Gene Symbol | xbp-1 |
Entrez Gene ID | 175541 |
Full Name | X-box Binding Protein homolog |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » xbp-1 cDNA ORF clone
Gene Symbol | xbp-1 |
Entrez Gene ID | 175541 |
Full Name | X-box Binding Protein homolog |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001083176.3 | NP_001076645.1 | BZIP domain-containing protein |
NM_001083176.2 | NP_001076645.1 | X-box Binding Protein homolog |
NM_001083177.4 | NP_001076646.1 | BZIP domain-containing protein |
NM_001083177.3 | NP_001076646.1 | X-box Binding Protein homolog |
NM_001306671.1 | NP_001293600.1 | X-box Binding Protein homolog |
NM_001306671.2 | NP_001293600.1 | BZIP domain-containing protein |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
vitamin-D3-induced lifespan extension requires the stress response pathway genes skn-1, ire-1, and xbp-1.
Title: Vitamin D Promotes Protein Homeostasis and Longevity via the Stress Response Pathway Genes skn-1, ire-1, and xbp-1.
In conclusion, we identified PEK-1 as a mediator of hormesis in the mev-1 mutant of C. elegans which is induced by simultaneous inhibition of XBP-1 and its splicing activator IRE-1 and mediated through activation of the proteasome.
Title: PEK-1 is crucial for hormesis induced by inhibition of the IRE-1/XBP-1 pathway in the Caenorhabditis elegans mev-1 mutant.
RTCB-1 (worm ortholog of human HSPC117) is required for the neuroprotective role, which, in turn, is mediated through XBP-1 in a model of neurodegenerative disease.
Title: RTCB-1 mediates neuroprotection via XBP-1 mRNA splicing in the unfolded protein response pathway.
Our results indicated that abolishing sumoylation enhanced calreticulin expression in an XBP-1-dependent manner, and the resulting increase in calreticulin counteracted ER stress.
Title: Sumoylation regulates ER stress response by modulating calreticulin gene expression in XBP-1-dependent mode in Caenorhabditis elegans.
Impairment of proteasome function elevates autophagy activity via XBP-1-mediated ER stress response.
Title: Genome-wide screen identifies signaling pathways that regulate autophagy during Caenorhabditis elegans development.
The following xbp-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the xbp-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa340389 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306671.1 , NM_001306671.2 | |
Accession Version | NM_001306671.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 951bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | X-box Binding Protein homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). COMPLETENESS: incomplete on both ends. |
1 | ATGAGCAACT ATCCAAAACG TATTTATGTG CTCCCAGCAC GCCACGTGGC AGCGCCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293600.1 |
CDS | 1..951 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306671.1 |
1 | ATGAGCAACT ATCCAAAACG TATTTATGTG CTCCCAGCAC GCCACGTGGC AGCGCCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340389 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306671.1 , NM_001306671.2 | |
Accession Version | NM_001306671.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 951bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | BZIP domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001306671.1. |
1 | ATGAGCAACT ATCCAAAACG TATTTATGTG CTCCCAGCAC GCCACGTGGC AGCGCCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293600.1 |
CDS | 163..1113 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306671.2 |
1 | ATGAGCAACT ATCCAAAACG TATTTATGTG CTCCCAGCAC GCCACGTGGC AGCGCCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341029 | |
Clone ID Related Accession (Same CDS sequence) | NM_001083176.3 , NM_001083176.2 | |
Accession Version | NM_001083176.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | BZIP domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001083176.2. |
1 | ATGAGCAACT ATCCAAAACG TATTTATGTG CTCCCAGCAC GCCACGTGGC AGCGCCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001076645.1 |
CDS | 175..1182 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001083176.3 |
1 | ATGAGCAACT ATCCAAAACG TATTTATGTG CTCCCAGCAC GCCACGTGGC AGCGCCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341029 | |
Clone ID Related Accession (Same CDS sequence) | NM_001083176.3 , NM_001083176.2 | |
Accession Version | NM_001083176.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1008bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | X-box Binding Protein homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_001083176.1. COMPLETENESS: incomplete on both ends. |
1 | ATGAGCAACT ATCCAAAACG TATTTATGTG CTCCCAGCAC GCCACGTGGC AGCGCCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001076645.1 |
CDS | 1..1008 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001083176.2 |
1 | ATGAGCAACT ATCCAAAACG TATTTATGTG CTCCCAGCAC GCCACGTGGC AGCGCCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341030 | |
Clone ID Related Accession (Same CDS sequence) | NM_001083177.4 , NM_001083177.3 | |
Accession Version | NM_001083177.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | BZIP domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001083177.3. |
1 | ATGAGCAACT ATCCAAAACG TATTTATGTG CTCCCAGCAC GCCACGTGGC AGCGCCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001076646.1 |
CDS | 175..1038 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001083177.4 |
1 | ATGAGCAACT ATCCAAAACG TATTTATGTG CTCCCAGCAC GCCACGTGGC AGCGCCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341030 | |
Clone ID Related Accession (Same CDS sequence) | NM_001083177.4 , NM_001083177.3 | |
Accession Version | NM_001083177.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | X-box Binding Protein homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_001083177.2. COMPLETENESS: incomplete on both ends. |
1 | ATGAGCAACT ATCCAAAACG TATTTATGTG CTCCCAGCAC GCCACGTGGC AGCGCCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001076646.1 |
CDS | 1..864 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001083177.3 |
1 | ATGAGCAACT ATCCAAAACG TATTTATGTG CTCCCAGCAC GCCACGTGGC AGCGCCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |