Gene Symbol | BOLA-DRA |
Entrez Gene ID | 506214 |
Full Name | major histocompatibility complex, class II, DR alpha |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
ORF » Species Summary » Bos taurus » BOLA-DRA cDNA ORF clone
Gene Symbol | BOLA-DRA |
Entrez Gene ID | 506214 |
Full Name | major histocompatibility complex, class II, DR alpha |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001012677.1 | NP_001012695.1 | major histocompatibility complex, class II, DR alpha precursor |
Pan troglodytes (chimpanzee) | PATR-DRA | NP_001127811.1 |
Gallus gallus (chicken) | BLA | NP_001231990.1 |
Bos taurus (cattle) | BOLA-DRA | NP_001012695.1 |
Mus musculus (house mouse) | H2-Ea-ps | XP_003688998.1 |
Rattus norvegicus (Norway rat) | RT1-Da | NP_001008847.1 |
Homo sapiens (human) | HLA-DRA | NP_061984.2 |
MAMU-DRA | NP_001127770.1 | |
Canis lupus familiaris (dog) | DLA-DRA | NP_001011723.1 |
Greater expression of TLR2, TLR4, and IL6 due to negative energy balance is associated with lower expression of HLA-DRA and HLA-A in bovine blood neutrophils after intramammary mastitis challenge with Streptococcus uberis.
Moyes KM, Drackley JK, Morin DE, Loor JJ
Functional & integrative genomics10(1)53-61(2010 Mar)
Short communication: Identification of allelic variation at the bovine DRA locus by polymerase chain reaction-single strand conformational polymorphism.
Zhou H, Hickford JG, Fang Q, Byun SO
Journal of dairy science90(4)1943-6(2007 Apr)
Characterization of 954 bovine full-CDS cDNA sequences.
Harhay GP, Sonstegard TS, Keele JW, Heaton MP, Clawson ML, Snelling WM, Wiedmann RT, Van Tassell CP, Smith TP
BMC genomics6166(2005 Nov)
Structure of the BoLA-DRB3 gene and promoter.
Russell GC, Smith JA, Oliver RA
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics31(3)145-51(2004 Jun)
Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index.
Sonstegard TS, Capuco AV, White J, Van Tassell CP, Connor EE, Cho J, Sultana R, Shade L, Wray JE, Wells KD, Quackenbush J
Mammalian genome : official journal of the International Mammalian Genome Society13(7)373-9(2002 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
ALOX5AP, CPNE3, IL1R2, IL6, TLR2, TLR4, and THY1 were upregulated in blood polymorphonuclear cells in negative energy balance versus positive energy balance cows.
Title: Greater expression of TLR2, TLR4, and IL6 due to negative energy balance is associated with lower expression of HLA-DRA and HLA-A in bovine blood neutrophils after intramammary mastitis challenge with Streptococcus uberis.
Four unique SSCP patterns were detected among 384 cattle from New Zealand and sequence analysis revealed that these SSCP patterns represent 4 DRA alleles; and 3 single nucleotide polymorphisms were detected in exon 2
Title: Short communication: Identification of allelic variation at the bovine DRA locus by polymerase chain reaction-single strand conformational polymorphism.
The following BOLA-DRA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BOLA-DRA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa39905 | |
Clone ID Related Accession (Same CDS sequence) | NM_001012677.1 | |
Accession Version | NM_001012677.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-13 | |
Organism | Bos taurus(cattle) | |
Product | major histocompatibility complex, class II, DR alpha precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BT021059.1. On Aug 25, 2005 this sequence version replaced XM_582632.1. ##Evidence-Data-START## Transcript exon combination :: BT021059.1, BC142119.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN05861751, SAMN05861853 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCATAA CCAGGGTCCC AATATTAGGA CTTTTCATCA CTGTCCTGAT CGGCCTACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001012695.1 |
CDS | 84..845 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001012677.1 |
1 | ATGGCCATAA CCAGGGTCCC AATATTAGGA CTTTTCATCA CTGTCCTGAT CGGCCTACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Greater expression of TLR2, TLR4, and IL6 due to negative energy balance is associated with lower expression of HLA-DRA and HLA-A in bovine blood neutrophils after intramammary mastitis challenge with Streptococcus uberis. |
Short communication: Identification of allelic variation at the bovine DRA locus by polymerase chain reaction-single strand conformational polymorphism. |
Characterization of 954 bovine full-CDS cDNA sequences. |
Structure of the BoLA-DRB3 gene and promoter. |
Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. |