Gene Symbol | pdr-1 |
Entrez Gene ID | 176816 |
Full Name | E3 ubiquitin-protein ligase parkin |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » pdr-1 cDNA ORF clone
Gene Symbol | pdr-1 |
Entrez Gene ID | 176816 |
Full Name | E3 ubiquitin-protein ligase parkin |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001306674.2 | NP_001293603.1 | RBR-type E3 ubiquitin transferase |
NM_001306674.1 | NP_001293603.1 | RBR-type E3 ubiquitin transferase |
NM_001306673.1 | NP_001293602.1 | Parkinson's Disease Related |
NM_067445.6 | NP_499846.2 | E3 ubiquitin-protein ligase parkin |
NM_067445.7 | NP_499846.2 | E3 ubiquitin-protein ligase parkin |
NM_001372678.1 | NP_001360308.1 | Ubiquitin-like domain-containing protein |
LOC710899 | XP_001099588.2 | |
Canis lupus familiaris (dog) | PARK2 | XP_855152.2 |
Caenorhabditis elegans (roundworm) | pdr-1 | NP_499846.2 |
Mus musculus (house mouse) | Park2 | NP_057903.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP006580 | XP_316606.2 |
Homo sapiens (human) | PARK2 | NP_004553.2 |
Danio rerio (zebrafish) | park2 | NP_001017635.1 |
Pan troglodytes (chimpanzee) | PARK2 | XP_001153913.1 |
Rattus norvegicus (Norway rat) | Park2 | NP_064478.1 |
Gallus gallus (chicken) | PARK2 | XP_004935613.1 |
Drosophila melanogaster (fruit fly) | park | NP_730601.1 |
Bos taurus (cattle) | PARK2 | NP_001185994.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
While no change in mRNA expression of the major Mn importer proteins (smf-1-3) was found in pdr-1 mutants, significant downregulation in mRNA levels of the putative Mn exporter ferroportin (fpn-1.1) was observed.
Title: Loss of pdr-1/parkin influences Mn homeostasis through altered ferroportin expression in C. elegans.
These data show that mutation in the Caenorhabditis elegans orthologue of Parkin (pdr-1) modulates the level of a large heteroplasmic mtDNA truncation.
Title: Parkin modulates heteroplasmy of truncated mtDNA in Caenorhabditis elegans.
The pdr1 and djr1.1 mutants showed enhanced Mn accumulation and oxidative stress that was reduced by alpha-synuclein.
Title: The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of ?-synuclein in C. elegans.
PDR-1 inhibits apoptotic cell engulfment and distal tip cell migration by ubiquitylating CED-10 for degradation.
Title: PDR-1/hParkin negatively regulates the phagocytosis of apoptotic cell corpses in Caenorhabditis elegans.
PD-related genetic modifications of alpha-synuclein, parkin, and DJ-1 disrupt the mitochondrial function in C. elegans [K08E3.7 is parkin]
Title: Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.
The following pdr-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pdr-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa340286 | |
Clone ID Related Accession (Same CDS sequence) | NM_067445.6 , NM_067445.7 | |
Accession Version | NM_067445.6 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1161bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | E3 ubiquitin-protein ligase parkin | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_067445.5. COMPLETENESS: incomplete on both ends. |
1 | ATGTCTGATG AAATCTCTAT ATTAATACAA GATAGAAAAA CAGGTCAACG TAGGAATCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499846.2 |
CDS | 1..1161 |
Translation |
Target ORF information:
Target ORF information:
|
NM_067445.6 |
1 | ATGTCTGATG AAATCTCTAT ATTAATACAA GATAGAAAAA CAGGTCAACG TAGGAATCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340286 | |
Clone ID Related Accession (Same CDS sequence) | NM_067445.6 , NM_067445.7 | |
Accession Version | NM_067445.7 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1161bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | E3 ubiquitin-protein ligase parkin | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_067445.6. |
1 | ATGTCTGATG AAATCTCTAT ATTAATACAA GATAGAAAAA CAGGTCAACG TAGGAATCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499846.2 |
CDS | 13..1173 |
Translation |
Target ORF information:
Target ORF information:
|
NM_067445.7 |
1 | ATGTCTGATG AAATCTCTAT ATTAATACAA GATAGAAAAA CAGGTCAACG TAGGAATCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340391 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306673.1 , NM_001372678.1 | |
Accession Version | NM_001306673.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Parkinson's Disease Related | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). COMPLETENESS: incomplete on both ends. |
1 | ATGTCTGATG AAATCTCTAT ATTAATACAA GATAGAAAAA CAGGTCAACG TAGGAATCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293602.1 |
CDS | 1..732 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306673.1 |
1 | ATGTCTGATG AAATCTCTAT ATTAATACAA GATAGAAAAA CAGGTCAACG TAGGAATCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340391 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306673.1 , NM_001372678.1 | |
Accession Version | NM_001372678.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Ubiquitin-like domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). |
1 | ATGTCTGATG AAATCTCTAT ATTAATACAA GATAGAAAAA CAGGTCAACG TAGGAATCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001360308.1 |
CDS | 13..744 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001372678.1 |
1 | ATGTCTGATG AAATCTCTAT ATTAATACAA GATAGAAAAA CAGGTCAACG TAGGAATCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340392 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306674.2 , NM_001306674.1 | |
Accession Version | NM_001306674.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | RBR-type E3 ubiquitin transferase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001306674.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGAGGGATT TGTCACTGAC ACCTGCAACA CAAATCATGC TTCTCCGTCC AAAGTTCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293603.1 |
CDS | 1..975 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306674.2 |
1 | ATGAGGGATT TGTCACTGAC ACCTGCAACA CAAATCATGC TTCTCCGTCC AAAGTTCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340392 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306674.2 , NM_001306674.1 | |
Accession Version | NM_001306674.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | RBR-type E3 ubiquitin transferase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). COMPLETENESS: incomplete on both ends. |
1 | ATGAGGGATT TGTCACTGAC ACCTGCAACA CAAATCATGC TTCTCCGTCC AAAGTTCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293603.1 |
CDS | 1..975 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306674.1 |
1 | ATGAGGGATT TGTCACTGAC ACCTGCAACA CAAATCATGC TTCTCCGTCC AAAGTTCAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |