Gene Symbol | syg-1 |
Entrez Gene ID | 180555 |
Full Name | Synaptogenesis protein syg-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » syg-1 cDNA ORF clone
Gene Symbol | syg-1 |
Entrez Gene ID | 180555 |
Full Name | Synaptogenesis protein syg-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001373246.2 | NP_001360786.1 | Synaptogenesis protein syg-1 |
NM_001129687.2 | NP_001123159.1 | Synaptogenesis protein syg-1 |
NM_001129687.4 | NP_001123159.1 | Synaptogenesis protein syg-1 |
NM_076056.7 | NP_508457.3 | Synaptogenesis protein syg-1 |
NM_076056.6 | NP_508457.3 | Synaptogenesis protein syg-1 |
Drosophila melanogaster (fruit fly) | kirre | NP_001245505.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP000217 | XP_310917.4 |
Caenorhabditis elegans (roundworm) | syg-1 | NP_508457.3 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Through a series of biochemical, biophysical, and in vivo functional experiments, study finds that the extracellular affinity, docking geometry, and rigidity of the SYG-1 and SYG-2 ectodomains play crucial roles in specifying a functional synaptic architecture in C. elegans.
Title: Extracellular architecture of the SYG-1/SYG-2 adhesion complex instructs synaptogenesis.
Assembly of the F-actin network requires a direct interaction between the synaptic cell adhesion molecule SYG-1 and a key regulator of actin cytoskeleton, the WVE-1/WAVE regulatory complex.
Title: Local F-actin network links synapse formation and axon branching.
Data show that the nephrin/Neph1 orthologs SYG-2 and SYG-1 form intercellular contacts strictly in trans between epithelial guidepost cells and neurons specifying the localization of synapses.
Title: Functional and spatial analysis of C. elegans SYG-1 and SYG-2, orthologs of the Neph/nephrin cell adhesion module directing selective synaptogenesis.
study found stereotyped developmental elimination of synapses in the motor neuron (HSNL) was mediated by a Skp1-cullin-F-box (SCF) complex composed of SKR-1 & SEL-10; SYG-1 bound to SKR-1 & inhibited assembly of the SCF complex, protecting nearby synapses
Title: Spatial regulation of an E3 ubiquitin ligase directs selective synapse elimination.
SYG-2 binds SYG-1, the receptor on HSNL, and directs SYG-1 accumulation and synapse formation to adjacent regions of HSNL.
Title: Synaptic specificity is generated by the synaptic guidepost protein SYG-2 and its receptor, SYG-1.
The following syg-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the syg-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa349912 | |
Clone ID Related Accession (Same CDS sequence) | NM_076056.7 , NM_076056.6 | |
Accession Version | NM_076056.7 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2112bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Synaptogenesis protein syg-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Sep 4, 2019 this sequence version replaced NM_076056.6. COMPLETENESS: incomplete on the 3' end. |
1 | ATGGTACGGT GGCAGACCTG GCCACTGTTG TTGTTGTTTC AACTGGTCAC TTGCCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_508457.3 |
CDS | 9..2120 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGTACGGT GGCAGACCTG GCCACTGTTG TTGTTGTTTC AACTGGTCAC TTGCCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349912 | |
Clone ID Related Accession (Same CDS sequence) | NM_076056.7 , NM_076056.6 | |
Accession Version | NM_076056.6 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2112bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Synaptogenesis protein syg-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_076056.5. COMPLETENESS: incomplete on both ends. |
1 | ATGGTACGGT GGCAGACCTG GCCACTGTTG TTGTTGTTTC AACTGGTCAC TTGCCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_508457.3 |
CDS | 1..2112 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGTACGGT GGCAGACCTG GCCACTGTTG TTGTTGTTTC AACTGGTCAC TTGCCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349913 | |
Clone ID Related Accession (Same CDS sequence) | NM_001129687.2 , NM_001129687.4 | |
Accession Version | NM_001129687.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2193bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Synaptogenesis protein syg-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_001129687.1. COMPLETENESS: incomplete on both ends. |
1 | ATGGTACGGT GGCAGACCTG GCCACTGTTG TTGTTGTTTC AACTGGTCAC TTGCCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123159.1 |
CDS | 1..2193 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGTACGGT GGCAGACCTG GCCACTGTTG TTGTTGTTTC AACTGGTCAC TTGCCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349913 | |
Clone ID Related Accession (Same CDS sequence) | NM_001129687.2 , NM_001129687.4 | |
Accession Version | NM_001129687.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2193bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Synaptogenesis protein syg-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Oct 18, 2019 this sequence version replaced NM_001129687.3. |
1 | ATGGTACGGT GGCAGACCTG GCCACTGTTG TTGTTGTTTC AACTGGTCAC TTGCCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123159.1 |
CDS | 9..2201 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGTACGGT GGCAGACCTG GCCACTGTTG TTGTTGTTTC AACTGGTCAC TTGCCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa851050 | |
Clone ID Related Accession (Same CDS sequence) | NM_001373246.2 | |
Accession Version | NM_001373246.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2184bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Synaptogenesis protein syg-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Oct 18, 2019 this sequence version replaced NM_001373246.1. |
1 | ATGGTACGGT GGCAGACCTG GCCACTGTTG TTGTTGTTTC AACTGGTCAC TTGCCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001360786.1 |
CDS | 9..2192 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGTACGGT GGCAGACCTG GCCACTGTTG TTGTTGTTTC AACTGGTCAC TTGCCAACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |