Gene Symbol | SLC6A8 |
Entrez Gene ID | 282367 |
Full Name | solute carrier family 6 member 8 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » SLC6A8 cDNA ORF clone
Gene Symbol | SLC6A8 |
Entrez Gene ID | 282367 |
Full Name | solute carrier family 6 member 8 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_174611.2 | NP_777036.1 | sodium- and chloride-dependent creatine transporter 1 |
Pan troglodytes (chimpanzee) | SLC6A8 | XP_529227.4 |
Danio rerio (zebrafish) | slc6a8 | XP_695932.1 |
SLC6A8 | XP_001086826.2 | |
Xenopus tropicalis (tropical clawed frog) | LOC100489909 | XP_004916750.1 |
Rattus norvegicus (Norway rat) | Slc6a8 | NP_059044.1 |
Bos taurus (cattle) | SLC6A8 | NP_777036.1 |
Mus musculus (house mouse) | Slc6a8 | NP_001136281.1 |
Homo sapiens (human) | SLC6A8 | NP_005620.1 |
Canis lupus familiaris (dog) | SLC6A8 | XP_005642051.1 |
Down-Regulation of the Na+,Cl- Coupled Creatine Transporter CreaT (SLC6A8) by Glycogen Synthase Kinase GSK3?.
Fezai M, Jema? M, Fakhri H, Chen H, Elsir B, Pelzl L, Lang F
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology40(5)1231-1238(2016)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
PIKfyve in the SGK1 mediated regulation of the creatine transporter SLC6A8.
Strutz-Seebohm N, Shojaiefard M, Christie D, Tavare J, Seebohm G, Lang F
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20(6)729-34(2007)
Stimulation of the creatine transporter SLC6A8 by the protein kinase mTOR.
Shojaiefard M, Christie DL, Lang F
Biochemical and biophysical research communications341(4)945-9(2006 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
GSK3ss down-regulates the creatine transporter CreaT, an effect reversed by treatment with the antidepressant Lithium and by co-expression of PKB/Akt.
Title: Down-Regulation of the Na+,Cl- Coupled Creatine Transporter CreaT (SLC6A8) by Glycogen Synthase Kinase GSK3?.
The observations suggest that SGK1 regulates the creatine transporter SLC6A8 at least partially through phosphorylation and activation of PIKfyve.
Title: PIKfyve in the SGK1 mediated regulation of the creatine transporter SLC6A8.
Mammalian target of rapamycin (mTOR) stimulates the creatine transporter SLC6A8 through mechanisms at least partially shared by the serum and glucocorticoid-inducible kinase SGK1.
Title: Stimulation of the creatine transporter SLC6A8 by the protein kinase mTOR.
The following SLC6A8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC6A8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa41404 | |
Clone ID Related Accession (Same CDS sequence) | NM_174611.2 | |
Accession Version | NM_174611.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1908bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Bos taurus(cattle) | |
Product | sodium- and chloride-dependent creatine transporter 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF027197.1. On Jun 3, 2003 this sequence version replaced NM_174611.1. ##Evidence-Data-START## Transcript exon combination :: AF027197.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCAACA AGAGCACGGA GAACGGCATC TACAGCGTGT CCGGCGAGGA GAAGAAGGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_777036.1 |
CDS | 126..2033 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174611.2 |
1 | ATGGCCAACA AGAGCACGGA GAACGGCATC TACAGCGTGT CCGGCGAGGA GAAGAAGGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Down-Regulation of the Na+,Cl- Coupled Creatine Transporter CreaT (SLC6A8) by Glycogen Synthase Kinase GSK3?. |
A whole-genome assembly of the domestic cow, Bos taurus. |
PIKfyve in the SGK1 mediated regulation of the creatine transporter SLC6A8. |
Stimulation of the creatine transporter SLC6A8 by the protein kinase mTOR. |