Gene Symbol | prmt-5 |
Entrez Gene ID | 175717 |
Full Name | Protein arginine N-methyltransferase 5 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » prmt-5 cDNA ORF clone
Gene Symbol | prmt-5 |
Entrez Gene ID | 175717 |
Full Name | Protein arginine N-methyltransferase 5 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_065711.6 | NP_498112.1 | Protein arginine N-methyltransferase 5 |
NM_065711.7 | NP_498112.1 | Protein arginine N-methyltransferase 5 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
It show the morphological and functional phenotypes of single or double null alleles of prmt-5 in Caenorhabditis elegans. The prmt-1;prmt-5 double mutants are viable, and exhibit short body length and small brood size compared to N2 and each of the single mutants.
Title: Simultaneous ablation of prmt-1 and prmt-5 abolishes asymmetric and symmetric arginine dimethylations in Caenorhabditis elegans.
The PRMT-5 catalyzes the symmetric dimethylation of substrates containing monomethylarginine residues in vivo.
Title: PRMT-5 converts monomethylarginines into symmetrical dimethylarginines in Caenorhabditis elegans.
Analysis of prmt-5-deficient worms indicated that methylation promoted the dopamine-mediated modulation of chemosensory and locomotory behaviors through the DOP-3 receptor.
Title: The protein arginine methyltransferase PRMT5 promotes D2-like dopamine receptor signaling.
data confirm that MEP50 plays a key role in substrate recognition and activates PRMT5 activity by increasing its affinity for protein substrates.
Title: Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion.
the substrate specificity, processivity, and kinetic mechanism of bacterially expressed Caenorhabditis elegans PRMT5 (cPRMT5).
Title: Substrate specificity, processivity, and kinetic mechanism of protein arginine methyltransferase 5.
The following prmt-5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the prmt-5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa341223 | |
Clone ID Related Accession (Same CDS sequence) | NM_065711.6 , NM_065711.7 | |
Accession Version | NM_065711.6 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2205bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Protein arginine N-methyltransferase 5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_065711.5. COMPLETENESS: incomplete on both ends. |
1 | ATGAGTAACA GAACGTATGC CGATAATCTG TTTCCACAAC AGGTCGCGGA GCAGCATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_498112.1 |
CDS | 1..2205 |
Translation |
Target ORF information:
Target ORF information:
|
NM_065711.6 |
1 | ATGAGTAACA GAACGTATGC CGATAATCTG TTTCCACAAC AGGTCGCGGA GCAGCATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341223 | |
Clone ID Related Accession (Same CDS sequence) | NM_065711.6 , NM_065711.7 | |
Accession Version | NM_065711.7 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2205bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Protein arginine N-methyltransferase 5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_065711.6. |
1 | ATGAGTAACA GAACGTATGC CGATAATCTG TTTCCACAAC AGGTCGCGGA GCAGCATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_498112.1 |
CDS | 25..2229 |
Translation |
Target ORF information:
Target ORF information:
|
NM_065711.7 |
1 | ATGAGTAACA GAACGTATGC CGATAATCTG TTTCCACAAC AGGTCGCGGA GCAGCATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |