Gene Symbol | PFN1 |
Entrez Gene ID | 513895 |
Full Name | profilin 1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » PFN1 cDNA ORF clone
Gene Symbol | PFN1 |
Entrez Gene ID | 513895 |
Full Name | profilin 1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_001015592.1 | NP_001015592.1 | profilin-1 |
Profilin oligomerization and its effect on poly (L-proline) binding and phosphorylation.
Korupolu RV, Achary MS, Aneesa F, Sathish K, Wasia R, Sairam M, Nagarajaram HA, Singh SS
International journal of biological macromolecules45(3)265-73(2009 Oct)
Profilin and actin-related proteins regulate microfilament dynamics during early mammalian embryogenesis.
Rawe VY, Payne C, Schatten G
Human reproduction (Oxford, England)21(5)1143-53(2006 May)
The open nucleotide pocket of the profilin/actin x-ray structure is unstable and closes in the absence of profilin.
Minehardt TJ, Kollman PA, Cooke R, Pate E
Biophysical journal90(7)2445-9(2006 Apr)
Nitration of profilin effects its interaction with poly (L-proline) and actin.
Kasina S, Rizwani W, Radhika KV, Singh SS
Journal of biochemistry138(6)687-95(2005 Dec)
Characterization of 954 bovine full-CDS cDNA sequences.
Harhay GP, Sonstegard TS, Keele JW, Heaton MP, Clawson ML, Snelling WM, Wiedmann RT, Van Tassell CP, Smith TP
BMC genomics6166(2005 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Phosphorylation studies indicate that profilin dimers are not phosphorylated while teramers are preferentially phosphorylated over monomers.
Title: Profilin oligomerization and its effect on poly (L-proline) binding and phosphorylation.
Profilin regulates actin dynamics both within the cytoplasm and inside the nuclei of developing mammalian embryos.
Title: Profilin and actin-related proteins regulate microfilament dynamics during early mammalian embryogenesis.
biophysical analysis reveals that the open nucleotide pocket of the profilin/actin x-ray structure is unstable and closes in the absence of profilin
Title: The open nucleotide pocket of the profilin/actin x-ray structure is unstable and closes in the absence of profilin.
nitric oxide and free radicals produced under different conditions could alter the functions of profilin through nitration, such as its interaction with actin and poly (l-proline).
Title: Nitration of profilin effects its interaction with poly (L-proline) and actin.
The following PFN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PFN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa43301 | |
Clone ID Related Accession (Same CDS sequence) | NM_001015592.1 | |
Accession Version | NM_001015592.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Bos taurus(cattle) | |
Product | profilin-1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BT021078.1. On Apr 21, 2005 this sequence version replaced XM_591656.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BT021078.1, BC102240.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCGGGT GGAACGCCTA CATCGACAAC CTCATGGCGG ACGGGACCTG TCAGGACGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001015592.1 |
CDS | 143..565 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001015592.1 |
1 | ATGGCCGGGT GGAACGCCTA CATCGACAAC CTCATGGCGG ACGGGACCTG TCAGGACGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Profilin oligomerization and its effect on poly (L-proline) binding and phosphorylation. |
Profilin and actin-related proteins regulate microfilament dynamics during early mammalian embryogenesis. |
The open nucleotide pocket of the profilin/actin x-ray structure is unstable and closes in the absence of profilin. |
Nitration of profilin effects its interaction with poly (L-proline) and actin. |
Characterization of 954 bovine full-CDS cDNA sequences. |