Gene Symbol | pnc-1 |
Entrez Gene ID | 176833 |
Full Name | Pyrazinamidase and NiCotinamidase |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » pnc-1 cDNA ORF clone
Gene Symbol | pnc-1 |
Entrez Gene ID | 176833 |
Full Name | Pyrazinamidase and NiCotinamidase |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_067475.4 | NP_499876.1 | Isochorismatase domain-containing protein |
NM_067475.3 | NP_499876.1 | Pyrazinamidase and NiCotinamidase |
NM_001129336.3 | NP_001122808.1 | Isochorismatase domain-containing protein |
NM_001129336.2 | NP_001122808.1 | Pyrazinamidase and NiCotinamidase |
Caenorhabditis elegans (roundworm) | pnc-1 | NP_499876.1 |
Saccharomyces cerevisiae (baker's yeast) | PNC1 | NP_011478.3 |
Schizosaccharomyces pombe (fission yeast) | pnc1 | NP_596029.2 |
Neurospora crassa | NCU00713 | XP_964547.1 |
Eremothecium gossypii | AGOS_AFR466C | NP_986013.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_08976 | XP_003714015.1 |
Caenorhabditis elegans (roundworm) | pnc-2 | NP_001023531.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP001435 | XP_321695.5 |
Kluyveromyces lactis | KLLA0F22242g | XP_456073.1 |
Drosophila melanogaster (fruit fly) | Naam | NP_001262738.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Mutations in the nicotinamidase PNC-1 cause developmental and functional defects in the reproductive system; the development of the gonad is delayed, four uterine cells die by necrosis and the mutant animals are egg-laying defective.
Title: Nicotinamidase modulation of NAD+ biosynthesis and nicotinamide levels separately affect reproductive development and cell survival in C. elegans.
Increased gene dosage of pnc-1 (nicotinamide phosphoribosyltransferase) increases adult survival under conditions of oxidative stress.
Title: The Caenorhabditis elegans nicotinamidase PNC-1 enhances survival.
The following pnc-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pnc-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa343883 | |
Clone ID Related Accession (Same CDS sequence) | NM_067475.4 , NM_067475.3 | |
Accession Version | NM_067475.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Isochorismatase domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_067475.3. |
1 | ATGTTTCCCT GCCCAAAGCT TATATTCCCA CGTTTAATGG CATTTATTGG GCTCATTTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499876.1 |
CDS | 167..1174 |
Translation |
Target ORF information:
Target ORF information:
|
NM_067475.4 |
1 | ATGTTTCCCT GCCCAAAGCT TATATTCCCA CGTTTAATGG CATTTATTGG GCTCATTTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343883 | |
Clone ID Related Accession (Same CDS sequence) | NM_067475.4 , NM_067475.3 | |
Accession Version | NM_067475.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Pyrazinamidase and NiCotinamidase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_067475.2. COMPLETENESS: incomplete on both ends. |
1 | ATGTTTCCCT GCCCAAAGCT TATATTCCCA CGTTTAATGG CATTTATTGG GCTCATTTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499876.1 |
CDS | 1..1008 |
Translation |
Target ORF information:
Target ORF information:
|
NM_067475.3 |
1 | ATGTTTCCCT GCCCAAAGCT TATATTCCCA CGTTTAATGG CATTTATTGG GCTCATTTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343890 | |
Clone ID Related Accession (Same CDS sequence) | NM_001129336.3 , NM_001129336.2 | |
Accession Version | NM_001129336.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Isochorismatase domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001129336.2. COMPLETENESS: incomplete on the 5' end. |
1 | ATGGTACACT CAGACAATTC GGCAACAACC AATAATAACA CAATTCTCGG CAACCAATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001122808.1 |
CDS | 1..948 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001129336.3 |
1 | ATGGTACACT CAGACAATTC GGCAACAACC AATAATAACA CAATTCTCGG CAACCAATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343890 | |
Clone ID Related Accession (Same CDS sequence) | NM_001129336.3 , NM_001129336.2 | |
Accession Version | NM_001129336.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Pyrazinamidase and NiCotinamidase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_001129336.1. COMPLETENESS: incomplete on both ends. |
1 | ATGGTACACT CAGACAATTC GGCAACAACC AATAATAACA CAATTCTCGG CAACCAATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001122808.1 |
CDS | 1..948 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001129336.2 |
1 | ATGGTACACT CAGACAATTC GGCAACAACC AATAATAACA CAATTCTCGG CAACCAATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |