Gene Symbol | PIK3R2 |
Entrez Gene ID | 282308 |
Full Name | phosphoinositide-3-kinase regulatory subunit 2 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » PIK3R2 cDNA ORF clone
Gene Symbol | PIK3R2 |
Entrez Gene ID | 282308 |
Full Name | phosphoinositide-3-kinase regulatory subunit 2 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_174576.2 | NP_777001.1 | phosphatidylinositol 3-kinase regulatory subunit beta |
Pan troglodytes (chimpanzee) | PIK3R2 | XP_512509.2 |
Gallus gallus (chicken) | PIK3R2 | XP_001233341.3 |
Xenopus tropicalis (tropical clawed frog) | pik3r2 | XP_002934855.2 |
Homo sapiens (human) | PIK3R2 | NP_005018.1 |
PIK3R2 | XP_001114094.1 | |
Danio rerio (zebrafish) | pik3r2 | NP_997987.1 |
Canis lupus familiaris (dog) | PIK3R2 | XP_852406.2 |
Rattus norvegicus (Norway rat) | Pik3r2 | NP_071521.2 |
Bos taurus (cattle) | PIK3R2 | NP_777001.1 |
Mus musculus (house mouse) | Pik3r2 | NP_032867.2 |
Insulin stimulates glucose uptake via a phosphatidylinositide 3-kinase-linked signaling pathway in bovine mammary epithelial cells.
Zhao K, Liu HY, Zhou MM, Zhao FQ, Liu JX
Journal of dairy science97(6)3660-5(2014)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation.
Hale BG, Batty IH, Downes CP, Randall RE
The Journal of biological chemistry283(3)1372-80(2008 Jan)
Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling.
Hale BG, Jackson D, Chen YH, Lamb RA, Randall RE
Proceedings of the National Academy of Sciences of the United States of America103(38)14194-9(2006 Sep)
Localization of the insulin receptor and phosphoinositide 3-kinase in detergent-resistant membrane rafts of rod photoreceptor outer segments.
Rajala RV, Elliott MH, McClellan ME, Anderson RE
Advances in experimental medicine and biology572491-7(2006)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These data suggest a model by which NS1 activates PI3K catalytic activity by masking a normal regulatory element specific to the p85beta inter-SH2 domain.
Title: Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation.
Results report that influenza A virus NS1 binds directly to p85beta, a regulatory subunit of phosphatidylinositol-3-kinase (PI3K), but not to the related p85alpha subunit.
Title: Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling.
insulin receptor and phosphoinositide 3-kinase in detergent-resistant membrane rafts of rod photoreceptor outer segments
Title: Localization of the insulin receptor and phosphoinositide 3-kinase in detergent-resistant membrane rafts of rod photoreceptor outer segments.
The following PIK3R2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PIK3R2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa43019 | |
Clone ID Related Accession (Same CDS sequence) | NM_174576.2 | |
Accession Version | NM_174576.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2175bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Bos taurus(cattle) | |
Product | phosphatidylinositol 3-kinase regulatory subunit beta | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC118113.1. On Jul 14, 2006 this sequence version replaced NM_174576.1. ##Evidence-Data-START## Transcript exon combination :: BC118113.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145412, SAMN03145413 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCTGGCC CTGAGGGCTT CCAATACCGT GCATTGTACC CATTCCGCCG GGAGAGGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_777001.1 |
CDS | 498..2672 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174576.2 |
1 | ATGGCTGGCC CTGAGGGCTT CCAATACCGT GCATTGTACC CATTCCGCCG GGAGAGGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Insulin stimulates glucose uptake via a phosphatidylinositide 3-kinase-linked signaling pathway in bovine mammary epithelial cells. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation. |
Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling. |
Localization of the insulin receptor and phosphoinositide 3-kinase in detergent-resistant membrane rafts of rod photoreceptor outer segments. |