Gene Symbol | spas-1 |
Entrez Gene ID | 179300 |
Full Name | Probable spastin homolog spas-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » spas-1 cDNA ORF clone
Gene Symbol | spas-1 |
Entrez Gene ID | 179300 |
Full Name | Probable spastin homolog spas-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_171501.4 | NP_741586.1 | Probable spastin homolog spas-1 |
NM_001269186.2 | NP_001256115.1 | AAA domain-containing protein |
NM_171501.5 | NP_741586.1 | Probable spastin homolog spas-1 |
NM_001269186.1 | NP_001256115.1 | Probable spastin homolog spas-1 |
Homo sapiens (human) | SPAST | NP_055761.2 |
Oryza sativa (rice) | Os06g0130000 | NP_001056686.1 |
Xenopus tropicalis (tropical clawed frog) | spast | NP_001016453.1 |
SPAST | XP_002799248.1 | |
Canis lupus familiaris (dog) | SPAST | XP_850973.1 |
Drosophila melanogaster (fruit fly) | spas | NP_651206.3 |
Pan troglodytes (chimpanzee) | SPAST | XP_001164367.1 |
Mus musculus (house mouse) | Spast | NP_001156342.1 |
Rattus norvegicus (Norway rat) | Spast | NP_001102172.2 |
Danio rerio (zebrafish) | spast | NP_998080.1 |
Arabidopsis thaliana (thale cress) | AT2G45500 | NP_182074.4 |
Bos taurus (cattle) | SPAST | NP_001075060.1 |
Gallus gallus (chicken) | SPAST | NP_001026232.1 |
Anopheles gambiae (African malaria mosquito) | SPAST_ANOGA | XP_312634.5 |
Caenorhabditis elegans (roundworm) | spas-1 | NP_741586.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The C-terminal alpha-helix of SPAS-1, a Caenorhabditis elegans spastin homologue, is crucial for microtubule severing.
Title: The C-terminal ?-helix of SPAS-1, a Caenorhabditis elegans spastin homologue, is crucial for microtubule severing.
We propose that microtubule binding domain (MTBD) of SPAS-1 plays a critical role in enrichment of SPAS-1 to microtubules, where SPAS-1 is concentrated and able to form a stable hexamer, subsequently its ATPase activity is stimulated.
Title: Conserved aromatic and basic amino acid residues in the pore region of Caenorhabditis elegans spastin play critical roles in microtubule severing.
The following spas-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the spas-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa346685 | |
Clone ID Related Accession (Same CDS sequence) | NM_171501.4 , NM_171501.5 | |
Accession Version | NM_171501.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Probable spastin homolog spas-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_171501.3. COMPLETENESS: incomplete on both ends. |
1 | ATGTTCGCCT TTTCAAAAGG TCCCGCCGGC AGCTCAACTT ACGACAGAGT TGCTCAAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_741586.1 |
CDS | 1..1356 |
Translation |
Target ORF information:
Target ORF information:
|
NM_171501.4 |
1 | ATGTTCGCCT TTTCAAAAGG TCCCGCCGGC AGCTCAACTT ACGACAGAGT TGCTCAAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa346685 | |
Clone ID Related Accession (Same CDS sequence) | NM_171501.4 , NM_171501.5 | |
Accession Version | NM_171501.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Probable spastin homolog spas-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_171501.4. |
1 | ATGTTCGCCT TTTCAAAAGG TCCCGCCGGC AGCTCAACTT ACGACAGAGT TGCTCAAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_741586.1 |
CDS | 6..1361 |
Translation |
Target ORF information:
Target ORF information:
|
NM_171501.5 |
1 | ATGTTCGCCT TTTCAAAAGG TCCCGCCGGC AGCTCAACTT ACGACAGAGT TGCTCAAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa346688 | |
Clone ID Related Accession (Same CDS sequence) | NM_001269186.2 , NM_001269186.1 | |
Accession Version | NM_001269186.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1539bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | AAA domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_001269186.1. |
1 | ATGTTCGCCT TTTCAAAAGG TCCCGCCGGC AGCTCAACTT ACGACAGAGT TGCTCAAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001256115.1 |
CDS | 6..1544 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001269186.2 |
1 | ATGTTCGCCT TTTCAAAAGG TCCCGCCGGC AGCTCAACTT ACGACAGAGT TGCTCAAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa346688 | |
Clone ID Related Accession (Same CDS sequence) | NM_001269186.2 , NM_001269186.1 | |
Accession Version | NM_001269186.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1539bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Probable spastin homolog spas-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). COMPLETENESS: incomplete on both ends. |
1 | ATGTTCGCCT TTTCAAAAGG TCCCGCCGGC AGCTCAACTT ACGACAGAGT TGCTCAAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001256115.1 |
CDS | 1..1539 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001269186.1 |
1 | ATGTTCGCCT TTTCAAAAGG TCCCGCCGGC AGCTCAACTT ACGACAGAGT TGCTCAAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |