Gene Symbol | egl-9 |
Entrez Gene ID | 179461 |
Full Name | Hypoxia-inducible factor prolyl hydroxylase |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » egl-9 cDNA ORF clone
Gene Symbol | egl-9 |
Entrez Gene ID | 179461 |
Full Name | Hypoxia-inducible factor prolyl hydroxylase |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001028663.3 | NP_001023834.1 | Hypoxia-inducible factor prolyl hydroxylase |
NM_001028662.1 | NP_001023833.1 | Hypoxia-inducible factor prolyl hydroxylase |
NM_001373098.1 | NP_001359645.1 | Hypoxia-inducible factor prolyl hydroxylase |
NM_001028663.4 | NP_001023834.1 | Hypoxia-inducible factor prolyl hydroxylase |
NM_001047640.3 | NP_001041105.1 | Hypoxia-inducible factor prolyl hydroxylase |
NM_171533.4 | NP_741621.1 | Hypoxia-inducible factor prolyl hydroxylase |
NM_001028661.3 | NP_001023832.1 | Hypoxia-inducible factor prolyl hydroxylase |
NM_001047640.2 | NP_001041105.1 | Hypoxia-inducible factor prolyl hydroxylase |
NM_171533.5 | NP_741621.1 | Hypoxia-inducible factor prolyl hydroxylase |
NM_001028662.2 | NP_001023833.1 | Hypoxia-inducible factor prolyl hydroxylase |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
study demonstrated that loss of egl-9, a negative regulator of HIF, confers HIF-dependent enhanced susceptibility to S. aureus while increasing resistance to Pseudomonas aeruginosa
Title: EGL-9 controls C. elegans host defense specificity through prolyl hydroxylation-dependent and -independent HIF-1 pathways.
These data support a model in which SWAN-1, MBK-1 and EGL-9 regulate HIF-1 transcriptional activity and modulate C. elegans resistance to P. aeruginosa PAO1 fast killing.
Title: C. elegans SWAN-1 Binds to EGL-9 and regulates HIF-1-mediated resistance to the bacterial pathogen Pseudomonas aeruginosa PAO1.
Data show that EGL-9 inhibits HIF-1 transcriptional activity via a pathway that has little or no requirement for hydroxylase activity or for the EGL-9 MYND domain.
Title: Two distinct roles for EGL-9 in the regulation of HIF-1-mediated gene expression in Caenorhabditis elegans.
The following egl-9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the egl-9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa346494 | |
Clone ID Related Accession (Same CDS sequence) | NM_001373098.1 , NM_001028661.3 | |
Accession Version | NM_001373098.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1092bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Hypoxia-inducible factor prolyl hydroxylase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). |
1 | ATGAGCAGTG CCCCAAATGA TGACTGTGAG ATCGACAAGG GAACACCTTC TACCGCTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001359645.1 |
CDS | 9..1100 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001373098.1 |
1 | ATGAGCAGTG CCCCAAATGA TGACTGTGAG ATCGACAAGG GAACACCTTC TACCGCTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa346494 | |
Clone ID Related Accession (Same CDS sequence) | NM_001373098.1 , NM_001028661.3 | |
Accession Version | NM_001028661.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1092bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Hypoxia-inducible factor prolyl hydroxylase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_001028661.2. COMPLETENESS: incomplete on both ends. |
1 | ATGAGCAGTG CCCCAAATGA TGACTGTGAG ATCGACAAGG GAACACCTTC TACCGCTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001023832.1 |
CDS | 1..1092 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001028661.3 |
1 | ATGAGCAGTG CCCCAAATGA TGACTGTGAG ATCGACAAGG GAACACCTTC TACCGCTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa347959 | |
Clone ID Related Accession (Same CDS sequence) | NM_001028662.1 , NM_001028662.2 | |
Accession Version | NM_001028662.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1398bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Hypoxia-inducible factor prolyl hydroxylase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). COMPLETENESS: incomplete on both ends. |
1 | ATGCCATTGC GTACAATTGT GGCACCAACA TCATACGGTA TCCCCACACC AATGCCATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001023833.1 |
CDS | 1..1398 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001028662.1 |
1 | ATGCCATTGC GTACAATTGT GGCACCAACA TCATACGGTA TCCCCACACC AATGCCATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa347959 | |
Clone ID Related Accession (Same CDS sequence) | NM_001028662.1 , NM_001028662.2 | |
Accession Version | NM_001028662.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1398bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Hypoxia-inducible factor prolyl hydroxylase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_001028662.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGCCATTGC GTACAATTGT GGCACCAACA TCATACGGTA TCCCCACACC AATGCCATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001023833.1 |
CDS | 1..1398 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001028662.2 |
1 | ATGCCATTGC GTACAATTGT GGCACCAACA TCATACGGTA TCCCCACACC AATGCCATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa344952 | |
Clone ID Related Accession (Same CDS sequence) | NM_171533.4 , NM_171533.5 | |
Accession Version | NM_171533.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2172bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Hypoxia-inducible factor prolyl hydroxylase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_171533.3. COMPLETENESS: incomplete on both ends. |
1 | ATGAGCAGTG CCCCAAATGA TGACTGTGAG ATCGACAAGG GAACACCTTC TACCGCTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_741621.1 |
CDS | 1..2172 |
Translation |
Target ORF information:
Target ORF information:
|
NM_171533.4 |
1 | ATGAGCAGTG CCCCAAATGA TGACTGTGAG ATCGACAAGG GAACACCTTC TACCGCTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa344952 | |
Clone ID Related Accession (Same CDS sequence) | NM_171533.4 , NM_171533.5 | |
Accession Version | NM_171533.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2172bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Hypoxia-inducible factor prolyl hydroxylase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_171533.4. |
1 | ATGAGCAGTG CCCCAAATGA TGACTGTGAG ATCGACAAGG GAACACCTTC TACCGCTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_741621.1 |
CDS | 9..2180 |
Translation |
Target ORF information:
Target ORF information:
|
NM_171533.5 |
1 | ATGAGCAGTG CCCCAAATGA TGACTGTGAG ATCGACAAGG GAACACCTTC TACCGCTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa346608 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047640.3 , NM_001047640.2 | |
Accession Version | NM_001047640.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Hypoxia-inducible factor prolyl hydroxylase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_001047640.2. COMPLETENESS: incomplete on the 5' end. |
1 | ATGATATGCA AGTCACTTCA AACAAGTGGC ATGGTGCCAA GTAATTTGAT GCCTCAGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001041105.1 |
CDS | 1..1944 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047640.3 |
1 | ATGATATGCA AGTCACTTCA AACAAGTGGC ATGGTGCCAA GTAATTTGAT GCCTCAGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa346608 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047640.3 , NM_001047640.2 | |
Accession Version | NM_001047640.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Hypoxia-inducible factor prolyl hydroxylase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_001047640.1. COMPLETENESS: incomplete on both ends. |
1 | ATGATATGCA AGTCACTTCA AACAAGTGGC ATGGTGCCAA GTAATTTGAT GCCTCAGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001041105.1 |
CDS | 1..1944 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047640.2 |
1 | ATGATATGCA AGTCACTTCA AACAAGTGGC ATGGTGCCAA GTAATTTGAT GCCTCAGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa347951 | |
Clone ID Related Accession (Same CDS sequence) | NM_001028663.3 , NM_001028663.4 | |
Accession Version | NM_001028663.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2109bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Hypoxia-inducible factor prolyl hydroxylase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_001028663.2. COMPLETENESS: incomplete on both ends. |
1 | ATGAGCAGTG CCCCAAATGA TGACTGTGAG ATCGACAAGG GAACACCTTC TACCGCTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001023834.1 |
CDS | 1..2109 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001028663.3 |
1 | ATGAGCAGTG CCCCAAATGA TGACTGTGAG ATCGACAAGG GAACACCTTC TACCGCTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa347951 | |
Clone ID Related Accession (Same CDS sequence) | NM_001028663.3 , NM_001028663.4 | |
Accession Version | NM_001028663.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2109bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Hypoxia-inducible factor prolyl hydroxylase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_001028663.3. |
1 | ATGAGCAGTG CCCCAAATGA TGACTGTGAG ATCGACAAGG GAACACCTTC TACCGCTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001023834.1 |
CDS | 9..2117 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001028663.4 |
1 | ATGAGCAGTG CCCCAAATGA TGACTGTGAG ATCGACAAGG GAACACCTTC TACCGCTTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |