Gene Symbol | grk-2 |
Entrez Gene ID | 175223 |
Full Name | G protein-coupled receptor kinase 2 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » grk-2 cDNA ORF clone
Gene Symbol | grk-2 |
Entrez Gene ID | 175223 |
Full Name | G protein-coupled receptor kinase 2 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_064834.4 | NP_497235.2 | G protein-coupled receptor kinase 2 |
NM_064834.5 | NP_497235.2 | G protein-coupled receptor kinase 2 |
Homo sapiens (human) | ADRBK2 | NP_005151.2 |
Caenorhabditis elegans (roundworm) | grk-2 | NP_497235.2 |
Pan troglodytes (chimpanzee) | ADRBK2 | XP_003317197.1 |
Mus musculus (house mouse) | Adrbk2 | NP_796052.2 |
Canis lupus familiaris (dog) | ADRBK2 | XP_543453.3 |
Drosophila melanogaster (fruit fly) | Gprk1 | NP_001163051.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012026 | XP_320502.4 |
Xenopus tropicalis (tropical clawed frog) | adrbk2 | XP_002932117.2 |
ADRBK2 | XP_001104308.1 | |
Bos taurus (cattle) | ADRBK2 | NP_776925.1 |
Rattus norvegicus (Norway rat) | Adrbk2 | NP_037029.1 |
Gallus gallus (chicken) | ADRBK2 | XP_415195.4 |
Danio rerio (zebrafish) | adrbk2 | NP_001128197.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Genetic epistasis experiments suggest that GRK-2 acts on the D2-like dopamine receptor DOP-3 to inhibit Go signaling and positively modulate NCA-1 and NCA-2 activity.
Title: Dopamine negatively modulates the NCA ion channels in C. elegans.
These results demonstrate that GRK-2 modulates 5-HT metabolism by regulating AMX-2 function and that 5-HIAA may function in the SER-1 signaling pathway.
Title: G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in
We have demonstrated functional roles for broadly conserved GRK2/3 structural domains in the in vivo regulation of organismal behavior.
Title: Structural domains required for Caenorhabditis elegans G protein-coupled receptor kinase 2 (GRK-2) function in vivo.
The following grk-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the grk-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa341027 | |
Clone ID Related Accession (Same CDS sequence) | NM_064834.4 , NM_064834.5 | |
Accession Version | NM_064834.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2124bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | G protein-coupled receptor kinase 2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_064834.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGCAGACT TGGAAGCAGT GCTGGCTGAC GTCAGCTACC TGATGGCAAT GGAGAAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_497235.2 |
CDS | 1..2124 |
Translation |
Target ORF information:
Target ORF information:
|
NM_064834.4 |
1 | ATGGCAGACT TGGAAGCAGT GCTGGCTGAC GTCAGCTACC TGATGGCAAT GGAGAAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341027 | |
Clone ID Related Accession (Same CDS sequence) | NM_064834.4 , NM_064834.5 | |
Accession Version | NM_064834.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2124bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | G protein-coupled receptor kinase 2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_064834.4. |
1 | ATGGCAGACT TGGAAGCAGT GCTGGCTGAC GTCAGCTACC TGATGGCAAT GGAGAAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_497235.2 |
CDS | 8..2131 |
Translation |
Target ORF information:
Target ORF information:
|
NM_064834.5 |
1 | ATGGCAGACT TGGAAGCAGT GCTGGCTGAC GTCAGCTACC TGATGGCAAT GGAGAAGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |