ICAM1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	ICAM1
Entrez Gene ID	281839
Full Name	intercellular adhesion molecule 1
General protein information	Preferred Names intercellular adhesion molecule 1 Names intercellular adhesion molecule 1 ICAM-1 intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174348.2	NP_776773.1	intercellular adhesion molecule 1 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ICAM1	NP_776773.1
Rattus norvegicus (Norway rat)	Icam1	NP_037099.1
Homo sapiens (human)	ICAM1	NP_000192.2
	ICAM1	NP_001040600.1
Canis lupus familiaris (dog)	ICAM1	NP_001003291.1
Pan troglodytes (chimpanzee)	ICAM1	NP_001009946.1
Mus musculus (house mouse)	Icam1	NP_034623.1

Gene Ontology
Bibliography

Related articles in PubMed

Effects of asymmetric dimethylarginine on bovine retinal capillary endothelial cell proliferation, reactive oxygen species production, permeability, intercellular adhesion molecule-1, and occludin expression.
Chen YH, Xu X, Sheng MJ, Zheng Z, Gu Q
Molecular vision17332-40(2011 Feb)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Cloning, sequencing and analysis of cDNA encoding bovine intercellular adhesion molecule-1 (ICAM-1).
Lee E, Kang SG, Kehrli ME Jr
Veterinary immunology and immunopathology59(1-2)121-9(1997 Oct)

Lipoxygenase product formation and cell adhesion during neutrophil-glomerular endothelial cell interaction.
Brady HR, Lamas S, Papayianni A, Takata S, Matsubara M, Marsden PA
The American journal of physiology268(1 Pt 2)F1-12(1995 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ADMA has potent adverse effects on cell proliferation, intracellular ROS generation, cell permeability, levels of ICAM-1, and the tight-junction protein occludin
Title: Effects of asymmetric dimethylarginine on bovine retinal capillary endothelial cell proliferation, reactive oxygen species production, permeability, intercellular adhesion molecule-1, and occludin expression.

The following ICAM1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ICAM1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa41693	NM_174348.2 Latest version!	Bos taurus intercellular adhesion molecule 1 (ICAM1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ICAM1 ( NM_174348.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776773.1 Bos taurus intercellular adhesion molecule 1 (ICAM1), mRNA.

Price & Availability↑

CloneID	OBa41693
Clone ID Related Accession (Same CDS sequence)	NM_174348.2
Accession Version	NM_174348.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1608bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Bos taurus(cattle)
Product	intercellular adhesion molecule 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U65789.1. On or before Mar 29, 2005 this sequence version replaced XM_618128.1, NM_174348.1. ##Evidence-Data-START## Transcript exon combination :: U65789.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END##

ATGGCTCTCG GCGCCGCCCC TGCAGCACAG CTTGCGCTCC TGGCCCTGCT CGGGACTCTG 
CTCCCAGGGC CTGGAGGTGC CGGAATATCA ATACATCCTT CAAAAGCCAT CATACCCCGT 
GGAGACTCCC TGACGGTGAA CTGCAGTAAC TCCTGTGACC AAAAGTCAAC ATTTGGCCTA 
GAGACTGTAT TAATCAAGGA GGAAGTGGGC CGTGGGGACA ACTGGAAGGT TTTTCAACTG 
CGTGATGTGC AGGAAGACAT CGAGCTGTTT TGCTACTCAA ACTGTCACAA GGAACAGACA 
ATAGCTTCAA TGAACCTCAC CGTATACTGG TTCCCGGAGC ATGTGGAGCT GGCTCCCCTG 
CCCCTCTGGC AGCCTGTGGG TGAAGAACTC AACCTGAGCT GCCTGGTGTC TGGCGGGGCC 
CCCCGGGCCC ACCTCTCCGT GGTGCTGCTC CGAGGGGAGG AGGAGCTGGG CCGGCAGCCC 
GTGGGAAAGG GGGAGCCCGC CAAGGTCATG TTCACAGTGC AGTCGAGAAG AGAGGACCAT 
GGCACCAATT TCTCTTGCCG CTGGGAACTG GACCTGCGGT CACAAGGGCT GGAACTCTTC 
CAGAACACCT CGGCCCCCAG GAAGCTCCAG ACCTATGTCC TGCCATCGAT CGACCCTCAC 
CTTGAGGTCC CCCCGATTGT GGAAGTAGGC TCACGGTGGC CGGTGAATTG CACGCTGGAT 
GGACTGTTCC CAGCCTCAGA CGCTAAGGTC TACCTGGTGC TGGGGGACCA GAAACTGGAA 
TCCAATATCA CGTACGATGG TGACTCTGTC TTGGCCAAGG CCTGGATGGA GGAAAATGAG 
GAGGGCACCC ATTCCTTGAA GTGTTCAGTG ACTCTGGGAG AGGTCAGCCG GAGGACGCAA 
GAGAACGTGA CTGTCTATAG CTTCCCACTT CCCACCCTGA CCCTGAGTCC TCCTGAGGTC 
TCAGAATGGA CTACTGTGAC TGTGGAATGT GTGACCCGTG ATGGAGCTGT GGTGAAGCTG 
AATGGAACCT CAGCTGTGCC GCCGGGTCCG AGGGCCCAAT TGAAGCTGAA CGCCAGTGCC 
AGCGACCACA GGAGCAACTT CTCCTGCTCT GCTGCCCTGG AGATAGCTGG GCAGGTGGTC 
CACAAACACC AGACCCTGGA GCTCCATGTC CTGTACGGCC CCCGACTAGA CCAGCGGGAT 
TGCCCGGGAA ACTGGACGTG GCAGGAAGGC TCGGAACAGA CCCTGAAGTG CGAGGCTCAG 
GGGAACCCAA TCCCCAAGCT GAACTGTAGC CGGAAAGGGG ACGGGGCTTC GCTGCCCATC 
GGGGACCTGA GGCCCGTTAG GCGGGAGGTG GCGGGCACCT ACCTGTGTCG GGCCACCAGC 
GCTCGTGGCA GAGTCACCCG TGAAGTGGTC CTGAACGTGC TCCACGGCCA GAATATCCTG 
GACATTGTCA TTCCGGTAGT AGCTGTGACC CTCATCTTGG GTGCTCTGGG CACCGCCGGT 
TATGTCTATA ACTACCAGCG GAAGATCCAG AAATACGAGC TGCAGAAGGC CCGGAAGGCC 
CAAGAAGAGG CTGCCTTGAA ACTGAATGCA CAATCCACGC CGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776773.1
CDS	554..2161
Translation	MALGAAPAAQLALLALLGTLLPGPGGAGISIHPSKAIIPRGDSLTVNCSNSCDQKSTFGLETVLIKEEVGRGDNWKVFQLRDVQEDIELFCYSNCHKEQTIASMNLTVYWFPEHVELAPLPLWQPVGEELNLSCLVSGGAPRAHLSVVLLRGEEELGRQPVGKGEPAKVMFTVQSRREDHGTNFSCRWELDLRSQGLELFQNTSAPRKLQTYVLPSIDPHLEVPPIVEVGSRWPVNCTLDGLFPASDAKVYLVLGDQKLESNITYDGDSVLAKAWMEENEEGTHSLKCSVTLGEVSRRTQENVTVYSFPLPTLTLSPPEVSEWTTVTVECVTRDGAVVKLNGTSAVPPGPRAQLKLNASASDHRSNFSCSAALEIAGQVVHKHQTLELHVLYGPRLDQRDCPGNWTWQEGSEQTLKCEAQGNPIPKLNCSRKGDGASLPIGDLRPVRREVAGTYLCRATSARGRVTREVVLNVLHGQNILDIVIPVVAVTLILGALGTAGYVYNYQRKIQKYELQKARKAQEEAALKLNAQSTPP

Target ORF information:

RefSeq Version	NM_174348.2
Organism	Bos taurus(cattle)
Definition	Bos taurus intercellular adhesion molecule 1 (ICAM1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174348.2

ORF Insert Sequence:

ATGGCTCTCG GCGCCGCCCC TGCAGCACAG CTTGCGCTCC TGGCCCTGCT CGGGACTCTG 
CTCCCAGGGC CTGGAGGTGC CGGAATATCA ATACATCCTT CAAAAGCCAT CATACCCCGT 
GGAGACTCCC TGACGGTGAA CTGCAGTAAC TCCTGTGACC AAAAGTCAAC ATTTGGCCTA 
GAGACTGTAT TAATCAAGGA GGAAGTGGGC CGTGGGGACA ACTGGAAGGT TTTTCAACTG 
CGTGATGTGC AGGAAGACAT CGAGCTGTTT TGCTACTCAA ACTGTCACAA GGAACAGACA 
ATAGCTTCAA TGAACCTCAC CGTATACTGG TTCCCGGAGC ATGTGGAGCT GGCTCCCCTG 
CCCCTCTGGC AGCCTGTGGG TGAAGAACTC AACCTGAGCT GCCTGGTGTC TGGCGGGGCC 
CCCCGGGCCC ACCTCTCCGT GGTGCTGCTC CGAGGGGAGG AGGAGCTGGG CCGGCAGCCC 
GTGGGAAAGG GGGAGCCCGC CAAGGTCATG TTCACAGTGC AGTCGAGAAG AGAGGACCAT 
GGCACCAATT TCTCTTGCCG CTGGGAACTG GACCTGCGGT CACAAGGGCT GGAACTCTTC 
CAGAACACCT CGGCCCCCAG GAAGCTCCAG ACCTATGTCC TGCCATCGAT CGACCCTCAC 
CTTGAGGTCC CCCCGATTGT GGAAGTAGGC TCACGGTGGC CGGTGAATTG CACGCTGGAT 
GGACTGTTCC CAGCCTCAGA CGCTAAGGTC TACCTGGTGC TGGGGGACCA GAAACTGGAA 
TCCAATATCA CGTACGATGG TGACTCTGTC TTGGCCAAGG CCTGGATGGA GGAAAATGAG 
GAGGGCACCC ATTCCTTGAA GTGTTCAGTG ACTCTGGGAG AGGTCAGCCG GAGGACGCAA 
GAGAACGTGA CTGTCTATAG CTTCCCACTT CCCACCCTGA CCCTGAGTCC TCCTGAGGTC 
TCAGAATGGA CTACTGTGAC TGTGGAATGT GTGACCCGTG ATGGAGCTGT GGTGAAGCTG 
AATGGAACCT CAGCTGTGCC GCCGGGTCCG AGGGCCCAAT TGAAGCTGAA CGCCAGTGCC 
AGCGACCACA GGAGCAACTT CTCCTGCTCT GCTGCCCTGG AGATAGCTGG GCAGGTGGTC 
CACAAACACC AGACCCTGGA GCTCCATGTC CTGTACGGCC CCCGACTAGA CCAGCGGGAT 
TGCCCGGGAA ACTGGACGTG GCAGGAAGGC TCGGAACAGA CCCTGAAGTG CGAGGCTCAG 
GGGAACCCAA TCCCCAAGCT GAACTGTAGC CGGAAAGGGG ACGGGGCTTC GCTGCCCATC 
GGGGACCTGA GGCCCGTTAG GCGGGAGGTG GCGGGCACCT ACCTGTGTCG GGCCACCAGC 
GCTCGTGGCA GAGTCACCCG TGAAGTGGTC CTGAACGTGC TCCACGGCCA GAATATCCTG 
GACATTGTCA TTCCGGTAGT AGCTGTGACC CTCATCTTGG GTGCTCTGGG CACCGCCGGT 
TATGTCTATA ACTACCAGCG GAAGATCCAG AAATACGAGC TGCAGAAGGC CCGGAAGGCC 
CAAGAAGAGG CTGCCTTGAA ACTGAATGCA CAATCCACGC CGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effects of asymmetric dimethylarginine on bovine retinal capillary endothelial cell proliferation, reactive oxygen species production, permeability, intercellular adhesion molecule-1, and occludin expression.
Molecular vision17332-40(2011 Feb)
Chen YH,Xu X,Sheng MJ,Zheng Z,Gu Q

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Cloning, sequencing and analysis of cDNA encoding bovine intercellular adhesion molecule-1 (ICAM-1).
Veterinary immunology and immunopathology59(1-2)121-9(1997 Oct)
Lee E,Kang SG,Kehrli ME Jr

Lipoxygenase product formation and cell adhesion during neutrophil-glomerular endothelial cell interaction.
The American journal of physiology268(1 Pt 2)F1-12(1995 Jan)
Brady HR,Lamas S,Papayianni A,Takata S,Matsubara M,Marsden PA