Gene Symbol | nhr-49 |
Entrez Gene ID | 172839 |
Full Name | Nuclear Hormone Receptor family |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » nhr-49 cDNA ORF clone
Gene Symbol | nhr-49 |
Entrez Gene ID | 172839 |
Full Name | Nuclear Hormone Receptor family |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_060211.5 | NP_492612.1 | Nuclear hormone receptor family member nhr-49 |
NM_181998.4 | NP_871798.1 | Nuclear hormone receptor family member nhr-49 |
NM_060212.4 | NP_492613.1 | Nuclear hormone receptor family member nhr-49 |
NM_001264305.1 | NP_001251234.1 | Nuclear hormone receptor family member nhr-49 |
NM_001264305.2 | NP_001251234.1 | NR LBD domain-containing protein |
NM_060211.4 | NP_492612.1 | Nuclear hormone receptor family member nhr-49 |
NM_181998.5 | NP_871798.1 | Nuclear hormone receptor family member nhr-49 |
NM_181999.5 | NP_871799.1 | Nuclear hormone receptor family member nhr-49 |
NM_060212.5 | NP_492613.1 | Nuclear hormone receptor family member nhr-49 |
NM_181999.4 | NP_871799.1 | Nuclear hormone receptor family member nhr-49 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Reduced signaling through the insulin-like receptor daf-2/InsR in the maternal soma causes constitutively large progeny, and its effector daf-16/FoxO is required for this effect. nhr-49/Hnf4, pha-4/FoxA, and skn-1/Nrf also regulate progeny-size plasticity. Genetic analysis suggests that insulin-like signaling controls progeny size in part through regulation of nhr-49/Hnf4, and that pha-4/FoxA and skn-1/Nrf function
Title: Maternal Diet and Insulin-Like Signaling Control Intergenerational Plasticity of Progeny Size and Starvation Resistance.
AAK-2 regulates oxidative metabolism in Caenorhabditis elegans through the NHR-49 and MDT-15 transcriptional regulators.
Title: AMP-Activated Protein Kinase Regulates Oxidative Metabolism in Caenorhabditis elegans through the NHR-49 and MDT-15 Transcriptional Regulators.
NHR-49 may facilitate the adaptation to loss of reproductive potential through synchronized enhancement of fatty-acid oxidation and desaturation,and orchestrating a lipid profile conducive for somatic maintenance and longevity.
Title: Germline signals deploy NHR-49 to modulate fatty-acid ?-oxidation and desaturation in somatic tissues of C. elegans.
Data (including data from studies in mutant and transgenic strains) suggest that stress response to fasting (lysosomal lipid accumulation) is co-ordinately regulated by EGL-4/PKG (protein kinase G) and nuclear hormone receptor NHR-49.
Title: PKG and NHR-49 signalling co-ordinately regulate short-term fasting-induced lysosomal lipid accumulation in C. elegans.
Fibrates promote C. elegans longevity in an NHR-49-dependent manner possibly by promoting mitohormesis and suggesting that these compounds may promote lifespan also in mammals.
Title: Lipid-lowering fibrates extend C. elegans lifespan in a NHR-49/PPARalpha-dependent manner.
The following nhr-49 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the nhr-49 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa335844 | |
Clone ID Related Accession (Same CDS sequence) | NM_060211.5 , NM_060211.4 | |
Accession Version | NM_060211.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1434bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-49 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_060211.4. |
1 | ATGGACCTAG TAGATCCTCT TGCGGAACCA TGTGCCGTTT GTGGTGACAA ATCAACTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492612.1 |
CDS | 3..1436 |
Translation |
Target ORF information:
Target ORF information:
|
NM_060211.5 |
1 | ATGGACCTAG TAGATCCTCT TGCGGAACCA TGTGCCGTTT GTGGTGACAA ATCAACTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa335844 | |
Clone ID Related Accession (Same CDS sequence) | NM_060211.5 , NM_060211.4 | |
Accession Version | NM_060211.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1434bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-49 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_060211.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGACCTAG TAGATCCTCT TGCGGAACCA TGTGCCGTTT GTGGTGACAA ATCAACTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492612.1 |
CDS | 1..1434 |
Translation |
Target ORF information:
Target ORF information:
|
NM_060211.4 |
1 | ATGGACCTAG TAGATCCTCT TGCGGAACCA TGTGCCGTTT GTGGTGACAA ATCAACTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336019 | |
Clone ID Related Accession (Same CDS sequence) | NM_060212.4 , NM_060212.5 | |
Accession Version | NM_060212.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-49 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_060212.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGACCTAG TAGATCCTCT TGCGGAACCA TGTGCCGTTT GTGGTGACAA ATCAACTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492613.1 |
CDS | 1..1431 |
Translation |
Target ORF information:
Target ORF information:
|
NM_060212.4 |
1 | ATGGACCTAG TAGATCCTCT TGCGGAACCA TGTGCCGTTT GTGGTGACAA ATCAACTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336019 | |
Clone ID Related Accession (Same CDS sequence) | NM_060212.4 , NM_060212.5 | |
Accession Version | NM_060212.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-49 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_060212.4. |
1 | ATGGACCTAG TAGATCCTCT TGCGGAACCA TGTGCCGTTT GTGGTGACAA ATCAACTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492613.1 |
CDS | 3..1433 |
Translation |
Target ORF information:
Target ORF information:
|
NM_060212.5 |
1 | ATGGACCTAG TAGATCCTCT TGCGGAACCA TGTGCCGTTT GTGGTGACAA ATCAACTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336080 | |
Clone ID Related Accession (Same CDS sequence) | NM_001264305.1 , NM_001264305.2 | |
Accession Version | NM_001264305.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1065bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-49 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). COMPLETENESS: incomplete on both ends. |
1 | ATGGGACAAG AGAATATGCG AACAGTTCCA CAATCCAGCA GTGTCATTGA TGCTTTAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001251234.1 |
CDS | 1..1065 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001264305.1 |
1 | ATGGGACAAG AGAATATGCG AACAGTTCCA CAATCCAGCA GTGTCATTGA TGCTTTAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336080 | |
Clone ID Related Accession (Same CDS sequence) | NM_001264305.1 , NM_001264305.2 | |
Accession Version | NM_001264305.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1065bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | NR LBD domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001264305.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGGGACAAG AGAATATGCG AACAGTTCCA CAATCCAGCA GTGTCATTGA TGCTTTAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001251234.1 |
CDS | 1..1065 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001264305.2 |
1 | ATGGGACAAG AGAATATGCG AACAGTTCCA CAATCCAGCA GTGTCATTGA TGCTTTAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336285 | |
Clone ID Related Accession (Same CDS sequence) | NM_181999.5 , NM_181999.4 | |
Accession Version | NM_181999.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1461bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-49 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_181999.4. |
1 | ATGAAGAATC TTCAGATGAT TGTAATCATG GACCTAGTAG ATCCTCTTGC GGAACCATGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_871799.1 |
CDS | 66..1526 |
Translation |
Target ORF information:
Target ORF information:
|
NM_181999.5 |
1 | ATGAAGAATC TTCAGATGAT TGTAATCATG GACCTAGTAG ATCCTCTTGC GGAACCATGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336285 | |
Clone ID Related Accession (Same CDS sequence) | NM_181999.5 , NM_181999.4 | |
Accession Version | NM_181999.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1461bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-49 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_181999.3. COMPLETENESS: incomplete on both ends. |
1 | ATGAAGAATC TTCAGATGAT TGTAATCATG GACCTAGTAG ATCCTCTTGC GGAACCATGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_871799.1 |
CDS | 1..1461 |
Translation |
Target ORF information:
Target ORF information:
|
NM_181999.4 |
1 | ATGAAGAATC TTCAGATGAT TGTAATCATG GACCTAGTAG ATCCTCTTGC GGAACCATGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336284 | |
Clone ID Related Accession (Same CDS sequence) | NM_181998.4 , NM_181998.5 | |
Accession Version | NM_181998.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1506bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-49 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_181998.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGACTACT TTCTTGATGC TTCTAAACAT ATTCAGTTGA ATCAAATTGA TGAAGAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_871798.1 |
CDS | 1..1506 |
Translation |
Target ORF information:
Target ORF information:
|
NM_181998.4 |
1 | ATGGACTACT TTCTTGATGC TTCTAAACAT ATTCAGTTGA ATCAAATTGA TGAAGAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336284 | |
Clone ID Related Accession (Same CDS sequence) | NM_181998.4 , NM_181998.5 | |
Accession Version | NM_181998.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1506bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-49 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_181998.4. |
1 | ATGGACTACT TTCTTGATGC TTCTAAACAT ATTCAGTTGA ATCAAATTGA TGAAGAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_871798.1 |
CDS | 56..1561 |
Translation |
Target ORF information:
Target ORF information:
|
NM_181998.5 |
1 | ATGGACTACT TTCTTGATGC TTCTAAACAT ATTCAGTTGA ATCAAATTGA TGAAGAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |