Gene Symbol | clk-2 |
Entrez Gene ID | 176065 |
Full Name | Telomere length regulation protein clk-2 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » clk-2 cDNA ORF clone
Gene Symbol | clk-2 |
Entrez Gene ID | 176065 |
Full Name | Telomere length regulation protein clk-2 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_066249.3 | NP_498650.2 | Telomere length regulation protein clk-2 |
NM_066249.4 | NP_498650.2 | Telomere length regulation protein clk-2 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Clk-2 mutants accumulate genomic instability and show a delay of embryonic cell cycle timing.
Title: Functional dissection of Caenorhabditis elegans CLK-2/TEL2 cell cycle defects during embryogenesis and germline development.
DNA damage checkpoint protein clk-2 suppresses the frequency of mutation by ensuring that spontaneous DNA damage is accurately repaired in C. elegans germ cells.
Title: Mutator phenotype of Caenorhabditis elegans DNA damage checkpoint mutants.
Persistent repair intermediates and/or single-stranded DNA formed during repair of misincorporated uracil are tolerated in the absence of the CLK-2 checkpoint in C. elegans.
Title: Abrogation of the CLK-2 checkpoint leads to tolerance to base-excision repair intermediates.
Prolonged life span of Clk mutants cannot be attributed to reduced metabolic rate or an increased activity of the major antioxidant enzymes catalase and SOD.
Title: No reduction of energy metabolism in Clk mutants.
The following clk-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the clk-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa340987 | |
Clone ID Related Accession (Same CDS sequence) | NM_066249.3 , NM_066249.4 | |
Accession Version | NM_066249.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2634bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Telomere length regulation protein clk-2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_066249.2. COMPLETENESS: incomplete on both ends. |
1 | ATGAATTTAC GAAGTCGCCT GGTAAATGCC ACGGAACGTG CTGTGCTTTT TCAAATTTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_498650.2 |
CDS | 1..2634 |
Translation |
Target ORF information:
Target ORF information:
|
NM_066249.3 |
1 | ATGAATTTAC GAAGTCGCCT GGTAAATGCC ACGGAACGTG CTGTGCTTTT TCAAATTTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340987 | |
Clone ID Related Accession (Same CDS sequence) | NM_066249.3 , NM_066249.4 | |
Accession Version | NM_066249.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2634bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Telomere length regulation protein clk-2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_066249.3. COMPLETENESS: incomplete on the 5' end. |
1 | ATGAATTTAC GAAGTCGCCT GGTAAATGCC ACGGAACGTG CTGTGCTTTT TCAAATTTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_498650.2 |
CDS | 1..2634 |
Translation |
Target ORF information:
Target ORF information:
|
NM_066249.4 |
1 | ATGAATTTAC GAAGTCGCCT GGTAAATGCC ACGGAACGTG CTGTGCTTTT TCAAATTTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |