Gene Symbol | efl-1 |
Entrez Gene ID | 180133 |
Full Name | E2F-like (mammalian transcription factor) |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » efl-1 cDNA ORF clone
Gene Symbol | efl-1 |
Entrez Gene ID | 180133 |
Full Name | E2F-like (mammalian transcription factor) |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_074888.6 | NP_507289.1 | E2F_TDP domain-containing protein |
NM_074888.5 | NP_507289.1 | E2F-like (mammalian transcription factor) |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
E2F and HSF-1 directly regulate a gene network, including a specific subset of chaperones, to promote protein biogenesis and anabolic metabolism, which are essential in development.
Title: E2F coregulates an essential HSF developmental program that is distinct from the heat-shock response.
Efl-1 regulates organismal senescence by inhibiting daf-16.
Title: E2F transcription factor 1 regulates cellular and organismal senescence by inhibiting Forkhead box O transcription factors.
dpl-1 and mcd-1 act with efl-1 E2F and lin-35 Rb to promote programmed cell death and do so by regulating the killing process rather than by affecting the decision between survival and death.
Title: DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans.
Many EFL-1/DPL-1 responsive genes encode proteins required for oogenesis and early embryogenesis, rather than cell cycle components.
Title: Promotion of oogenesis and embryogenesis in the C. elegans gonad by EFL-1/DPL-1 (E2F) does not require LIN-35 (pRB).
Efl-1/E2F and other SynMuv B genes negatively regulate a component of the anaphase-promoting complex or cyclosome (APC/C).
Title: Caenorhabditis elegans lin-35/Rb, efl-1/E2F and other synthetic multivulva genes negatively regulate the anaphase-promoting complex gene mat-3/APC8.
The following efl-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the efl-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa346166 | |
Clone ID Related Accession (Same CDS sequence) | NM_074888.6 , NM_074888.5 | |
Accession Version | NM_074888.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | E2F_TDP domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_074888.5. |
1 | ATGGAAGACT CGTACAACGA CATGGAAGAC CCCGGCTTCC GCCAATTATC TGACATGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_507289.1 |
CDS | 3..1031 |
Translation |
Target ORF information:
Target ORF information:
|
NM_074888.6 |
1 | ATGGAAGACT CGTACAACGA CATGGAAGAC CCCGGCTTCC GCCAATTATC TGACATGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa346166 | |
Clone ID Related Accession (Same CDS sequence) | NM_074888.6 , NM_074888.5 | |
Accession Version | NM_074888.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | E2F-like (mammalian transcription factor) | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_074888.4. COMPLETENESS: incomplete on both ends. |
1 | ATGGAAGACT CGTACAACGA CATGGAAGAC CCCGGCTTCC GCCAATTATC TGACATGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_507289.1 |
CDS | 1..1029 |
Translation |
Target ORF information:
Target ORF information:
|
NM_074888.5 |
1 | ATGGAAGACT CGTACAACGA CATGGAAGAC CCCGGCTTCC GCCAATTATC TGACATGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |