons.
Title: Hyperactivation of B-type motor neurons results in aberrant synchrony of the Caenorhabditis elegans motor circuit.
Yhe behavioral and physiological effects of acr-2(gf) require the activity of the TRPM channel GTL-2 in nonneuronal tissues.
Title: TRPM channels modulate epileptic-like convulsions via systemic ion homeostasis.
excess nAChR activation leads to progressive destabilization of the motor neuron processes and, ultimately, paralysis in these animals
Title: A dominant mutation in a neuronal acetylcholine receptor subunit leads to motor neuron degeneration in Caenorhabditis elegans.
important for the coordinated excitation and inhibition of body muscles underlying sinusoidal movement
Title: A neuronal acetylcholine receptor regulates the balance of muscle excitation and inhibition in Caenorhabditis elegans.
The following acr-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the acr-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa349818 | |
Clone ID Related Accession (Same CDS sequence) | NM_076727.5 , NM_076727.7 | |
Accession Version | NM_076727.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1728bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Acetylcholine receptor subunit beta-type acr-2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_076727.4. COMPLETENESS: incomplete on both ends. |
1 | ATGAAGAAGA CGGTCAAAAT ATTACTTATT CTGATCACAG TATTTCTTAA AGTGCACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_509128.1 |
CDS | 1..1728 |
Translation |
Target ORF information:
Target ORF information:
|
NM_076727.5 |
1 | ATGAAGAAGA CGGTCAAAAT ATTACTTATT CTGATCACAG TATTTCTTAA AGTGCACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349818 | |
Clone ID Related Accession (Same CDS sequence) | NM_076727.5 , NM_076727.7 | |
Accession Version | NM_076727.7 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1728bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Acetylcholine receptor subunit beta-type acr-2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Oct 18, 2019 this sequence version replaced NM_076727.6. |
1 | ATGAAGAAGA CGGTCAAAAT ATTACTTATT CTGATCACAG TATTTCTTAA AGTGCACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_509128.1 |
CDS | 230..1957 |
Translation |
Target ORF information:
Target ORF information:
|
NM_076727.7 |
1 | ATGAAGAAGA CGGTCAAAAT ATTACTTATT CTGATCACAG TATTTCTTAA AGTGCACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |