Gene Symbol | nhr-8 |
Entrez Gene ID | 177551 |
Full Name | Nuclear hormone receptor family member nhr-8 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » nhr-8 cDNA ORF clone
Gene Symbol | nhr-8 |
Entrez Gene ID | 177551 |
Full Name | Nuclear hormone receptor family member nhr-8 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001027998.6 | NP_001023169.1 | Nuclear hormone receptor family member nhr-8 |
NM_171382.3 | NP_741445.1 | Nuclear hormone receptor family member nhr-8 |
NM_001027998.5 | NP_001023169.1 | Nuclear hormone receptor family member nhr-8 |
NM_171382.4 | NP_741445.1 | Nuclear hormone receptor family member nhr-8 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Pdda is abolished by synthetic ascarosides and steroidal ligands of the nuclear hormone receptor DAF-12. We show that neither ascarosides nor any known steroid hormones are required for Pdda and that another chemical signal mediates this phenotype, in part via the nuclear hormone receptor NHR-8.
Title: Larval crowding accelerates C. elegans development and reduces lifespan.
Dafachronic acid signaling through NHR-8 is essential for diet restriction-mediated longevity.
Title: Steroid hormone signalling links reproduction to lifespan in dietary-restricted Caenorhabditis elegans.
Knockdown of the NHR-8 nuclear receptor enhanced sensitivity to the lipid-reducing activity of alkaloids in Caenorhabditis elegans.
Title: Knockdown of the NHR-8 nuclear receptor enhanced sensitivity to the lipid-reducing activity of alkaloids in Caenorhabditis elegans.
C. elegans NHR-8 NR, a homolog of vertebrate liver X and vitamin D receptors, regulates nematode cholesterol balance, fatty acid desaturation, apolipoprotein production, and bile acid metabolism.
Title: The NHR-8 nuclear receptor regulates cholesterol and bile acid homeostasis in C. elegans.
The following nhr-8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the nhr-8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa343472 | |
Clone ID Related Accession (Same CDS sequence) | NM_171382.3 , NM_171382.4 | |
Accession Version | NM_171382.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1683bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-8 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 27, 2008 this sequence version replaced NM_171382.2. COMPLETENESS: incomplete on both ends. |
1 | ATGCCTTCGT CTTCTCCATC GATGGACGAG TCTCGAAGGT CTGCTGTTCC ACCAAAAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_741445.1 |
CDS | 1..1683 |
Translation |
Target ORF information:
Target ORF information:
|
NM_171382.3 |
1 | ATGCCTTCGT CTTCTCCATC GATGGACGAG TCTCGAAGGT CTGCTGTTCC ACCAAAAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343472 | |
Clone ID Related Accession (Same CDS sequence) | NM_171382.3 , NM_171382.4 | |
Accession Version | NM_171382.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1683bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-8 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_171382.3. |
1 | ATGCCTTCGT CTTCTCCATC GATGGACGAG TCTCGAAGGT CTGCTGTTCC ACCAAAAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_741445.1 |
CDS | 175..1857 |
Translation |
Target ORF information:
Target ORF information:
|
NM_171382.4 |
1 | ATGCCTTCGT CTTCTCCATC GATGGACGAG TCTCGAAGGT CTGCTGTTCC ACCAAAAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343473 | |
Clone ID Related Accession (Same CDS sequence) | NM_001027998.6 , NM_001027998.5 | |
Accession Version | NM_001027998.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-8 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001027998.5. |
1 | ATGCCTTCGT CTTCTCCATC GATGGACGAG TCTCGAAGGT CTGCTGTTCC ACCAAAAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001023169.1 |
CDS | 162..1841 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001027998.6 |
1 | ATGCCTTCGT CTTCTCCATC GATGGACGAG TCTCGAAGGT CTGCTGTTCC ACCAAAAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343473 | |
Clone ID Related Accession (Same CDS sequence) | NM_001027998.6 , NM_001027998.5 | |
Accession Version | NM_001027998.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-8 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_001027998.4. COMPLETENESS: incomplete on both ends. |
1 | ATGCCTTCGT CTTCTCCATC GATGGACGAG TCTCGAAGGT CTGCTGTTCC ACCAAAAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001023169.1 |
CDS | 1..1680 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001027998.5 |
1 | ATGCCTTCGT CTTCTCCATC GATGGACGAG TCTCGAAGGT CTGCTGTTCC ACCAAAAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |