ORM1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	ORM1
Entrez Gene ID	497200
Full Name	orosomucoid 1
Synonyms	AGP
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001040502.2	NP_001035592.1	alpha-1-acid glycoprotein precursor

Pathways from BioSystems

Homologies

	LOC703984	XP_001100289.1
Homo sapiens (human)	ORM1	NP_000598.2
Bos taurus (cattle)	ORM1	NP_001035592.1
Pan troglodytes (chimpanzee)	ORM1	XP_003312295.1
Rattus norvegicus (Norway rat)	Orm1	NP_445740.1
Canis lupus familiaris (dog)	ORM1	XP_003431634.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of ?1-acid glycoprotein and lipopolysaccharide binding protein in visceral and subcutaneous adipose tissue of dairy cattle.
Rahman MM, Lecchi C, Sauerwein H, Mielenz M, H?u?ler S, Restelli L, Giudice C, Ceciliani F
Veterinary journal (London, England : 1997)203(2)223-7(2015 Feb)

Evidence for a novel, local acute-phase response in the bovine oviduct: progesterone and lipopolysaccharide up-regulate alpha 1-acid-glycoprotein expression in epithelial cells in vitro.
Kowsar R, Hambruch N, Marey MA, Liu J, Shimizu T, Pfarrer C, Miyamoto A
Molecular reproduction and development81(9)861-70(2014 Sep)

Bovine ??-acid glycoprotein, a thermostable version of its human counterpart: insights from Fourier transform infrared spectroscopy and in silico modelling.
Baldassarre M, Galeazzi R, Maggiore B, Tanfani F, Scir? A
Biochimie10219-28(2014 Jul)

An acute-phase protein as a regulator of sperm survival in the bovine oviduct: alpha 1-acid-glycoprotein impairs neutrophil phagocytosis of sperm in vitro.
Liu J, Marey MA, Kowsar R, Hambruch N, Shimizu T, Haneda S, Matsui M, Sasaki M, Hayakawa H, Pfarrer C, Miyamoto A
The Journal of reproduction and development60(5)342-8(2014)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The presence of lipopolysaccharide binding protein (LBP) and alpha1-acid glycoprotein (AGP) was demonstrated in all seven adipose tissue depots. Expression of AGP and LBP suggests that they may have roles as local and systemic inflammatory adipokines.
Title: Expression of ?1-acid glycoprotein and lipopolysaccharide binding protein in visceral and subcutaneous adipose tissue of dairy cattle.

Studied the regulation and immune function of AGP in cultured bovine oviduct epithelial cells.
Title: Evidence for a novel, local acute-phase response in the bovine oviduct: progesterone and lipopolysaccharide up-regulate alpha 1-acid-glycoprotein expression in epithelial cells in vitro.

As in human AGP and several other lipocalins, a temperature-induced molten globule state has been observed in the denaturation pathway of bovine AGP.
Title: Bovine ??-acid glycoprotein, a thermostable version of its human counterpart: insights from Fourier transform infrared spectroscopy and in silico modelling.

results provide evidence that locally produced alpha-1 acid glycoprotein may be involved in protecting sperm from phagocytosis by polymorphonuclear neutrophils in the bovine oviduct
Title: An acute-phase protein as a regulator of sperm survival in the bovine oviduct: alpha 1-acid-glycoprotein impairs neutrophil phagocytosis of sperm in vitro.

study provides evidence that the expression of CD18 was downregulated by the plasma glycoforms of alpha-1 acid glycoprotein and inhibited the chemotaxis of monocytes
Title: Bovine alpha-1 acid glycoprotein can reduce the chemotaxis of bovine monocytes and modulate CD18 expression.

The following ORM1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ORM1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa00337	NM_001040502.2 Latest version!	Bos taurus orosomucoid 1 (ORM1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ORM1 ( NM_001040502.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001035592.1 Bos taurus orosomucoid 1 (ORM1), mRNA.

Price & Availability↑

CloneID	OBa00337
Clone ID Related Accession (Same CDS sequence)	NM_001040502.2
Accession Version	NM_001040502.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 609bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Bos taurus(cattle)
Product	alpha-1-acid glycoprotein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC102740.1. On Aug 31, 2012 this sequence version replaced NM_001040502.1. ##Evidence-Data-START## Transcript exon combination :: BC102740.1, DT854411.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145425 [ECO:0000348] ##Evidence-Data-END##

ATGGCACTGC TTTGGGCTCT CGCTGTCCTG AGCCACCTTC CCCTGCTGGA TGCCCAGAGC 
CCCGAGTGTG CCAACCTGAT GACAGTGGCG CCCATTACCA ATGCCACCAT GGACTTGCTC 
TCTGGCAAGT GGTTTTATAT TGGCTCCGCT TTCCGAAACC CCGAGTACAA TAAGTCGGCT 
AGAGCAATCC AGGCGGCTTT CTTTTACCTT GAGCCCAGGC ACGCAGAGGA CAAGCTGATC 
ACCAGAGAGT ACCAGACCAT TGAGGACAAG TGCGTCTACA ACTGCAGCTT CATAAAAATC 
TATCGTCAGA ATGGGACCTT GTCTAAAGTT GAGTCGGACA GAGAACACTT TGTTGACCTG 
CTGCTCAGCA AGCACTTCAG GACCTTCATG CTTGCTGCCT CCTGGAATGG CACAAAGAAC 
GTGGGGGTGT CCTTCTATGC TGACAAGCCG GAGGTGACCC AGGAGCAGAA GAAAGAGTTC 
TTAGATGTCA TCAAGTGCAT AGGCATCCAG GAATCAGAAA TCATATACAC TGACGAGAAG 
AAGGATGCGT GTGGGCCGCT GGAGAAGCAG CATGAGGAGG AAAGGAAGAA GGAGACAGAA 
GCGTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035592.1
CDS	36..644
Translation	MALLWALAVLSHLPLLDAQSPECANLMTVAPITNATMDLLSGKWFYIGSAFRNPEYNKSARAIQAAFFYLEPRHAEDKLITREYQTIEDKCVYNCSFIKIYRQNGTLSKVESDREHFVDLLLSKHFRTFMLAASWNGTKNVGVSFYADKPEVTQEQKKEFLDVIKCIGIQESEIIYTDEKKDACGPLEKQHEEERKKETEAS

Target ORF information:

RefSeq Version	NM_001040502.2
Organism	Bos taurus(cattle)
Definition	Bos taurus orosomucoid 1 (ORM1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040502.2

ORF Insert Sequence:

ATGGCACTGC TTTGGGCTCT CGCTGTCCTG AGCCACCTTC CCCTGCTGGA TGCCCAGAGC 
CCCGAGTGTG CCAACCTGAT GACAGTGGCG CCCATTACCA ATGCCACCAT GGACTTGCTC 
TCTGGCAAGT GGTTTTATAT TGGCTCCGCT TTCCGAAACC CCGAGTACAA TAAGTCGGCT 
AGAGCAATCC AGGCGGCTTT CTTTTACCTT GAGCCCAGGC ACGCAGAGGA CAAGCTGATC 
ACCAGAGAGT ACCAGACCAT TGAGGACAAG TGCGTCTACA ACTGCAGCTT CATAAAAATC 
TATCGTCAGA ATGGGACCTT GTCTAAAGTT GAGTCGGACA GAGAACACTT TGTTGACCTG 
CTGCTCAGCA AGCACTTCAG GACCTTCATG CTTGCTGCCT CCTGGAATGG CACAAAGAAC 
GTGGGGGTGT CCTTCTATGC TGACAAGCCG GAGGTGACCC AGGAGCAGAA GAAAGAGTTC 
TTAGATGTCA TCAAGTGCAT AGGCATCCAG GAATCAGAAA TCATATACAC TGACGAGAAG 
AAGGATGCGT GTGGGCCGCT GGAGAAGCAG CATGAGGAGG AAAGGAAGAA GGAGACAGAA 
GCGTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of ?1-acid glycoprotein and lipopolysaccharide binding protein in visceral and subcutaneous adipose tissue of dairy cattle.
Veterinary journal (London, England : 1997)203(2)223-7(2015 Feb)
Rahman MM,Lecchi C,Sauerwein H,Mielenz M,H?u?ler S,Restelli L,Giudice C,Ceciliani F

Evidence for a novel, local acute-phase response in the bovine oviduct: progesterone and lipopolysaccharide up-regulate alpha 1-acid-glycoprotein expression in epithelial cells in vitro.
Molecular reproduction and development81(9)861-70(2014 Sep)
Kowsar R,Hambruch N,Marey MA,Liu J,Shimizu T,Pfarrer C,Miyamoto A

Bovine ??-acid glycoprotein, a thermostable version of its human counterpart: insights from Fourier transform infrared spectroscopy and in silico modelling.
Biochimie10219-28(2014 Jul)
Baldassarre M,Galeazzi R,Maggiore B,Tanfani F,Scir? A

An acute-phase protein as a regulator of sperm survival in the bovine oviduct: alpha 1-acid-glycoprotein impairs neutrophil phagocytosis of sperm in vitro.
The Journal of reproduction and development60(5)342-8(2014)
Liu J,Marey MA,Kowsar R,Hambruch N,Shimizu T,Haneda S,Matsui M,Sasaki M,Hayakawa H,Pfarrer C,Miyamoto A

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

ORM1 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報