Gene Symbol | dnc-1 |
Entrez Gene ID | 177987 |
Full Name | DyNactin Complex component |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » dnc-1 cDNA ORF clone
Gene Symbol | dnc-1 |
Entrez Gene ID | 177987 |
Full Name | DyNactin Complex component |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001268592.1 | NP_001255521.1 | DyNactin Complex component |
NM_001276853.1 | NP_001263782.1 | DyNactin Complex component |
NM_001268592.2 | NP_001255521.1 | CAP-Gly domain-containing protein |
NM_001268591.1 | NP_001255520.1 | DyNactin Complex component |
NM_001276852.1 | NP_001263781.1 | DyNactin Complex component |
NM_001276852.2 | NP_001263781.1 | CAP-Gly domain-containing protein |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
we dissect the role of dynactin's microtubule binding activity, located in the p150 CAP-Gly domain and an adjacent basic patch, in the C. elegans zygote. Our results suggest that p150 GAP-Gly domain binding to microtubules promotes initiation of dynein-mediated organelle transport in the dividing one-cell embryo, and that this function of p150 is critical for generating cytoplasmic pulling forces for centrosome
Title: Dynactin binding to tyrosinated microtubules promotes centrosome centration in C. elegans by enhancing dynein-mediated organelle transport.
results suggest that decreased expression of dynactin 1 induces motor neuron degeneration and that the transport of autophagosomes is a novel and substantial therapeutic target for motor neuron degeneration
Title: dnc-1/dynactin 1 knockdown disrupts transport of autophagosomes and induces motor neuron degeneration.
putative UNC-104 interactors, namely UNC-16(JIP3), DNC-1(DCTN1/Glued) and SYD-2(Liprin-alpha), inherit different functions in steering UNC-104 to specific sub-cellular locations in the neuron
Title: Sub-cellular distribution of UNC-104(KIF1A) upon binding to adaptors as UNC-16(JIP3), DNC-1(DCTN1/Glued) and SYD-2(Liprin-?) in C. elegans neurons.
Src and Wnt signaling regulate dynactin accumulation to the P2-EMS cell border in C. elegans embryos
Title: Src and Wnt signaling regulate dynactin accumulation to the P2-EMS cell border in C. elegans embryos.
The following dnc-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the dnc-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa342280 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268591.1 | |
Accession Version | NM_001268591.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3981bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | DyNactin Complex component | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGTCGTTCG AAATAGGAAC TCGGGTAAAA ACAAGCTCGG GAAATGGAAG AGTCGTGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001255520.1 |
CDS | 1..3981 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268591.1 |
1 | ATGTCGTTCG AAATAGGAAC TCGGGTAAAA ACAAGCTCGG GAAATGGAAG AGTCGTGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa342866 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268592.1 , NM_001268592.2 | |
Accession Version | NM_001268592.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4056bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | DyNactin Complex component | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGTCGTTCG AAATAGGAAC TCGGGTAAAA ACAAGCTCGG GAAATGGAAG AGTCGTGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001255521.1 |
CDS | 1..4056 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268592.1 |
1 | ATGTCGTTCG AAATAGGAAC TCGGGTAAAA ACAAGCTCGG GAAATGGAAG AGTCGTGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa342866 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268592.1 , NM_001268592.2 | |
Accession Version | NM_001268592.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4056bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | CAP-Gly domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001268592.1. |
1 | ATGTCGTTCG AAATAGGAAC TCGGGTAAAA ACAAGCTCGG GAAATGGAAG AGTCGTGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001255521.1 |
CDS | 84..4139 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268592.2 |
1 | ATGTCGTTCG AAATAGGAAC TCGGGTAAAA ACAAGCTCGG GAAATGGAAG AGTCGTGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa342883 | |
Clone ID Related Accession (Same CDS sequence) | NM_001276853.1 | |
Accession Version | NM_001276853.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3972bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | DyNactin Complex component | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGTCGTTCG AAATAGGAAC TCGGGTAAAA ACAAGCTCGG GAAATGGAAG AGTCGTGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001263782.1 |
CDS | 1..3972 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001276853.1 |
1 | ATGTCGTTCG AAATAGGAAC TCGGGTAAAA ACAAGCTCGG GAAATGGAAG AGTCGTGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa342884 | |
Clone ID Related Accession (Same CDS sequence) | NM_001276852.1 , NM_001276852.2 | |
Accession Version | NM_001276852.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3897bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | DyNactin Complex component | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGTCGTTCG AAATAGGAAC TCGGGTAAAA ACAAGCTCGG GAAATGGAAG AGTCGTGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001263781.1 |
CDS | 1..3897 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001276852.1 |
1 | ATGTCGTTCG AAATAGGAAC TCGGGTAAAA ACAAGCTCGG GAAATGGAAG AGTCGTGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa342884 | |
Clone ID Related Accession (Same CDS sequence) | NM_001276852.1 , NM_001276852.2 | |
Accession Version | NM_001276852.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3897bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | CAP-Gly domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001276852.1. |
1 | ATGTCGTTCG AAATAGGAAC TCGGGTAAAA ACAAGCTCGG GAAATGGAAG AGTCGTGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001263781.1 |
CDS | 56..3952 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001276852.2 |
1 | ATGTCGTTCG AAATAGGAAC TCGGGTAAAA ACAAGCTCGG GAAATGGAAG AGTCGTGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |