Gene Symbol | lgg-1 |
Entrez Gene ID | 174050 |
Full Name | Protein lgg-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » lgg-1 cDNA ORF clone
Gene Symbol | lgg-1 |
Entrez Gene ID | 174050 |
Full Name | Protein lgg-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_062876.5 | NP_495277.1 | Protein lgg-1 |
NM_062876.6 | NP_495277.1 | Protein lgg-1 |
GABARAPL1 | XP_001115102.1 | |
Canis lupus familiaris (dog) | GABARAPL1 | XP_005637218.1 |
Caenorhabditis elegans (roundworm) | lgg-1 | NP_495277.1 |
Eremothecium gossypii | AGOS_AER396W | NP_985251.1 |
Homo sapiens (human) | GABARAPL1 | NP_113600.1 |
Drosophila melanogaster (fruit fly) | Atg8a | NP_727447.1 |
Kluyveromyces lactis | KLLA0E20593g | XP_454881.1 |
Bos taurus (cattle) | GABARAPL1 | NP_001028788.1 |
Mus musculus (house mouse) | Gabarapl1 | NP_065615.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002685 | XP_312238.3 |
Saccharomyces cerevisiae (baker's yeast) | ATG8 | NP_009475.1 |
Schizosaccharomyces pombe (fission yeast) | atg8 | NP_596531.1 |
Neurospora crassa | NCU01545 | XP_956248.1 |
Arabidopsis thaliana (thale cress) | ATG8D | NP_178631.1 |
Pan troglodytes (chimpanzee) | GABARAPL1 | XP_001146214.1 |
Rattus norvegicus (Norway rat) | Gabarapl1 | NP_001037759.1 |
Gallus gallus (chicken) | GABARAPL1 | XP_001231888.1 |
Danio rerio (zebrafish) | LOC793200 | XP_003199067.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_01062 | XP_003717877.1 |
Xenopus tropicalis (tropical clawed frog) | gabarapl1 | NP_001025652.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data show the N-terminal of LGG-1 and LGG-2 adopts the closed and open form, respectively. They have distinct binding pockets that prefer different residues, influencing binding specificity and differential interaction with autophagy proteins.
Title: Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy.
During allophagy LGG-1 acts upstream of LGG-2 to allow its localization to autophagosomes.
Title: The C. elegans LC3 acts downstream of GABARAP to degrade autophagosomes by interacting with the HOPS subunit VPS39.
both LGG-2 and LGG-1 act synergistically and are involved in dauer formation and longevity of the worm.
Title: The autophagosomal protein LGG-2 acts synergistically with LGG-1 in dauer formation and longevity in C. elegans.
Inactivation of unc-51, bec-1 and lgg-1, the worm counterparts of the yeast autophagy genes Atg1, Atg6 and Atg8 respectively, partially suppresses degeneration of neurons with toxic ion channel variants.
Title: Influence of autophagy genes on ion-channel-dependent neuronal degeneration in Caenorhabditis elegans.
The following lgg-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lgg-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa338811 | |
Clone ID Related Accession (Same CDS sequence) | NM_062876.5 , NM_062876.6 | |
Accession Version | NM_062876.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Protein lgg-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_062876.4. COMPLETENESS: incomplete on both ends. |
1 | ATGAAGTGGG CTTACAAGGA GGAGAACAAC TTTGAGAAGC GTCGTGCCGA AGGAGACAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_495277.1 |
CDS | 1..372 |
Translation |
Target ORF information:
Target ORF information:
|
NM_062876.5 |
1 | ATGAAGTGGG CTTACAAGGA GGAGAACAAC TTTGAGAAGC GTCGTGCCGA AGGAGACAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa338811 | |
Clone ID Related Accession (Same CDS sequence) | NM_062876.5 , NM_062876.6 | |
Accession Version | NM_062876.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Protein lgg-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_062876.5. |
1 | ATGAAGTGGG CTTACAAGGA GGAGAACAAC TTTGAGAAGC GTCGTGCCGA AGGAGACAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_495277.1 |
CDS | 34..405 |
Translation |
Target ORF information:
Target ORF information:
|
NM_062876.6 |
1 | ATGAAGTGGG CTTACAAGGA GGAGAACAAC TTTGAGAAGC GTCGTGCCGA AGGAGACAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |