Gene Symbol | FFAR2 |
Entrez Gene ID | 522431 |
Full Name | free fatty acid receptor 2 |
Synonyms | GPR43 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » FFAR2 cDNA ORF clone
Gene Symbol | FFAR2 |
Entrez Gene ID | 522431 |
Full Name | free fatty acid receptor 2 |
Synonyms | GPR43 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_005218963.4 | XP_005219020.1 | free fatty acid receptor 2 isoform X1 |
NM_001163784.1 | NP_001157256.1 | free fatty acid receptor 2 |
XM_005218963.3 | XP_005219020.1 | free fatty acid receptor 2 isoform X1 |
Canis lupus familiaris (dog) | FFAR2 | XP_005616767.1 |
Mus musculus (house mouse) | Ffar2 | NP_001161981.1 |
Rattus norvegicus (Norway rat) | Ffar2 | NP_001005877.1 |
Gallus gallus (chicken) | LOC429354 | XP_426910.4 |
Gallus gallus (chicken) | LOC100858431 | XP_004950711.1 |
Gallus gallus (chicken) | LOC101749263 | XP_004950270.1 |
Gallus gallus (chicken) | LOC429347 | XP_004950704.1 |
Gallus gallus (chicken) | LOC100859086 | XP_003643854.2 |
Danio rerio (zebrafish) | LOC100004095 | XP_001920566.1 |
Pan troglodytes (chimpanzee) | FFAR2 | XP_512587.2 |
FFAR2 | XP_001095000.1 | |
Gallus gallus (chicken) | LOC101747502 | XP_004950186.1 |
Gallus gallus (chicken) | LOC777322 | XP_004951012.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100486488 | XP_002938241.1 |
Bos taurus (cattle) | FFAR2 | NP_001157256.1 |
Gallus gallus (chicken) | LOC430168 | XP_004950966.1 |
Gallus gallus (chicken) | LOC100858117 | XP_003643742.2 |
Gallus gallus (chicken) | LOC101747469 | XP_004950708.1 |
Gallus gallus (chicken) | LOC101749787 | XP_004950719.1 |
Danio rerio (zebrafish) | LOC100004033 | XP_001343441.3 |
Danio rerio (zebrafish) | si:dkey-211g8.6 | NP_001076364.1 |
Danio rerio (zebrafish) | LOC571502 | XP_700191.4 |
Gallus gallus (chicken) | LOC776487 | XP_001236005.2 |
Gallus gallus (chicken) | LOC100857826 | XP_004950188.1 |
Gallus gallus (chicken) | LOC430071 | XP_427629.3 |
Gallus gallus (chicken) | LOC429574 | XP_004950637.1 |
Gallus gallus (chicken) | LOC100858697 | XP_003644001.1 |
Homo sapiens (human) | FFAR2 | NP_005297.1 |
Gallus gallus (chicken) | LOC777462 | XP_001236909.2 |
Gallus gallus (chicken) | LOC430746 | XP_004951134.1 |
Gallus gallus (chicken) | LOC101752209 | XP_004950707.1 |
Gallus gallus (chicken) | LOC101747578 | XP_004950709.1 |
Gallus gallus (chicken) | LOC100859369 | XP_004950727.1 |
Gallus gallus (chicken) | LOC100859180 | XP_004950219.1 |
Gallus gallus (chicken) | LOC429280 | XP_004950908.1 |
Gallus gallus (chicken) | LOC100857419 | XP_003643822.2 |
Expression of metabolic sensing receptors in adipose tissues of periparturient dairy cows with differing extent of negative energy balance.
Friedrichs P, Sauerwein H, Huber K, Locher LF, Rehage J, Meyer U, D?nicke S, Kuhla B, Mielenz M
Animal : an international journal of animal bioscience10(4)623-32(2016 Apr)
Co-culture of bovine muscle satellite cells with preadipocytes increases PPAR? and C/EBP? gene expression in differentiated myoblasts and increases GPR43 gene expression in adipocytes.
Choi SH, Chung KY, Johnson BJ, Go GW, Kim KH, Choi CW, Smith SB
The Journal of nutritional biochemistry24(3)539-43(2013 Mar)
Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs.
Hudson BD, Christiansen E, Tikhonova IG, Grundmann M, Kostenis E, Adams DR, Ulven T, Milligan G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology26(12)4951-65(2012 Dec)
Identification and characterization of the bovine G protein-coupled receptor GPR41 and GPR43 genes.
Wang A, Gu Z, Heid B, Akers RM, Jiang H
Journal of dairy science92(6)2696-705(2009 Jun)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
An inverse regulation of FFAR2 and FFAR3 expression over time and both receptors also showed an inverse mRNA abundance as induced by different portions of concentrate. Thus, indicating divergent nutrient sensing of both receptors in adipose tissues (AT) during the transition period.
Title: Expression of metabolic sensing receptors in adipose tissues of periparturient dairy cows with differing extent of negative energy balance.
Co-culture of adipocytes and myoblasts elicited an increase in C/EBPbeta and PPAR-gamma gene expression in differentiated myoblasts and an increase in GPR43 gene expression in adipocytes.
Title: Co-culture of bovine muscle satellite cells with preadipocytes increases PPAR? and C/EBP? gene expression in differentiated myoblasts and increases GPR43 gene expression in adipocytes.
Data indicate that a single mutation in human FFA2 of C4.57G resulted in a human FFA2 receptor with ligand selectivity similar to the bovine receptor.
Title: Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs.
GPR43 gene contains 2 exons and transcription of this gene is initiated from a single start site
Title: Identification and characterization of the bovine G protein-coupled receptor GPR41 and GPR43 genes.
The following FFAR2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FFAR2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa02382 | |
Clone ID Related Accession (Same CDS sequence) | XM_005218963.4 , NM_001163784.1 , XM_005218963.3 | |
Accession Version | NM_001163784.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-13 | |
Organism | Bos taurus(cattle) | |
Product | free fatty acid receptor 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from FJ562212.1. On Aug 8, 2009 this sequence version replaced XM_600712.4. ##Evidence-Data-START## Transcript exon combination :: FJ562212.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145415, SAMN03145447 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCAGACT GGGATAGCTC CTTGATCCTC ACGGCTTACA TTATTATCTT GCTCACCGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001157256.1 |
CDS | 132..1121 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCCAGACT GGGATAGCTC CTTGATCCTC ACGGCTTACA TTATTATCTT GCTCACCGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa02382 | |
Clone ID Related Accession (Same CDS sequence) | XM_005218963.4 , NM_001163784.1 , XM_005218963.3 | |
Accession Version | XM_005218963.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | free fatty acid receptor 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037345.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005218963.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCAGACT GGGATAGCTC CTTGATCCTC ACGGCTTACA TTATTATCTT GCTCACCGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005219020.1 |
CDS | 638..1627 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCCAGACT GGGATAGCTC CTTGATCCTC ACGGCTTACA TTATTATCTT GCTCACCGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa02382 | |
Clone ID Related Accession (Same CDS sequence) | XM_005218963.4 , NM_001163784.1 , XM_005218963.3 | |
Accession Version | XM_005218963.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | free fatty acid receptor 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104465.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005218963.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCAGACT GGGATAGCTC CTTGATCCTC ACGGCTTACA TTATTATCTT GCTCACCGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005219020.1 |
CDS | 631..1620 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCAGACT GGGATAGCTC CTTGATCCTC ACGGCTTACA TTATTATCTT GCTCACCGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Expression of metabolic sensing receptors in adipose tissues of periparturient dairy cows with differing extent of negative energy balance. |
Co-culture of bovine muscle satellite cells with preadipocytes increases PPAR? and C/EBP? gene expression in differentiated myoblasts and increases GPR43 gene expression in adipocytes. |
Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs. |
Identification and characterization of the bovine G protein-coupled receptor GPR41 and GPR43 genes. |
A whole-genome assembly of the domestic cow, Bos taurus. |