Gene Symbol | sys-1 |
Entrez Gene ID | 172859 |
Full Name | SYmmetrical Sister cell hermaphrodite gonad defect |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » sys-1 cDNA ORF clone
Gene Symbol | sys-1 |
Entrez Gene ID | 172859 |
Full Name | SYmmetrical Sister cell hermaphrodite gonad defect |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_060239.4 | NP_492640.1 | SYmmetrical Sister cell hermaphrodite gonad defect |
NM_001313509.1 | NP_001300438.1 | SYmmetrical Sister cell hermaphrodite gonad defect |
NM_060238.3 | NP_492639.1 | SYmmetrical Sister cell hermaphrodite gonad defect |
NM_060238.4 | NP_492639.1 | SYmmetrical Sister cell hermaphrodite gonad defect |
NM_060239.5 | NP_492640.1 | SYmmetrical Sister cell hermaphrodite gonad defect |
NM_001313509.2 | NP_001300438.1 | SYmmetrical Sister cell hermaphrodite gonad defect |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
these results indicate that SYS-1 and POP-1 levels are influenced by the parent cell's SYS-1/POP-1 levels and this may provide an additional mechanism by which POP-1 regulates distinct targets in different developmental contexts.
Title: Quantitative Differences in Nuclear ?-catenin and TCF Pattern Embryonic Cells in C. elegans.
Data show that centrosomal targeting of SYS-1 promotes its degradation during asymmetric cell division.
Title: Centrosome-Associated Degradation Limits ?-Catenin Inheritance by Daughter Cells after Asymmetric Division.
SYS-1 and POP-1 nuclear levels are regulated in opposite directions; the C terminus of POP-1 is essential for LIT-1 phosphorylation and is specifically bound by the diverged beta-catenin WRM-1
Title: Distinct and mutually inhibitory binding by two divergent ?-catenins coordinates TCF levels and activity in C. elegans.
Animals with reduced function of the beta-catenins SYS-1 and WRM-1 have as few as 3 seam cells. The 'Wnt/beta-catenin asymmetry' pathway is required for the proper stem cell-like asymmetric division of seam cells.
Title: Wnt signaling controls the stem cell-like asymmetric division of the epithelial seam cells during C. elegans larval development.
Either the DIX or DEP domain of DSH-2 is capable of activating the Wnt/beta-catenin asymmetry pathway and regulating anterior-posterior fate decisions required for proper morphogenesis.
Title: The N- or C-terminal domains of DSH-2 can activate the C. elegans Wnt/beta-catenin asymmetry pathway.
The following sys-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sys-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa336201 | |
Clone ID Related Accession (Same CDS sequence) | NM_060239.4 , NM_060239.5 | |
Accession Version | NM_060239.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | SYmmetrical Sister cell hermaphrodite gonad defect | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_060239.3. COMPLETENESS: incomplete on both ends. |
1 | ATGCATTCAA CCGGAGAGCC TCAACGAGGG CCCGCCGGCC CATATCATCA TCCGATGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492640.1 |
CDS | 1..720 |
Translation |
Target ORF information:
Target ORF information:
|
NM_060239.4 |
1 | ATGCATTCAA CCGGAGAGCC TCAACGAGGG CCCGCCGGCC CATATCATCA TCCGATGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336201 | |
Clone ID Related Accession (Same CDS sequence) | NM_060239.4 , NM_060239.5 | |
Accession Version | NM_060239.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | SYmmetrical Sister cell hermaphrodite gonad defect | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_060239.4. |
1 | ATGCATTCAA CCGGAGAGCC TCAACGAGGG CCCGCCGGCC CATATCATCA TCCGATGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492640.1 |
CDS | 40..759 |
Translation |
Target ORF information:
Target ORF information:
|
NM_060239.5 |
1 | ATGCATTCAA CCGGAGAGCC TCAACGAGGG CCCGCCGGCC CATATCATCA TCCGATGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa335738 | |
Clone ID Related Accession (Same CDS sequence) | NM_060238.3 , NM_060238.4 | |
Accession Version | NM_060238.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | SYmmetrical Sister cell hermaphrodite gonad defect | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_060238.2. COMPLETENESS: incomplete on both ends. |
1 | ATGCATTCAA CCGGAGAGCC TCAACGAGGG CCCGCCGGCC CATATCATCA TCCGATGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492639.1 |
CDS | 1..2436 |
Translation |
Target ORF information:
Target ORF information:
|
NM_060238.3 |
1 | ATGCATTCAA CCGGAGAGCC TCAACGAGGG CCCGCCGGCC CATATCATCA TCCGATGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa335738 | |
Clone ID Related Accession (Same CDS sequence) | NM_060238.3 , NM_060238.4 | |
Accession Version | NM_060238.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | SYmmetrical Sister cell hermaphrodite gonad defect | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_060238.3. |
1 | ATGCATTCAA CCGGAGAGCC TCAACGAGGG CCCGCCGGCC CATATCATCA TCCGATGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492639.1 |
CDS | 40..2475 |
Translation |
Target ORF information:
Target ORF information:
|
NM_060238.4 |
1 | ATGCATTCAA CCGGAGAGCC TCAACGAGGG CCCGCCGGCC CATATCATCA TCCGATGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa337284 | |
Clone ID Related Accession (Same CDS sequence) | NM_001313509.1 , NM_001313509.2 | |
Accession Version | NM_001313509.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | SYmmetrical Sister cell hermaphrodite gonad defect | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). COMPLETENESS: incomplete on both ends. |
1 | ATGTCATATC ATCAAGGAGA CGATCGAATG TCAATGCTCA GTGTGAATAC AACCATGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001300438.1 |
CDS | 1..2037 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001313509.1 |
1 | ATGTCATATC ATCAAGGAGA CGATCGAATG TCAATGCTCA GTGTGAATAC AACCATGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa337284 | |
Clone ID Related Accession (Same CDS sequence) | NM_001313509.1 , NM_001313509.2 | |
Accession Version | NM_001313509.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2037bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | SYmmetrical Sister cell hermaphrodite gonad defect | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001313509.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGTCATATC ATCAAGGAGA CGATCGAATG TCAATGCTCA GTGTGAATAC AACCATGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001300438.1 |
CDS | 1..2037 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001313509.2 |
1 | ATGTCATATC ATCAAGGAGA CGATCGAATG TCAATGCTCA GTGTGAATAC AACCATGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |