hcp-2 cDNA ORF clone, Caenorhabditis elegans

Gene
Clones
gRNAs

Summary

Gene Symbol	hcp-2
Entrez Gene ID	179353
Full Name	HoloCentric chromosome binding Protein
Gene Type	protein-coding
Organism	Caenorhabditis elegans

mRNA and Protein(s)

mRNA	Protein	Name
NM_073088.4	NP_505489.1	HoloCentric chromosome binding Protein
NM_073088.3	NP_505489.1	HoloCentric chromosome binding Protein

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.

Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

show that HCP-1 and HCP-2 recently implicated in the spindle assembly checkpoint (SAC) function, do not have identical functions, since hcp-1(RNAi), but not hcp-2(RNAi), enhances the lethality of the spindle assembly checkpoint components mutants
Title: Synthetic lethal interactions identify phenotypic "interologs" of the spindle assembly checkpoint components.

The key role of HCP-1/2 is to target CLASP(CLS-2) to kinetochores to mediate chromosome segregation.
Title: The CENP-F-like proteins HCP-1 and HCP-2 target CLASP to kinetochores to mediate chromosome segregation.

The following hcp-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the hcp-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCa348237	NM_073088.4 Latest version!	Caenorhabditis elegans HoloCentric chromosome binding Protein (hcp-2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
View Old Accession Versions >>
OCa348237	NM_073088.3	Caenorhabditis elegans HoloCentric chromosome binding Protein (hcp-2), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

hcp-2 ( NM_073088.4 ) cDNA ORF clone, Caenorhabditis elegans -> NP_505489.1 Caenorhabditis elegans HoloCentric chromosome binding Protein (hcp-2), mRNA.

Price & Availability↑

CloneID	OCa348237
Clone ID Related Accession (Same CDS sequence)	NM_073088.4 , NM_073088.3
Accession Version	NM_073088.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-17
Organism	Caenorhabditis elegans
Product	HoloCentric chromosome binding Protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_073088.3.

ATGGAGGAAA GTACAAACGA CGGCGATGAA AACAAGCCTG CAACTGGGAA GAAGCGACAA 
CAGCTTGAAT CTCCGTTTTC TGCTGCGACA CCGAAATCGC GTCTCGGAAA GGAATCGAAA 
AGGTTTTTCG GGCGTTCTGC TATGAATTTG GCCGATGGAA ATCTTGAAGA AACTCGCATT 
GAGCCAGACT CGCGCCATTC GTCTACCAGT ACCTCCGACT CTATTCTTGA TGATTCTTCA 
ATCTCCAATT TTTCCACACT CGCCCCGCCA AATACCTCCG TTGATGATAA CAGTGTCTGT 
GAACCGCCAA GAGCTTCCTC AGCTCATGAT GTCGATCCTA ATTTGGAACA AACGAAGGTT 
TACAGTGAAG ACAGCATCAG CAAAGACTGT AGCATTGCTG ACGAGAGTTT TGCGACTGAT 
GGTGACGTCA CACTGGCGAA CGACTTCTTC CAACAAGCAA CGATTCAAGA TCTAGAGAAT 
ACTCCGTCAA CACCACTTCG GAGCCAGACA CAAGTTGGAG ACGAAAGTAC ACCAACTGCT 
CCTTCCCCAC TTCGTTCGAA AATTCCAATC GAGAGTGAGG TTGTGCAGTC AACTTCTGTA 
GAGTCAGTTC AGTCAACATC TCAGCATGAA AAATCGAGAA TTGAATATTC TTTATATGAA 
TTCGAAATGC TGGAGAAAAA TATCGAGCAT GATGAAGTCG TTAAAGATCT TCAATTGAAA 
ATTGAACTTC TTGGAGAGAA ACATAGACAA ACTCTTGTTG AAATTAAAGA AGCTCGTGAA 
GTTGAAGAGA AAATGCTCAT GCAACAAGTG GAGGAGGCTG TAAAAAAGAC GAAATCTGAG 
CGCGAAGCTG CAAAAACTCT GGAACAACTT CTTGAGAAAC GGATTGAAGA GCTCGAGATG 
AAATTAACGG AGCCGAACGG AGAGAAACTA CAGTTTGAAC ATCAGTTGGA AGAGTTGAAG 
AGTCGTTGTG AAGAGCTTAC TGACAAAGCA CTGAAGGTTG ATGTCATGCA ACACAGCATT 
GAGGACTACG AAAAAAAGTT TGTGGAGTTG CAAGAAATGA AAGAGGAGGC TGATGAACAA 
CTGCAAAAGG CTAAGGAAGA CATTGAGACA CTACAGATGA AGTATGTGGA ATTGGAGACA 
ACGATCAACA AAGAGGTGTT CTCCAACTCT GAAATTGAAA CTCTGAAGTC GGAACATGAA 
ATTGTTCGTA AACTGATGTT GGATGAAATC CATCGTCTTG AGAATGAAAT GTCTGCTCTT 
CAACCGAAGA ATGATACTAC TGAACTGGAA GAACTTCAGA AGACTCTCGA TGATCTCAAA 
ATTGACTGTT GCAATTTGAC TTCAAAAATG CTTGAACTTC AGTCAGAGCT CGTAGAAGTG 
AAAGAGAAAG CCACGTCAGA AATTGGGGAA GCTGTTCAGA AAAACGGTGA ACTCCTGGAA 
CAGATCAATA GCCTTCGCGT CGAAAATGCA AAATTGGTGG ACATGGAAGG TCAGCTAAAC 
GATGCACATC GTAAAGCGGA AGATAAAGAT GTTCGAATCA GTGAACTATT GACTACCATT 
GAGTCTCTTC GTCAAGATTC TGAGGCCAGC GATAAACTTC TAATGGATTC GGAGTCTACA 
CAAAATGAGT ATTCGCTTGC TCTTGAAAAC ACAGTCTCTG AGTTGGAAAC AATGCGAAGA 
GAATATAAGG CTTCGGTGGA TAAAGTTTGC AGTCTTCAAC TGGAACTAGA AGAAATTCAA 
CATGAAACAT CAGTTGAATT GGAAGAGGCG GAAATAAGAA TTAAAGAATT GGAGTTGGCA 
CAAGAAGAAG CTGTAAAAAC TGGAAGTTCA CAGCTCAAGA AGCTAGAAAT TGTTCAAGAA 
GATTGTCAGA AGCTTCGTGA TCAATTGAAG GAGGAACAAA TTCAGCAACT TGTATCTCTT 
CGCGAGACTT CTGAAGTCAT GCACCAGGAA TCGGCTCGAC ATCAAGAAGA AAAGTACCAG 
ATTCAGAGCA AGTTGATGTC GACGGAAGCA GAAGTTATTG AGCTGAGATC CTCTATTGAT 
TCTCTCCAAG CTGAAGTTCG AGTGCAGTCA GATTCCGCCG CAGACCAAAA ACACATCCTT 
GAAGATTATT TGAGAAAAAT TCGGCAAGCA GAGGAAACCA ACGAAAAACT TCGCTCTGAT 
TTGGCCTCCT CTGAAGAACA AATTCTAGAT CTGAAGAATC AACAGGAATC ATTGATTGAT 
GATTTGAAGG AAAAATTGCA CTCTGCAGAA AGTACGAATC AAGAATTGCA GGTCTCTCTG 
GAGATGCTCA AGATAGAAGT CAGTAATGCT CGTCAGAAAG TGATGGAGAG TGAGGTTTTA 
AAAGAATCTT TCGAAGCCCT TCAACTGGAG TTGTCGGCAT CACAAGAAGT TTCTCGATCA 
GTGGTTGATG CTGCAGTTCA AGAAAAAGAT GGTCTTCTGA GACTGGTGGA TACGCTGAAG 
TTGAAAATTG AAGATACGGA AAAGTCTGCT CAAGATCTTC AACAAAGCTC TGTGGAAGAG 
ATAAAACAAC TTCAATTGGA CCTTCAAAAT TTCAAACAAA ATGCTGAAGT TCTCGAATCT 
CTGAATGAAA AACTAAATTC TAGTCACAAG AGGGATATGG TGGCGTTGGC ATCTCAACTA 
GAAGAGCTTC AACATAAACT CGTCGTCGGA GAATCCCAAG TGGAAAATGT TAAGGAAGAA 
CTGATTGGAG CTAAGATAAT GAACAAGGAA ATGGTTGATG AACTGAATGC GAAGCTTGGG 
GATGCTCTTG AAGGGATGGA AGAACTGAAA AAGAGCCTAG AAGTATCCGA AGCTAAAGTT 
CAGAGAAGAG AAGAAGAGCT AATCGCTCAA GTATCGAAAC ATCGTGATCA GCAGGAGCAG 
CTTCAATTGA CTCTCGACGA GCTCAAATCG GCTCAACATT CCACGGAAAC ATCCCGTTCC 
CAGTCAAATG AACTTGCTGC TCGTATCGAA GAGCTTGAAG CTTCCATCTC CTTTGCACAG 
AAGGCTCTTC AAGATGTAGA AGACGTCAAA CATCAACAAG ACATTCAGAT ATCTGAGGCG 
AATGAGGCAA TGGTAAAGCT GAAGCAAGAC TTTGAGACAG AGAGGACATC ACTTCAAAAC 
GAGTTCAACC AAACTGTTTC CGCAGACAAA GAGCAGCTTG GTCATGCTGA ACAAATGATT 
GCTCAGAAAG AAAAAGAGAT TATCACTCTC CAAGCTCGAA TCGAAGCGAT GTCTCAGCAG 
TTCGAGGAGC GCCTTGAAGC ATCGAATGTT TGGAAGACCC AAGCCATGAA TGTCGGTACA 
CTGACTGAAT CGTTGTCTCA GTTACAAGTA CAACTTCAAC AAATGAATGA GAAGCTGGTT 
GCATCGGACA AATACGCAGT TGAAGTGGAG CAGCAAGCTC AGCATGATAT AACTGTGATC 
CAGGAAGAGA AGAACGAGCA ATCAGCGGCT CTAGAAGAAG CACTATCCAA AATAGCGGAA 
CTTGAGGAGC AACTGGGAAG AGCCCAGAAG GAGATTGTAC GACTCGAGAA GGTGTGTGAC 
GATTTCGACG ACGTTGAACG AGAGCTGAAG GATGCCATCT CGAAGCTTCA ATCTGAGATA 
AAGCAATTGA AAGGAATCAA GAAACCACCA AAAGTAATGG GACTCCTTCA ACAGGCCAGA 
CTTGGAGTGA AGCCGCTGAG TCGTGAACAT TCTCATGCGG AGCCACCAGA GCCTGTTGTT 
GAGGACAAGT TCGAAGATGC TCAGGATTCG TTCCAAGAAG AGTTTTCCCA TTCGCCAGAT 
GCTATCACGT CATCTACGGT ACTCCATCCA GATGATCATC TTCAAGAAAC AACTGCAGTT 
GAAACGCCGT CGAAGAAGGC GAACCGCTCA AACTGCAACC AGCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_505489.1
CDS	137..4024
Translation	MEESTNDGDENKPATGKKRQQLESPFSAATPKSRLGKESKRFFGRSAMNLADGNLEETRIEPDSRHSSTSTSDSILDDSSISNFSTLAPPNTSVDDNSVCEPPRASSAHDVDPNLEQTKVYSEDSISKDCSIADESFATDGDVTLANDFFQQATIQDLENTPSTPLRSQTQVGDESTPTAPSPLRSKIPIESEVVQSTSVESVQSTSQHEKSRIEYSLYEFEMLEKNIEHDEVVKDLQLKIELLGEKHRQTLVEIKEAREVEEKMLMQQVEEAVKKTKSEREAAKTLEQLLEKRIEELEMKLTEPNGEKLQFEHQLEELKSRCEELTDKALKVDVMQHSIEDYEKKFVELQEMKEEADEQLQKAKEDIETLQMKYVELETTINKEVFSNSEIETLKSEHEIVRKLMLDEIHRLENEMSALQPKNDTTELEELQKTLDDLKIDCCNLTSKMLELQSELVEVKEKATSEIGEAVQKNGELLEQINSLRVENAKLVDMEGQLNDAHRKAEDKDVRISELLTTIESLRQDSEASDKLLMDSESTQNEYSLALENTVSELETMRREYKASVDKVCSLQLELEEIQHETSVELEEAEIRIKELELAQEEAVKTGSSQLKKLEIVQEDCQKLRDQLKEEQIQQLVSLRETSEVMHQESARHQEEKYQIQSKLMSTEAEVIELRSSIDSLQAEVRVQSDSAADQKHILEDYLRKIRQAEETNEKLRSDLASSEEQILDLKNQQESLIDDLKEKLHSAESTNQELQVSLEMLKIEVSNARQKVMESEVLKESFEALQLELSASQEVSRSVVDAAVQEKDGLLRLVDTLKLKIEDTEKSAQDLQQSSVEEIKQLQLDLQNFKQNAEVLESLNEKLNSSHKRDMVALASQLEELQHKLVVGESQVENVKEELIGAKIMNKEMVDELNAKLGDALEGMEELKKSLEVSEAKVQRREEELIAQVSKHRDQQEQLQLTLDELKSAQHSTETSRSQSNELAARIEELEASISFAQKALQDVEDVKHQQDIQISEANEAMVKLKQDFETERTSLQNEFNQTVSADKEQLGHAEQMIAQKEKEIITLQARIEAMSQQFEERLEASNVWKTQAMNVGTLTESLSQLQVQLQQMNEKLVASDKYAVEVEQQAQHDITVIQEEKNEQSAALEEALSKIAELEEQLGRAQKEIVRLEKVCDDFDDVERELKDAISKLQSEIKQLKGIKKPPKVMGLLQQARLGVKPLSREHSHAEPPEPVVEDKFEDAQDSFQEEFSHSPDAITSSTVLHPDDHLQETTAVETPSKKANRSNCNQQ

Target ORF information:

RefSeq Version	NM_073088.4
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans HoloCentric chromosome binding Protein (hcp-2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_073088.4

ORF Insert Sequence:

ATGGAGGAAA GTACAAACGA CGGCGATGAA AACAAGCCTG CAACTGGGAA GAAGCGACAA 
CAGCTTGAAT CTCCGTTTTC TGCTGCGACA CCGAAATCGC GTCTCGGAAA GGAATCGAAA 
AGGTTTTTCG GGCGTTCTGC TATGAATTTG GCCGATGGAA ATCTTGAAGA AACTCGCATT 
GAGCCAGACT CGCGCCATTC GTCTACCAGT ACCTCCGACT CTATTCTTGA TGATTCTTCA 
ATCTCCAATT TTTCCACACT CGCCCCGCCA AATACCTCCG TTGATGATAA CAGTGTCTGT 
GAACCGCCAA GAGCTTCCTC AGCTCATGAT GTCGATCCTA ATTTGGAACA AACGAAGGTT 
TACAGTGAAG ACAGCATCAG CAAAGACTGT AGCATTGCTG ACGAGAGTTT TGCGACTGAT 
GGTGACGTCA CACTGGCGAA CGACTTCTTC CAACAAGCAA CGATTCAAGA TCTAGAGAAT 
ACTCCGTCAA CACCACTTCG GAGCCAGACA CAAGTTGGAG ACGAAAGTAC ACCAACTGCT 
CCTTCCCCAC TTCGTTCGAA AATTCCAATC GAGAGTGAGG TTGTGCAGTC AACTTCTGTA 
GAGTCAGTTC AGTCAACATC TCAGCATGAA AAATCGAGAA TTGAATATTC TTTATATGAA 
TTCGAAATGC TGGAGAAAAA TATCGAGCAT GATGAAGTCG TTAAAGATCT TCAATTGAAA 
ATTGAACTTC TTGGAGAGAA ACATAGACAA ACTCTTGTTG AAATTAAAGA AGCTCGTGAA 
GTTGAAGAGA AAATGCTCAT GCAACAAGTG GAGGAGGCTG TAAAAAAGAC GAAATCTGAG 
CGCGAAGCTG CAAAAACTCT GGAACAACTT CTTGAGAAAC GGATTGAAGA GCTCGAGATG 
AAATTAACGG AGCCGAACGG AGAGAAACTA CAGTTTGAAC ATCAGTTGGA AGAGTTGAAG 
AGTCGTTGTG AAGAGCTTAC TGACAAAGCA CTGAAGGTTG ATGTCATGCA ACACAGCATT 
GAGGACTACG AAAAAAAGTT TGTGGAGTTG CAAGAAATGA AAGAGGAGGC TGATGAACAA 
CTGCAAAAGG CTAAGGAAGA CATTGAGACA CTACAGATGA AGTATGTGGA ATTGGAGACA 
ACGATCAACA AAGAGGTGTT CTCCAACTCT GAAATTGAAA CTCTGAAGTC GGAACATGAA 
ATTGTTCGTA AACTGATGTT GGATGAAATC CATCGTCTTG AGAATGAAAT GTCTGCTCTT 
CAACCGAAGA ATGATACTAC TGAACTGGAA GAACTTCAGA AGACTCTCGA TGATCTCAAA 
ATTGACTGTT GCAATTTGAC TTCAAAAATG CTTGAACTTC AGTCAGAGCT CGTAGAAGTG 
AAAGAGAAAG CCACGTCAGA AATTGGGGAA GCTGTTCAGA AAAACGGTGA ACTCCTGGAA 
CAGATCAATA GCCTTCGCGT CGAAAATGCA AAATTGGTGG ACATGGAAGG TCAGCTAAAC 
GATGCACATC GTAAAGCGGA AGATAAAGAT GTTCGAATCA GTGAACTATT GACTACCATT 
GAGTCTCTTC GTCAAGATTC TGAGGCCAGC GATAAACTTC TAATGGATTC GGAGTCTACA 
CAAAATGAGT ATTCGCTTGC TCTTGAAAAC ACAGTCTCTG AGTTGGAAAC AATGCGAAGA 
GAATATAAGG CTTCGGTGGA TAAAGTTTGC AGTCTTCAAC TGGAACTAGA AGAAATTCAA 
CATGAAACAT CAGTTGAATT GGAAGAGGCG GAAATAAGAA TTAAAGAATT GGAGTTGGCA 
CAAGAAGAAG CTGTAAAAAC TGGAAGTTCA CAGCTCAAGA AGCTAGAAAT TGTTCAAGAA 
GATTGTCAGA AGCTTCGTGA TCAATTGAAG GAGGAACAAA TTCAGCAACT TGTATCTCTT 
CGCGAGACTT CTGAAGTCAT GCACCAGGAA TCGGCTCGAC ATCAAGAAGA AAAGTACCAG 
ATTCAGAGCA AGTTGATGTC GACGGAAGCA GAAGTTATTG AGCTGAGATC CTCTATTGAT 
TCTCTCCAAG CTGAAGTTCG AGTGCAGTCA GATTCCGCCG CAGACCAAAA ACACATCCTT 
GAAGATTATT TGAGAAAAAT TCGGCAAGCA GAGGAAACCA ACGAAAAACT TCGCTCTGAT 
TTGGCCTCCT CTGAAGAACA AATTCTAGAT CTGAAGAATC AACAGGAATC ATTGATTGAT 
GATTTGAAGG AAAAATTGCA CTCTGCAGAA AGTACGAATC AAGAATTGCA GGTCTCTCTG 
GAGATGCTCA AGATAGAAGT CAGTAATGCT CGTCAGAAAG TGATGGAGAG TGAGGTTTTA 
AAAGAATCTT TCGAAGCCCT TCAACTGGAG TTGTCGGCAT CACAAGAAGT TTCTCGATCA 
GTGGTTGATG CTGCAGTTCA AGAAAAAGAT GGTCTTCTGA GACTGGTGGA TACGCTGAAG 
TTGAAAATTG AAGATACGGA AAAGTCTGCT CAAGATCTTC AACAAAGCTC TGTGGAAGAG 
ATAAAACAAC TTCAATTGGA CCTTCAAAAT TTCAAACAAA ATGCTGAAGT TCTCGAATCT 
CTGAATGAAA AACTAAATTC TAGTCACAAG AGGGATATGG TGGCGTTGGC ATCTCAACTA 
GAAGAGCTTC AACATAAACT CGTCGTCGGA GAATCCCAAG TGGAAAATGT TAAGGAAGAA 
CTGATTGGAG CTAAGATAAT GAACAAGGAA ATGGTTGATG AACTGAATGC GAAGCTTGGG 
GATGCTCTTG AAGGGATGGA AGAACTGAAA AAGAGCCTAG AAGTATCCGA AGCTAAAGTT 
CAGAGAAGAG AAGAAGAGCT AATCGCTCAA GTATCGAAAC ATCGTGATCA GCAGGAGCAG 
CTTCAATTGA CTCTCGACGA GCTCAAATCG GCTCAACATT CCACGGAAAC ATCCCGTTCC 
CAGTCAAATG AACTTGCTGC TCGTATCGAA GAGCTTGAAG CTTCCATCTC CTTTGCACAG 
AAGGCTCTTC AAGATGTAGA AGACGTCAAA CATCAACAAG ACATTCAGAT ATCTGAGGCG 
AATGAGGCAA TGGTAAAGCT GAAGCAAGAC TTTGAGACAG AGAGGACATC ACTTCAAAAC 
GAGTTCAACC AAACTGTTTC CGCAGACAAA GAGCAGCTTG GTCATGCTGA ACAAATGATT 
GCTCAGAAAG AAAAAGAGAT TATCACTCTC CAAGCTCGAA TCGAAGCGAT GTCTCAGCAG 
TTCGAGGAGC GCCTTGAAGC ATCGAATGTT TGGAAGACCC AAGCCATGAA TGTCGGTACA 
CTGACTGAAT CGTTGTCTCA GTTACAAGTA CAACTTCAAC AAATGAATGA GAAGCTGGTT 
GCATCGGACA AATACGCAGT TGAAGTGGAG CAGCAAGCTC AGCATGATAT AACTGTGATC 
CAGGAAGAGA AGAACGAGCA ATCAGCGGCT CTAGAAGAAG CACTATCCAA AATAGCGGAA 
CTTGAGGAGC AACTGGGAAG AGCCCAGAAG GAGATTGTAC GACTCGAGAA GGTGTGTGAC 
GATTTCGACG ACGTTGAACG AGAGCTGAAG GATGCCATCT CGAAGCTTCA ATCTGAGATA 
AAGCAATTGA AAGGAATCAA GAAACCACCA AAAGTAATGG GACTCCTTCA ACAGGCCAGA 
CTTGGAGTGA AGCCGCTGAG TCGTGAACAT TCTCATGCGG AGCCACCAGA GCCTGTTGTT 
GAGGACAAGT TCGAAGATGC TCAGGATTCG TTCCAAGAAG AGTTTTCCCA TTCGCCAGAT 
GCTATCACGT CATCTACGGT ACTCCATCCA GATGATCATC TTCAAGAAAC AACTGCAGTT 
GAAACGCCGT CGAAGAAGGC GAACCGCTCA AACTGCAACC AGCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

hcp-2 ( NM_073088.3 ) cDNA ORF clone, Caenorhabditis elegans -> NP_505489.1 Caenorhabditis elegans HoloCentric chromosome binding Protein (hcp-2), partial mRNA.

Price & Availability↑

CloneID	OCa348237
Clone ID Related Accession (Same CDS sequence)	NM_073088.4 , NM_073088.3
Accession Version	NM_073088.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-08
Organism	Caenorhabditis elegans
Product	HoloCentric chromosome binding Protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_073088.2. COMPLETENESS: incomplete on both ends.

ATGGAGGAAA GTACAAACGA CGGCGATGAA AACAAGCCTG CAACTGGGAA GAAGCGACAA 
CAGCTTGAAT CTCCGTTTTC TGCTGCGACA CCGAAATCGC GTCTCGGAAA GGAATCGAAA 
AGGTTTTTCG GGCGTTCTGC TATGAATTTG GCCGATGGAA ATCTTGAAGA AACTCGCATT 
GAGCCAGACT CGCGCCATTC GTCTACCAGT ACCTCCGACT CTATTCTTGA TGATTCTTCA 
ATCTCCAATT TTTCCACACT CGCCCCGCCA AATACCTCCG TTGATGATAA CAGTGTCTGT 
GAACCGCCAA GAGCTTCCTC AGCTCATGAT GTCGATCCTA ATTTGGAACA AACGAAGGTT 
TACAGTGAAG ACAGCATCAG CAAAGACTGT AGCATTGCTG ACGAGAGTTT TGCGACTGAT 
GGTGACGTCA CACTGGCGAA CGACTTCTTC CAACAAGCAA CGATTCAAGA TCTAGAGAAT 
ACTCCGTCAA CACCACTTCG GAGCCAGACA CAAGTTGGAG ACGAAAGTAC ACCAACTGCT 
CCTTCCCCAC TTCGTTCGAA AATTCCAATC GAGAGTGAGG TTGTGCAGTC AACTTCTGTA 
GAGTCAGTTC AGTCAACATC TCAGCATGAA AAATCGAGAA TTGAATATTC TTTATATGAA 
TTCGAAATGC TGGAGAAAAA TATCGAGCAT GATGAAGTCG TTAAAGATCT TCAATTGAAA 
ATTGAACTTC TTGGAGAGAA ACATAGACAA ACTCTTGTTG AAATTAAAGA AGCTCGTGAA 
GTTGAAGAGA AAATGCTCAT GCAACAAGTG GAGGAGGCTG TAAAAAAGAC GAAATCTGAG 
CGCGAAGCTG CAAAAACTCT GGAACAACTT CTTGAGAAAC GGATTGAAGA GCTCGAGATG 
AAATTAACGG AGCCGAACGG AGAGAAACTA CAGTTTGAAC ATCAGTTGGA AGAGTTGAAG 
AGTCGTTGTG AAGAGCTTAC TGACAAAGCA CTGAAGGTTG ATGTCATGCA ACACAGCATT 
GAGGACTACG AAAAAAAGTT TGTGGAGTTG CAAGAAATGA AAGAGGAGGC TGATGAACAA 
CTGCAAAAGG CTAAGGAAGA CATTGAGACA CTACAGATGA AGTATGTGGA ATTGGAGACA 
ACGATCAACA AAGAGGTGTT CTCCAACTCT GAAATTGAAA CTCTGAAGTC GGAACATGAA 
ATTGTTCGTA AACTGATGTT GGATGAAATC CATCGTCTTG AGAATGAAAT GTCTGCTCTT 
CAACCGAAGA ATGATACTAC TGAACTGGAA GAACTTCAGA AGACTCTCGA TGATCTCAAA 
ATTGACTGTT GCAATTTGAC TTCAAAAATG CTTGAACTTC AGTCAGAGCT CGTAGAAGTG 
AAAGAGAAAG CCACGTCAGA AATTGGGGAA GCTGTTCAGA AAAACGGTGA ACTCCTGGAA 
CAGATCAATA GCCTTCGCGT CGAAAATGCA AAATTGGTGG ACATGGAAGG TCAGCTAAAC 
GATGCACATC GTAAAGCGGA AGATAAAGAT GTTCGAATCA GTGAACTATT GACTACCATT 
GAGTCTCTTC GTCAAGATTC TGAGGCCAGC GATAAACTTC TAATGGATTC GGAGTCTACA 
CAAAATGAGT ATTCGCTTGC TCTTGAAAAC ACAGTCTCTG AGTTGGAAAC AATGCGAAGA 
GAATATAAGG CTTCGGTGGA TAAAGTTTGC AGTCTTCAAC TGGAACTAGA AGAAATTCAA 
CATGAAACAT CAGTTGAATT GGAAGAGGCG GAAATAAGAA TTAAAGAATT GGAGTTGGCA 
CAAGAAGAAG CTGTAAAAAC TGGAAGTTCA CAGCTCAAGA AGCTAGAAAT TGTTCAAGAA 
GATTGTCAGA AGCTTCGTGA TCAATTGAAG GAGGAACAAA TTCAGCAACT TGTATCTCTT 
CGCGAGACTT CTGAAGTCAT GCACCAGGAA TCGGCTCGAC ATCAAGAAGA AAAGTACCAG 
ATTCAGAGCA AGTTGATGTC GACGGAAGCA GAAGTTATTG AGCTGAGATC CTCTATTGAT 
TCTCTCCAAG CTGAAGTTCG AGTGCAGTCA GATTCCGCCG CAGACCAAAA ACACATCCTT 
GAAGATTATT TGAGAAAAAT TCGGCAAGCA GAGGAAACCA ACGAAAAACT TCGCTCTGAT 
TTGGCCTCCT CTGAAGAACA AATTCTAGAT CTGAAGAATC AACAGGAATC ATTGATTGAT 
GATTTGAAGG AAAAATTGCA CTCTGCAGAA AGTACGAATC AAGAATTGCA GGTCTCTCTG 
GAGATGCTCA AGATAGAAGT CAGTAATGCT CGTCAGAAAG TGATGGAGAG TGAGGTTTTA 
AAAGAATCTT TCGAAGCCCT TCAACTGGAG TTGTCGGCAT CACAAGAAGT TTCTCGATCA 
GTGGTTGATG CTGCAGTTCA AGAAAAAGAT GGTCTTCTGA GACTGGTGGA TACGCTGAAG 
TTGAAAATTG AAGATACGGA AAAGTCTGCT CAAGATCTTC AACAAAGCTC TGTGGAAGAG 
ATAAAACAAC TTCAATTGGA CCTTCAAAAT TTCAAACAAA ATGCTGAAGT TCTCGAATCT 
CTGAATGAAA AACTAAATTC TAGTCACAAG AGGGATATGG TGGCGTTGGC ATCTCAACTA 
GAAGAGCTTC AACATAAACT CGTCGTCGGA GAATCCCAAG TGGAAAATGT TAAGGAAGAA 
CTGATTGGAG CTAAGATAAT GAACAAGGAA ATGGTTGATG AACTGAATGC GAAGCTTGGG 
GATGCTCTTG AAGGGATGGA AGAACTGAAA AAGAGCCTAG AAGTATCCGA AGCTAAAGTT 
CAGAGAAGAG AAGAAGAGCT AATCGCTCAA GTATCGAAAC ATCGTGATCA GCAGGAGCAG 
CTTCAATTGA CTCTCGACGA GCTCAAATCG GCTCAACATT CCACGGAAAC ATCCCGTTCC 
CAGTCAAATG AACTTGCTGC TCGTATCGAA GAGCTTGAAG CTTCCATCTC CTTTGCACAG 
AAGGCTCTTC AAGATGTAGA AGACGTCAAA CATCAACAAG ACATTCAGAT ATCTGAGGCG 
AATGAGGCAA TGGTAAAGCT GAAGCAAGAC TTTGAGACAG AGAGGACATC ACTTCAAAAC 
GAGTTCAACC AAACTGTTTC CGCAGACAAA GAGCAGCTTG GTCATGCTGA ACAAATGATT 
GCTCAGAAAG AAAAAGAGAT TATCACTCTC CAAGCTCGAA TCGAAGCGAT GTCTCAGCAG 
TTCGAGGAGC GCCTTGAAGC ATCGAATGTT TGGAAGACCC AAGCCATGAA TGTCGGTACA 
CTGACTGAAT CGTTGTCTCA GTTACAAGTA CAACTTCAAC AAATGAATGA GAAGCTGGTT 
GCATCGGACA AATACGCAGT TGAAGTGGAG CAGCAAGCTC AGCATGATAT AACTGTGATC 
CAGGAAGAGA AGAACGAGCA ATCAGCGGCT CTAGAAGAAG CACTATCCAA AATAGCGGAA 
CTTGAGGAGC AACTGGGAAG AGCCCAGAAG GAGATTGTAC GACTCGAGAA GGTGTGTGAC 
GATTTCGACG ACGTTGAACG AGAGCTGAAG GATGCCATCT CGAAGCTTCA ATCTGAGATA 
AAGCAATTGA AAGGAATCAA GAAACCACCA AAAGTAATGG GACTCCTTCA ACAGGCCAGA 
CTTGGAGTGA AGCCGCTGAG TCGTGAACAT TCTCATGCGG AGCCACCAGA GCCTGTTGTT 
GAGGACAAGT TCGAAGATGC TCAGGATTCG TTCCAAGAAG AGTTTTCCCA TTCGCCAGAT 
GCTATCACGT CATCTACGGT ACTCCATCCA GATGATCATC TTCAAGAAAC AACTGCAGTT 
GAAACGCCGT CGAAGAAGGC GAACCGCTCA AACTGCAACC AGCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_505489.1
CDS	1..3888
Translation	MEESTNDGDENKPATGKKRQQLESPFSAATPKSRLGKESKRFFGRSAMNLADGNLEETRIEPDSRHSSTSTSDSILDDSSISNFSTLAPPNTSVDDNSVCEPPRASSAHDVDPNLEQTKVYSEDSISKDCSIADESFATDGDVTLANDFFQQATIQDLENTPSTPLRSQTQVGDESTPTAPSPLRSKIPIESEVVQSTSVESVQSTSQHEKSRIEYSLYEFEMLEKNIEHDEVVKDLQLKIELLGEKHRQTLVEIKEAREVEEKMLMQQVEEAVKKTKSEREAAKTLEQLLEKRIEELEMKLTEPNGEKLQFEHQLEELKSRCEELTDKALKVDVMQHSIEDYEKKFVELQEMKEEADEQLQKAKEDIETLQMKYVELETTINKEVFSNSEIETLKSEHEIVRKLMLDEIHRLENEMSALQPKNDTTELEELQKTLDDLKIDCCNLTSKMLELQSELVEVKEKATSEIGEAVQKNGELLEQINSLRVENAKLVDMEGQLNDAHRKAEDKDVRISELLTTIESLRQDSEASDKLLMDSESTQNEYSLALENTVSELETMRREYKASVDKVCSLQLELEEIQHETSVELEEAEIRIKELELAQEEAVKTGSSQLKKLEIVQEDCQKLRDQLKEEQIQQLVSLRETSEVMHQESARHQEEKYQIQSKLMSTEAEVIELRSSIDSLQAEVRVQSDSAADQKHILEDYLRKIRQAEETNEKLRSDLASSEEQILDLKNQQESLIDDLKEKLHSAESTNQELQVSLEMLKIEVSNARQKVMESEVLKESFEALQLELSASQEVSRSVVDAAVQEKDGLLRLVDTLKLKIEDTEKSAQDLQQSSVEEIKQLQLDLQNFKQNAEVLESLNEKLNSSHKRDMVALASQLEELQHKLVVGESQVENVKEELIGAKIMNKEMVDELNAKLGDALEGMEELKKSLEVSEAKVQRREEELIAQVSKHRDQQEQLQLTLDELKSAQHSTETSRSQSNELAARIEELEASISFAQKALQDVEDVKHQQDIQISEANEAMVKLKQDFETERTSLQNEFNQTVSADKEQLGHAEQMIAQKEKEIITLQARIEAMSQQFEERLEASNVWKTQAMNVGTLTESLSQLQVQLQQMNEKLVASDKYAVEVEQQAQHDITVIQEEKNEQSAALEEALSKIAELEEQLGRAQKEIVRLEKVCDDFDDVERELKDAISKLQSEIKQLKGIKKPPKVMGLLQQARLGVKPLSREHSHAEPPEPVVEDKFEDAQDSFQEEFSHSPDAITSSTVLHPDDHLQETTAVETPSKKANRSNCNQQ

Target ORF information:

RefSeq Version	NM_073088.3
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans HoloCentric chromosome binding Protein (hcp-2), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_073088.3

ORF Insert Sequence:

ATGGAGGAAA GTACAAACGA CGGCGATGAA AACAAGCCTG CAACTGGGAA GAAGCGACAA 
CAGCTTGAAT CTCCGTTTTC TGCTGCGACA CCGAAATCGC GTCTCGGAAA GGAATCGAAA 
AGGTTTTTCG GGCGTTCTGC TATGAATTTG GCCGATGGAA ATCTTGAAGA AACTCGCATT 
GAGCCAGACT CGCGCCATTC GTCTACCAGT ACCTCCGACT CTATTCTTGA TGATTCTTCA 
ATCTCCAATT TTTCCACACT CGCCCCGCCA AATACCTCCG TTGATGATAA CAGTGTCTGT 
GAACCGCCAA GAGCTTCCTC AGCTCATGAT GTCGATCCTA ATTTGGAACA AACGAAGGTT 
TACAGTGAAG ACAGCATCAG CAAAGACTGT AGCATTGCTG ACGAGAGTTT TGCGACTGAT 
GGTGACGTCA CACTGGCGAA CGACTTCTTC CAACAAGCAA CGATTCAAGA TCTAGAGAAT 
ACTCCGTCAA CACCACTTCG GAGCCAGACA CAAGTTGGAG ACGAAAGTAC ACCAACTGCT 
CCTTCCCCAC TTCGTTCGAA AATTCCAATC GAGAGTGAGG TTGTGCAGTC AACTTCTGTA 
GAGTCAGTTC AGTCAACATC TCAGCATGAA AAATCGAGAA TTGAATATTC TTTATATGAA 
TTCGAAATGC TGGAGAAAAA TATCGAGCAT GATGAAGTCG TTAAAGATCT TCAATTGAAA 
ATTGAACTTC TTGGAGAGAA ACATAGACAA ACTCTTGTTG AAATTAAAGA AGCTCGTGAA 
GTTGAAGAGA AAATGCTCAT GCAACAAGTG GAGGAGGCTG TAAAAAAGAC GAAATCTGAG 
CGCGAAGCTG CAAAAACTCT GGAACAACTT CTTGAGAAAC GGATTGAAGA GCTCGAGATG 
AAATTAACGG AGCCGAACGG AGAGAAACTA CAGTTTGAAC ATCAGTTGGA AGAGTTGAAG 
AGTCGTTGTG AAGAGCTTAC TGACAAAGCA CTGAAGGTTG ATGTCATGCA ACACAGCATT 
GAGGACTACG AAAAAAAGTT TGTGGAGTTG CAAGAAATGA AAGAGGAGGC TGATGAACAA 
CTGCAAAAGG CTAAGGAAGA CATTGAGACA CTACAGATGA AGTATGTGGA ATTGGAGACA 
ACGATCAACA AAGAGGTGTT CTCCAACTCT GAAATTGAAA CTCTGAAGTC GGAACATGAA 
ATTGTTCGTA AACTGATGTT GGATGAAATC CATCGTCTTG AGAATGAAAT GTCTGCTCTT 
CAACCGAAGA ATGATACTAC TGAACTGGAA GAACTTCAGA AGACTCTCGA TGATCTCAAA 
ATTGACTGTT GCAATTTGAC TTCAAAAATG CTTGAACTTC AGTCAGAGCT CGTAGAAGTG 
AAAGAGAAAG CCACGTCAGA AATTGGGGAA GCTGTTCAGA AAAACGGTGA ACTCCTGGAA 
CAGATCAATA GCCTTCGCGT CGAAAATGCA AAATTGGTGG ACATGGAAGG TCAGCTAAAC 
GATGCACATC GTAAAGCGGA AGATAAAGAT GTTCGAATCA GTGAACTATT GACTACCATT 
GAGTCTCTTC GTCAAGATTC TGAGGCCAGC GATAAACTTC TAATGGATTC GGAGTCTACA 
CAAAATGAGT ATTCGCTTGC TCTTGAAAAC ACAGTCTCTG AGTTGGAAAC AATGCGAAGA 
GAATATAAGG CTTCGGTGGA TAAAGTTTGC AGTCTTCAAC TGGAACTAGA AGAAATTCAA 
CATGAAACAT CAGTTGAATT GGAAGAGGCG GAAATAAGAA TTAAAGAATT GGAGTTGGCA 
CAAGAAGAAG CTGTAAAAAC TGGAAGTTCA CAGCTCAAGA AGCTAGAAAT TGTTCAAGAA 
GATTGTCAGA AGCTTCGTGA TCAATTGAAG GAGGAACAAA TTCAGCAACT TGTATCTCTT 
CGCGAGACTT CTGAAGTCAT GCACCAGGAA TCGGCTCGAC ATCAAGAAGA AAAGTACCAG 
ATTCAGAGCA AGTTGATGTC GACGGAAGCA GAAGTTATTG AGCTGAGATC CTCTATTGAT 
TCTCTCCAAG CTGAAGTTCG AGTGCAGTCA GATTCCGCCG CAGACCAAAA ACACATCCTT 
GAAGATTATT TGAGAAAAAT TCGGCAAGCA GAGGAAACCA ACGAAAAACT TCGCTCTGAT 
TTGGCCTCCT CTGAAGAACA AATTCTAGAT CTGAAGAATC AACAGGAATC ATTGATTGAT 
GATTTGAAGG AAAAATTGCA CTCTGCAGAA AGTACGAATC AAGAATTGCA GGTCTCTCTG 
GAGATGCTCA AGATAGAAGT CAGTAATGCT CGTCAGAAAG TGATGGAGAG TGAGGTTTTA 
AAAGAATCTT TCGAAGCCCT TCAACTGGAG TTGTCGGCAT CACAAGAAGT TTCTCGATCA 
GTGGTTGATG CTGCAGTTCA AGAAAAAGAT GGTCTTCTGA GACTGGTGGA TACGCTGAAG 
TTGAAAATTG AAGATACGGA AAAGTCTGCT CAAGATCTTC AACAAAGCTC TGTGGAAGAG 
ATAAAACAAC TTCAATTGGA CCTTCAAAAT TTCAAACAAA ATGCTGAAGT TCTCGAATCT 
CTGAATGAAA AACTAAATTC TAGTCACAAG AGGGATATGG TGGCGTTGGC ATCTCAACTA 
GAAGAGCTTC AACATAAACT CGTCGTCGGA GAATCCCAAG TGGAAAATGT TAAGGAAGAA 
CTGATTGGAG CTAAGATAAT GAACAAGGAA ATGGTTGATG AACTGAATGC GAAGCTTGGG 
GATGCTCTTG AAGGGATGGA AGAACTGAAA AAGAGCCTAG AAGTATCCGA AGCTAAAGTT 
CAGAGAAGAG AAGAAGAGCT AATCGCTCAA GTATCGAAAC ATCGTGATCA GCAGGAGCAG 
CTTCAATTGA CTCTCGACGA GCTCAAATCG GCTCAACATT CCACGGAAAC ATCCCGTTCC 
CAGTCAAATG AACTTGCTGC TCGTATCGAA GAGCTTGAAG CTTCCATCTC CTTTGCACAG 
AAGGCTCTTC AAGATGTAGA AGACGTCAAA CATCAACAAG ACATTCAGAT ATCTGAGGCG 
AATGAGGCAA TGGTAAAGCT GAAGCAAGAC TTTGAGACAG AGAGGACATC ACTTCAAAAC 
GAGTTCAACC AAACTGTTTC CGCAGACAAA GAGCAGCTTG GTCATGCTGA ACAAATGATT 
GCTCAGAAAG AAAAAGAGAT TATCACTCTC CAAGCTCGAA TCGAAGCGAT GTCTCAGCAG 
TTCGAGGAGC GCCTTGAAGC ATCGAATGTT TGGAAGACCC AAGCCATGAA TGTCGGTACA 
CTGACTGAAT CGTTGTCTCA GTTACAAGTA CAACTTCAAC AAATGAATGA GAAGCTGGTT 
GCATCGGACA AATACGCAGT TGAAGTGGAG CAGCAAGCTC AGCATGATAT AACTGTGATC 
CAGGAAGAGA AGAACGAGCA ATCAGCGGCT CTAGAAGAAG CACTATCCAA AATAGCGGAA 
CTTGAGGAGC AACTGGGAAG AGCCCAGAAG GAGATTGTAC GACTCGAGAA GGTGTGTGAC 
GATTTCGACG ACGTTGAACG AGAGCTGAAG GATGCCATCT CGAAGCTTCA ATCTGAGATA 
AAGCAATTGA AAGGAATCAA GAAACCACCA AAAGTAATGG GACTCCTTCA ACAGGCCAGA 
CTTGGAGTGA AGCCGCTGAG TCGTGAACAT TCTCATGCGG AGCCACCAGA GCCTGTTGTT 
GAGGACAAGT TCGAAGATGC TCAGGATTCG TTCCAAGAAG AGTTTTCCCA TTCGCCAGAT 
GCTATCACGT CATCTACGGT ACTCCATCCA GATGATCATC TTCAAGAAAC AACTGCAGTT 
GAAACGCCGT CGAAGAAGGC GAACCGCTCA AACTGCAACC AGCAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

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hcp-2 cDNA ORF clone, Caenorhabditis elegans

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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