Gene Symbol | ced-4 |
Entrez Gene ID | 175643 |
Full Name | Cell death protein 4 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » ced-4 cDNA ORF clone
Gene Symbol | ced-4 |
Entrez Gene ID | 175643 |
Full Name | Cell death protein 4 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001026032.1 | NP_001021203.1 | Cell death protein 4 |
NM_001026032.2 | NP_001021203.1 | Cell death protein 4 |
NM_001026031.2 | NP_001021202.1 | Cell death protein 4 |
NM_001026031.3 | NP_001021202.1 | Cell death protein 4 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
A protein interaction cascade involving EGL-1, CED-9, CED-4, and CED-3 results in the activation of the key cell death protease CED-3, which is tightly controlled by multiple positive and negative regulators.
Title: Programmed Cell Death During Caenorhabditis elegans Development.
a working model in which two molecules of CED-3 zymogen, through specific recognition, are forced into the hutch of the CED-4 apoptosome, consequently undergoing dimerization and autocatalytic maturation
Title: Mechanistic insights into CED-4-mediated activation of CED-3.
CED-9 associates with the outer mitochondrial membrane within distinct foci that do not overlap with CED-4
Title: Evidence that CED-9/Bcl2 and CED-4/Apaf-1 localization is not consistent with the current model for C. elegans apoptosis induction.
CED-4 caspase plays a role in axon repair.
Title: The core apoptotic executioner proteins CED-3 and CED-4 promote initiation of neuronal regeneration in Caenorhabditis elegans.
Genetic evidence confirmed that apoptosis induced by loss of ifg-1 p170 mRNA was caspase (ced-3) and apoptosome (ced-4/Apaf-1) dependent.
Title: Cap-independent translation promotes C. elegans germ cell apoptosis through Apaf-1/CED-4 in a caspase-dependent mechanism.
The following ced-4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ced-4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa341243 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026031.2 , NM_001026031.3 | |
Accession Version | NM_001026031.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1650bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Cell death protein 4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_001026031.1. COMPLETENESS: incomplete on both ends. |
1 | ATGCTCTGCG AAATCGAATG CCGCGCTTTG AGCACGGCAC ACACGAGGCT CATCCACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021202.1 |
CDS | 1..1650 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026031.2 |
1 | ATGCTCTGCG AAATCGAATG CCGCGCTTTG AGCACGGCAC ACACGAGGCT CATCCACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341243 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026031.2 , NM_001026031.3 | |
Accession Version | NM_001026031.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1650bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Cell death protein 4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001026031.2. COMPLETENESS: incomplete on the 5' end. |
1 | ATGCTCTGCG AAATCGAATG CCGCGCTTTG AGCACGGCAC ACACGAGGCT CATCCACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021202.1 |
CDS | 1..1650 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026031.3 |
1 | ATGCTCTGCG AAATCGAATG CCGCGCTTTG AGCACGGCAC ACACGAGGCT CATCCACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341244 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026032.1 , NM_001026032.2 | |
Accession Version | NM_001026032.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1716bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Cell death protein 4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). COMPLETENESS: incomplete on both ends. |
1 | ATGCTCTGCG AAATCGAATG CCGCGCTTTG AGCACGGCAC ACACGAGGCT CATCCACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021203.1 |
CDS | 1..1716 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026032.1 |
1 | ATGCTCTGCG AAATCGAATG CCGCGCTTTG AGCACGGCAC ACACGAGGCT CATCCACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341244 | |
Clone ID Related Accession (Same CDS sequence) | NM_001026032.1 , NM_001026032.2 | |
Accession Version | NM_001026032.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1716bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Cell death protein 4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001026032.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGCTCTGCG AAATCGAATG CCGCGCTTTG AGCACGGCAC ACACGAGGCT CATCCACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001021203.1 |
CDS | 1..1716 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001026032.2 |
1 | ATGCTCTGCG AAATCGAATG CCGCGCTTTG AGCACGGCAC ACACGAGGCT CATCCACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |