RELA cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	RELA
Entrez Gene ID	508233
Full Name	RELA proto-oncogene, NF-kB subunit
General protein information	Preferred Names RELA proto-oncogene, NF-kB subunit Names transcription factor p65 NF-kappaB transcription factor p65 subunit v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001080242.2	NP_001073711.1	transcription factor p65

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Rela	NP_033071.1
Homo sapiens (human)	RELA	NP_068810.3
Canis lupus familiaris (dog)	RELA	XP_540850.2
Bos taurus (cattle)	RELA	NP_001073711.1
	RELA	XP_001113258.2
Gallus gallus (chicken)	RELA	NP_990460.1
Pan troglodytes (chimpanzee)	RELA	NP_001233559.1
Rattus norvegicus (Norway rat)	Rela	NP_954888.1
Xenopus tropicalis (tropical clawed frog)	rela	NP_001001211.1
Danio rerio (zebrafish)	rela	NP_001001839.2

Gene Ontology
Bibliography

Related articles in PubMed

High levels of acetoacetate and glucose increase expression of cytokines in bovine hepatocytes, through activation of the NF-?B signalling pathway.
Li Y, Ding H, Wang X, Liu L, Huang D, Zhang R, Guo L, Wang Z, Li X, Liu G, Wu J, Li X
The Journal of dairy research83(1)51-7(2016 Feb)

Cytopathic BVDV-1 strain induces immune marker production in bovine cells through the NF-?B signaling pathway.
Fredericksen F, Carrasco G, Villalba M, Olavarr?a VH
Molecular immunology68(2 Pt A)213-22(2015 Dec)

SREBP-1c overactivates ROS-mediated hepatic NF-?B inflammatory pathway in dairy cows with fatty liver.
Li X, Huang W, Gu J, Du X, Lei L, Yuan X, Sun G, Wang Z, Li X, Liu G
Cellular signalling27(10)2099-109(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Cytopathic bovine viral diarrhea virus strain induces immune marker production in bovine cells through the NF-kappaB signaling pathway.
Title: Cytopathic BVDV-1 strain induces immune marker production in bovine cells through the NF-?B signaling pathway.

Hepatic SREBP-1c-mediated lipid synthesis and the NF-kappaB inflammatory pathway were both overinduced in cows with fatty liver.
Title: SREBP-1c overactivates ROS-mediated hepatic NF-?B inflammatory pathway in dairy cows with fatty liver.

The role of NF-kappaB and C/EBP factors in regulating basal and pathogen-induced expression of both genes from cattle, is investigated.
Title: Lingual antimicrobial peptide and IL-8 expression are oppositely regulated by the antagonistic effects of NF-?B p65 and C/EBP? in mammary epithelial cells.

These results confirm that VEGI utilizes NF-kappaB as a pro-survival role factor in endothelial cells.
Title: Sensitization of endothelial cells to VEGI-induced apoptosis by inhibiting the NF-kappaB pathway.

the pathogen causing subclinical mastitis impairs NF-kappaB activation in MEC thereby severely weakening the immune response,induction of IL-8 and TNFalpha, in the udder
Title: Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 (CXCL8) expression in the udder.

The following RELA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RELA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa40299	NM_001080242.2 Latest version!	Bos taurus RELA proto-oncogene, NF-kB subunit (RELA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RELA ( NM_001080242.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001073711.1 Bos taurus RELA proto-oncogene, NF-kB subunit (RELA), mRNA.

Price & Availability↑

CloneID	OBa40299
Clone ID Related Accession (Same CDS sequence)	NM_001080242.2
Accession Version	NM_001080242.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-02
Organism	Bos taurus(cattle)
Product	transcription factor p65
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC133594.1. On Mar 8, 2007 this sequence version replaced NM_001080242.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC133594.1, DQ355511.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145412, SAMN03145413 [ECO:0000350] ##Evidence-Data-END##

ATGGACGACC TCTTCCCCCT CATCTTCCCT GCAGAGCCGG CGCAGGCCTC TGGCCCCTAT 
GTGGAGATCA TCGAGCAGCC CAAGCAGCGG GGCATGCGCT TCCGCTACAA GTGTGAGGGC 
CGCTCAGCTG GCAGCATCCC TGGAGAGAGG AGCACGGACA CCACCAAGAC CCACCCCACT 
ATCAAGATCA ATGGCTACAC CGGGCCAGGG ACAGTCCGCA TCTCCCTGGT CACCAAGGAC 
CCCCCTCACC GGCCTCACCC TCACGAGCTA GTGGGGAAAG ACTGCCGGGA TGGCTTCTAT 
GAGGCTGAGC TCTGCCCGGA CCGCTGCATC CACAGCTTTC AGAACCTGGG GATCCAGTGT 
GTAAAGAAGC GGGACCTGGA GCAGGCCATC AGCCAGCGCA TCCAGACCAA CAACAACCCC 
TTCCAAGTTC CCATAGAAGA GCAGCGCGGG GACTACGACC TGAATGCCGT CCGGCTCTGC 
TTCCAGGTGA CAGTGCGGGA CCCGGCAGGC AGGCCCCTCC GCCTGGCGCC TGTCCTCTCT 
CACCCCATCT TTGACAACCG CGCCCCCAAC ACCGCCGAGC TCAAGATCTG CCGGGTGAAT 
CGGAACTCTG GGAGCTGCCT CGGCGGGGAT GAGATCTTCC TGCTGTGTGA CAAGGTGCAG 
AAAGAGGACA TCGAGGTGTA TTTCACGGGA CCAGGCTGGG AGGCCCGAGG CTCTTTTTCA 
CAAGCTGACG TGCACCGGCA AGTGGCCATC GTGTTCCGGA CGCCGCCCTA CGCGGACCCC 
GGCCTGCAGG CCCCTGTGCG CGTCTCCATG CAGCTGCGGC GGCCTTCCGA TCGGGAGCTC 
AGTGAGCCCA TGGAATTCCA GTACTTGCCA GACACAGACG ATCGTCACCG GATTGAGGAG 
AAGCGCAAAA GGACGTACGA GACCTTCAAG AGCATCATGA AAAAGAGCCC TTTCAATGGA 
CCCACCGACC CCCGGCCTCC AACCCGGCGC ATCGCTGTGC CTAACCGCGG CTCAGCCTCC 
ATCCCCAAGC CAGCTCCCCA GCCCTATTCC TTTACGCCAT CTCTCAGCAC CATCAACTTT 
GAGGAGTTTT CCCCCATGGT CTTTCCTTCT GGGCAGATCC CAAGCCAGAC CTCGGCCTTG 
GCACCAGCCC CCACCCCGGT CCTGACCCAG ACCCAAGTCC TGGCCCCAGC CCCGGCCCCA 
GCCCCAGGCA TGGCATCAAC CCTGGCCCAG GCCCTAGCCC CAGGCCTGGC TCAGGCTGTG 
ACCCCGCCTG CCCCCAGGAC CAACCAGACC GGGGAAGGGA CACTGACAGA GGCCCTGCTG 
CAGCTGCAGT TTGATACCGA TGAAGACCTG GGGGCTCTGC TTGGCAACAA CACTGACCCT 
GCCGTGTTCA CAGACCTGGC ATCTGTCGAC AACTCTGAGT TTCAGCAGTT GCTGAACCAG 
GGTGTACCCA TGGGCCCCCA CACAGCTGAG CCCATGCTGA TGGAGTACCC TGAGGCTATA 
ACTCGCCTGG TGACAGGGTC CCAAAGGCCC CCTGACCCAG CTCCCACTCC CCTGGGGCCC 
CCTGGGCTCA CCAATGGCCT CCTCTCGGGG GATGAAGACT TCTCCTCCAT CGCGGATGTG 
GACTTCTCAG CCCTTCTGAG TCAGATCAGC TCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073711.1
CDS	85..1740
Translation	MDDLFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPAGRPLRLAPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPGLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFNGPTDPRPPTRRIAVPNRGSASIPKPAPQPYSFTPSLSTINFEEFSPMVFPSGQIPSQTSALAPAPTPVLTQTQVLAPAPAPAPGMASTLAQALAPGLAQAVTPPAPRTNQTGEGTLTEALLQLQFDTDEDLGALLGNNTDPAVFTDLASVDNSEFQQLLNQGVPMGPHTAEPMLMEYPEAITRLVTGSQRPPDPAPTPLGPPGLTNGLLSGDEDFSSIADVDFSALLSQISS

Target ORF information:

RefSeq Version	NM_001080242.2
Organism	Bos taurus(cattle)
Definition	Bos taurus RELA proto-oncogene, NF-kB subunit (RELA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080242.2

ORF Insert Sequence:

ATGGACGACC TCTTCCCCCT CATCTTCCCT GCAGAGCCGG CGCAGGCCTC TGGCCCCTAT 
GTGGAGATCA TCGAGCAGCC CAAGCAGCGG GGCATGCGCT TCCGCTACAA GTGTGAGGGC 
CGCTCAGCTG GCAGCATCCC TGGAGAGAGG AGCACGGACA CCACCAAGAC CCACCCCACT 
ATCAAGATCA ATGGCTACAC CGGGCCAGGG ACAGTCCGCA TCTCCCTGGT CACCAAGGAC 
CCCCCTCACC GGCCTCACCC TCACGAGCTA GTGGGGAAAG ACTGCCGGGA TGGCTTCTAT 
GAGGCTGAGC TCTGCCCGGA CCGCTGCATC CACAGCTTTC AGAACCTGGG GATCCAGTGT 
GTAAAGAAGC GGGACCTGGA GCAGGCCATC AGCCAGCGCA TCCAGACCAA CAACAACCCC 
TTCCAAGTTC CCATAGAAGA GCAGCGCGGG GACTACGACC TGAATGCCGT CCGGCTCTGC 
TTCCAGGTGA CAGTGCGGGA CCCGGCAGGC AGGCCCCTCC GCCTGGCGCC TGTCCTCTCT 
CACCCCATCT TTGACAACCG CGCCCCCAAC ACCGCCGAGC TCAAGATCTG CCGGGTGAAT 
CGGAACTCTG GGAGCTGCCT CGGCGGGGAT GAGATCTTCC TGCTGTGTGA CAAGGTGCAG 
AAAGAGGACA TCGAGGTGTA TTTCACGGGA CCAGGCTGGG AGGCCCGAGG CTCTTTTTCA 
CAAGCTGACG TGCACCGGCA AGTGGCCATC GTGTTCCGGA CGCCGCCCTA CGCGGACCCC 
GGCCTGCAGG CCCCTGTGCG CGTCTCCATG CAGCTGCGGC GGCCTTCCGA TCGGGAGCTC 
AGTGAGCCCA TGGAATTCCA GTACTTGCCA GACACAGACG ATCGTCACCG GATTGAGGAG 
AAGCGCAAAA GGACGTACGA GACCTTCAAG AGCATCATGA AAAAGAGCCC TTTCAATGGA 
CCCACCGACC CCCGGCCTCC AACCCGGCGC ATCGCTGTGC CTAACCGCGG CTCAGCCTCC 
ATCCCCAAGC CAGCTCCCCA GCCCTATTCC TTTACGCCAT CTCTCAGCAC CATCAACTTT 
GAGGAGTTTT CCCCCATGGT CTTTCCTTCT GGGCAGATCC CAAGCCAGAC CTCGGCCTTG 
GCACCAGCCC CCACCCCGGT CCTGACCCAG ACCCAAGTCC TGGCCCCAGC CCCGGCCCCA 
GCCCCAGGCA TGGCATCAAC CCTGGCCCAG GCCCTAGCCC CAGGCCTGGC TCAGGCTGTG 
ACCCCGCCTG CCCCCAGGAC CAACCAGACC GGGGAAGGGA CACTGACAGA GGCCCTGCTG 
CAGCTGCAGT TTGATACCGA TGAAGACCTG GGGGCTCTGC TTGGCAACAA CACTGACCCT 
GCCGTGTTCA CAGACCTGGC ATCTGTCGAC AACTCTGAGT TTCAGCAGTT GCTGAACCAG 
GGTGTACCCA TGGGCCCCCA CACAGCTGAG CCCATGCTGA TGGAGTACCC TGAGGCTATA 
ACTCGCCTGG TGACAGGGTC CCAAAGGCCC CCTGACCCAG CTCCCACTCC CCTGGGGCCC 
CCTGGGCTCA CCAATGGCCT CCTCTCGGGG GATGAAGACT TCTCCTCCAT CGCGGATGTG 
GACTTCTCAG CCCTTCTGAG TCAGATCAGC TCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High levels of acetoacetate and glucose increase expression of cytokines in bovine hepatocytes, through activation of the NF-?B signalling pathway.
The Journal of dairy research83(1)51-7(2016 Feb)
Li Y,Ding H,Wang X,Liu L,Huang D,Zhang R,Guo L,Wang Z,Li X,Liu G,Wu J,Li X

Cytopathic BVDV-1 strain induces immune marker production in bovine cells through the NF-?B signaling pathway.
Molecular immunology68(2 Pt A)213-22(2015 Dec)
Fredericksen F,Carrasco G,Villalba M,Olavarr?a VH

SREBP-1c overactivates ROS-mediated hepatic NF-?B inflammatory pathway in dairy cows with fatty liver.
Cellular signalling27(10)2099-109(2015 Oct)
Li X,Huang W,Gu J,Du X,Lei L,Yuan X,Sun G,Wang Z,Li X,Liu G

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

RELA cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報